Results 21 to 30 of about 116,875 (269)

Key Signaling in Alcohol-Associated Liver Disease: The Role of Bile Acids

Cells, 2022
Alcohol-associated liver disease (ALD) is a spectrum of diseases, the onset and progression of which are due to chronic alcohol use. ALD ranges, by increasing severity, from hepatic steatosis to alcoholic hepatitis (AH) and alcohol-associated cirrhosis ...
Grayson W. Way, Kaitlyn G. Jackson, Shreya R. Muscu, Huiping Zhou   +3 more
doaj   +1 more source

Multifocal nodular steatosis

Journal of the Belgian Society of Radiology, 2013
Background: A 62-year-old male with no medical history underwent an ultrasonography of the abdomen because of changed bowel habits and abdominal pain. CT-scan of the abdomen was performed, which initially suggested liver metastases. However, no primary tumor could be identified.
Fassaert, TA, Ranschaert, ER, Jong, MDF de, Dubelaar, I   +3 more
openaire   +5 more sources

Drivers of cardiovascular disease in metabolic dysfunction-associated steatotic liver disease: the threats of oxidative stress

Frontiers in Cardiovascular Medicine
Non-alcoholic fatty liver disease (NAFLD), now known as metabolic-associated steatotic liver disease (MASLD), is the most common liver disease worldwide, with a prevalence of 38%. In these patients, cardiovascular disease (CVD) is the number one cause of
Erika T. Minetti, Naomi M. Hamburg, Reiko Matsui   +2 more
doaj   +1 more source

Genetic Polymorphisms and Diversity in Nonalcoholic Fatty Liver Disease (NAFLD): A Mini Review

Biomedicines, 2022
Nonalcoholic fatty liver disease (NAFLD) is a common liver disease with a wide spectrum of liver conditions ranging from hepatic steatosis to nonalcoholic steatohepatitis (NASH), fibrosis, cirrhosis, and hepatocellular carcinoma.
Siti Aishah Sulaiman, Vicneswarry Dorairaj, Muhammad Nafiz Haidi Adrus   +2 more
doaj   +1 more source

Efficacy of pioglitazone in treatment of metabolic dysfunction-associated fatty liver disease

Al-Azhar Assiut Medical Journal
Background and aim Nonalcoholic fatty liver disease has emerged as a major public health challenge, with limited approved pharmacological therapies.
Mahmoud M. Khafagi, Hamdy M. Moustafa, Ahmed A. Ahmed, Mohamed A. Bashir, Abdelghany Aish, Amro M. Hassan   +5 more
doaj   +1 more source

Alcoholic hepatitis and metabolic disturbance in female mice: a more tractable model than Nrf2−/− animals

Disease Models & Mechanisms, 2020
Alcoholic hepatitis (AH) is the dramatic acute presentation of alcoholic liver disease, with a 15% mortality rate within 28 days in severe cases. Research into AH has been hampered by the lack of effective and reproducible murine models that can be ...
Lozan Sheriff, Reenam S. Khan, Raquel Saborano, Richard Wilkin, Nguyet-Thin Luu, Ulrich L. Gunther, Stefan G. Hubscher, Philip N. Newsome, Patricia F. Lalor   +8 more
doaj   +1 more source

Vibration-Controlled Transient Elastography and Controlled Attenuation Parameter for the Diagnosis of Liver Steatosis and Fibrosis in Patients with Nonalcoholic Fatty Liver Disease

Diagnostics, 2021
Vibration-Controlled Transient Elastography (VCTE) with Controlled Attenuation Parameter (CAP) is a widely used non-invasive technique for concomitant assessment of liver steatosis and fibrosis in patients with nonalcoholic fatty liver disease (NAFLD ...
Sebastian Zenovia, Carol Stanciu, Catalin Sfarti, Ana-Maria Singeap, Camelia Cojocariu, Irina Girleanu, Mihaela Dimache, Stefan Chiriac, Cristina Maria Muzica, Robert Nastasa, Laura Huiban, Tudor Cuciureanu, Anca Trifan   +12 more
doaj   +1 more source

Metabolite Profile Characterization of Cyanobacterial Strains with Bioactivity on Lipid Metabolism Using In Vivo and In Vitro Approaches

Marine Drugs, 2023
Cyanobacteria have demonstrated their therapeutic potential for many human diseases. In this work, cyanobacterial extracts were screened for lipid reducing activity in zebrafish larvae and in fatty-acid-overloaded human hepatocytes, as well as for ...
Tiago Ribeiro, Kristín Jónsdóttir, Rene Hernandez-Bautista, Natália Gonçalves Silva, Begoña Sánchez-Astráin, Afshin Samadi, Finnur F. Eiriksson, Margrét Thorsteinsdóttir, Siegfried Ussar, Ralph Urbatzka   +9 more
doaj   +1 more source

Correlation study of fatty pancreas and fatty liver CT manifestations with biochemical parameters in middle-aged and young adult cholecystectomy patients

BMC Gastroenterology
Background To investigate the correlation between the occurrence of pancreatic steatosis, hepatic steatosis, and cholecystectomy, as well as the associated biochemical parameters.
Yi Zhou, Chao He, Haipeng Zhang
doaj   +1 more source

Gut Microbiota and Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): Emerging Pathogenic Mechanisms and Therapeutic Implications

Livers
Non-alcoholic fatty liver disease (NAFLD), recently redefined as metabolic dysfunction-associated steatotic liver disease (MASLD), is the most common cause of chronic liver disease worldwide.
Farah Abdelhameed, Attia Mustafa, Chris Kite, Lukasz Lagojda, Alexander Dallaway, Nwe Ni Than, Eva Kassi, Ioannis Kyrou, Harpal S. Randeva   +8 more
doaj   +1 more source