Results 1 to 10 of about 141,920 (316)

Stable Isotopic Tracer Phospholipidomics Reveals Contributions of Key Phospholipid Biosynthetic Pathways to Low Hepatocyte Phosphatidylcholine to Phosphatidylethanolamine Ratio Induced by Free Fatty Acids

open access: yesMetabolites, 2021
There is a strong association between hepatocyte phospholipid homeostasis and non-alcoholic fatty liver disease (NAFLD). The phosphatidylcholine to phosphatidylethanolamine ratio (PC/PE) often draws special attention as genetic and dietary disruptions to
Kang-Yu Peng   +7 more
doaj   +1 more source

Association between weight-adjusted-waist index with hepatic steatosis and liver fibrosis: a nationally representative cross-sectional study from NHANES 2017 to 2020

open access: yesFrontiers in Endocrinology, 2023
BackgroundThe negative effects of obesity on hepatic steatosis and fibrosis have received considerable attention in recent years. The weight-adjusted-waist index (WWI) reflects weight-independent centripetal obesity.
Yun Shen   +10 more
doaj   +1 more source

Cancer and hepatic steatosis [PDF]

open access: yesESMO Open, 2021
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent and increasing liver disease, which encompasses a variety of liver diseases of different severity. NAFLD can lead to liver cirrhosis with all its complications as well as hepatocellular carcinoma (HCC). Steatosis of the liver is not only related to obesity and other metabolic risk factors,
Paternostro, R.   +3 more
openaire   +2 more sources

Differential Lipid Accumulation on HepG2 Cells Triggered by Palmitic and Linoleic Fatty Acids Exposure

open access: yesMolecules, 2023
Lipid metabolism pathways such as β-oxidation, lipolysis and, lipogenesis, are mainly associated with normal liver function. However, steatosis is a growing pathology caused by the accumulation of lipids in hepatic cells due to increased lipogenesis ...
Francisca S. Teixeira   +5 more
doaj   +1 more source

IGFBP-2 as a biomarker in NAFLD improves hepatic steatosis: an integrated bioinformatics and experimental study

open access: yesEndocrine Connections, 2021
Background and aims: Non-alcoholic fatty liver disease (NAFLD) has become a common chronic liver disease in the world. Simple steatosis (SS) is the early phase of NAFLD.
Xu Chen   +4 more
doaj   +1 more source

Steatosis and hepatitis C [PDF]

open access: yesGastroenterology Report, 2015
Hepatitis C virus (HCV) infection is a common liver disease worldwide with a high rate of chronicity (75-80%) in infected individuals. The chronic form of HCV leads to steatosis, cirrhosis and hepatocellualr carcinoma. Steatosis is prevalent in HCV patients (55%) due to a combination of viral factors (effect of viral proteins on some of the ...
Modaresi Esfeh, Jamak   +1 more
openaire   +2 more sources

The Role of the Gut-Liver Axis in Metabolic Dysfunction-Associated Fatty Liver Disease

open access: yesFrontiers in Immunology, 2021
The complex interplay between the gut microbiota, the intestinal barrier, the immune system and the liver is strongly influenced by environmental and genetic factors that can disrupt the homeostasis leading to disease.
Rosa Martín-Mateos, Agustín Albillos
doaj   +1 more source

PHARMACOEPIDEMIOLOGICAL EVALUATION OF HEPATOTROPIC THERAPY IN REAL CLINICAL PRACTICE

open access: yesФармакоэкономика, 2015
Chronic liver diseases are a serious problem and a common cause of suffering and death in all countries. Non-alcoholic fatty liver disease (NAFLD) is a major cause of chronic liver diseases.
D. V. Blinov   +2 more
doaj   +1 more source

EVALUATION OF LETHALITY CAUSED BY ACUTE POISONING WITH PSYCHOACTIVE DRUGS IN ELDERLY AND SENILE PATIENTS IN N.V. SKLIFOSOVSKY RESEARCH INSTITUTE FOR EMERGENCY MEDICINE DURING 2013–2015

open access: yesНеотложная медицинская помощь, 2018
We performed the clinical and morphological analysis of 84 elderly and senile patients, died of poisonings with psychoactive drugs in 2013–2015. There were two main drug agents: benzodiazepines and barbiturates. During the first 5 days intoxication was a
L. N. Zimina   +6 more
doaj   +1 more source

Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application

open access: yesFrontiers in Pharmacology, 2020
Non-alcoholic fatty liver disease (NAFLD) is a common chronic liver disease with high prevalence in the developed countries. NAFLD has been considered as one of the leading causes of cryptogenic cirrhosis and chronic liver disease.
Yu Xu   +7 more
doaj   +1 more source

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