Results 1 to 10 of about 116,875 (269)

Multifocal nodular lesions in fatty liver mimicking neoplastic disease: a case report

Future Science OA, 2023
Usually, fatty hepatic infiltration is diffuse and homogeneous. However, in some cases, it can be localized simulating benign or malignant tumors. We present a case of a 61-year-old female patient with family history of malignancy: sister with lung ...
Manel Moalla, Amal Khsiba, Moufida Mahmoudi, Khaled Bouzaidi, Emna Chelbi, Asma Ben Mohamed, Manel Yakoubi, Mouna Medhioub, Lamine Hamzaoui, Mohamed Moussadek Azzouz   +9 more
doaj   +1 more source

Liver Ultrasound Elastography in Non-Alcoholic Fatty Liver Disease: A State-of-the-Art Summary

Diagnostics, 2023
Non-alcoholic fatty liver disease (NAFLD) is a chronic disease which is currently the most common hepatic disorder affecting up to 38% of the general population with differences according to age, country, ethnicity and sex. Both genetic and acquired risk
Rosanna Villani, Pierluigi Lupo, Moris Sangineto, Antonino Davide Romano, Gaetano Serviddio   +4 more
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Steatosis and Metabolic Disorders Associated with Synergistic Activation of the CAR/RXR Heterodimer by Pesticides

Cells, 2023
The nuclear receptor, constitutive androstane receptor (CAR), which forms a heterodimer with the retinoid X receptor (RXR), was initially reported as a transcription factor that regulates hepatic genes involved in detoxication and energy metabolism ...
Yannick Dauwe, Lucile Mary, Fabiana Oliviero, Marina Grimaldi, Patrick Balaguer, Véronique Gayrard, Laïla Mselli-Lakhal   +6 more
doaj   +1 more source

Association of physical activity and fine motor performance in individuals with type 2 diabetes mellitus and/or non-alcoholic fatty liver disease

Annals of Medicine, 2023
Background Fine motor performance may serve as an early warning sign for reduced cognitive function. Physical activity can help preserve cognitive function; however, the relationship between fine motor performance and physical activity is not well ...
Ali A. Weinstein, Dung Ngo, Leyla de Avila, Jillian K. Price, Pegah Golabi, Patrick Austin, Carey Escheik, Lynn H. Gerber, Zobair M. Younossi   +8 more
doaj   +1 more source

Western Diet Causes Obesity-Induced Nonalcoholic Fatty Liver Disease Development by Differentially Compromising the Autophagic Response

Antioxidants, 2020
Nonalcoholic fatty liver disease (NAFLD) is characterized by the development of steatosis, which can ultimately compromise liver function. Mitochondria are key players in obesity-induced metabolic disorders; however, the distinct role of hypercaloric ...
Ines C. M. Simoes, Agnieszka Karkucinska-Wieckowska, Justyna Janikiewicz, Sylwia Szymanska, Maciej Pronicki, Pawel Dobrzyn, Michal Dabrowski, Agnieszka Dobrzyn, Paulo J. Oliveira, Hans Zischka, Yaiza Potes, Mariusz R. Wieckowski   +11 more
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New Perspectives of S-Adenosylmethionine (SAMe) Applications to Attenuate Fatty Acid-Induced Steatosis and Oxidative Stress in Hepatic and Endothelial Cells

Molecules, 2020
S-adenosylmethionine (SAMe) is an endogenous methyl donor derived from ATP and methionine that has pleiotropic functions. Most SAMe is synthetized and consumed in the liver, where it acts as the main methylating agent and in protection against the free ...
Laura Vergani, Francesca Baldini, Mohamad Khalil, Adriana Voci, Pietro Putignano, Niccolò Miraglia   +5 more
doaj   +1 more source

Oxidative Stress and Pro-Inflammatory Status in Patients with Non-Alcoholic Fatty Liver Disease

Antioxidants, 2020
Background: Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive fat accumulation, especially triglycerides, in hepatocytes. If the pathology is not properly treated, it can progress to nonalcoholic steatohepatitis (NASH) and continue ...
Margalida Monserrat-Mesquida, Magdalena Quetglas-Llabrés, Manuela Abbate, Sofía Montemayor, Catalina M. Mascaró, Miguel Casares, Silvia Tejada, Itziar Abete, Maria Angeles Zulet, Josep A. Tur, J. Alfredo Martínez, Antoni Sureda   +11 more
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Detectability of Liver Steatosis and Fibrosis with Transient Elastography and Controlled Attenuation Parameter in Residents of St. Petersburg

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2021
Aim. Estimation of the liver steatosis and fibrosis incidence with transient elastography and the controlled attenuation parameter in residents of St. Petersburg.Materials and methods.
V. P. Kovyazina, K. L. Raikhelson, M. K. Prashnova, E. V. Pazenko, L. K. Palgova, E. A. Kondrashina   +5 more
doaj   +1 more source

Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome

Frontiers in Endocrinology, 2023
IntroductionPrader-Willi syndrome (PWS) is a rare genetic disorder characterized by loss of expression of paternal chromosome 15q11.2-q13 genes. Individuals with PWS exhibit unique physical, endocrine, and metabolic traits associated with severe obesity.
Devis Pascut, Pablo J. Giraudi, Cristina Banfi, Stefania Ghilardi, Claudio Tiribelli, Claudio Tiribelli, Adele Bondesan, Diana Caroli, Alessandro Minocci, Graziano Grugni, Graziano Grugni, Alessandro Sartorio   +11 more
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The Hepatic Antisteatosis Effect of Xanthohumol in High-Fat Diet-Fed Rats Entails Activation of AMPK as a Possible Protective Mechanism

Foods, 2023
Obesity is the leading cause of non-alcoholic fatty liver disease by provoking hyperglycemia, hyperlipidemia, insulin resistance, oxidative stress, and inflammation.
Hebatallah Husseini Atteia, Nora A. AlFaris, Ghedeir M. Alshammari, Eman Alamri, Salwa Fares Ahmed, Renad Albalwi, Sahar Abdel-Latif Abdel-Sattar   +6 more
doaj   +1 more source