Results 1 to 10 of about 257,609 (309)
تخمین جریان زیرسطحی دامنههای حوضه آبخیز با استفاده از مدلهای ناش و SCS [PDF]
مقدمه: تخمین جریان زیرسطحی(SUF) در بسیاری از حوضههای آبریز با پوشش گیاهی مناسب و نفوذ پذیری خاک بالا حائز اهمیت است و نقش اساسی در تولید رواناب مستقیم حوضه دارد.
حسین فریبرزی +2 more
doaj +1 more source
Obesity and binge alcohol intake are deadly combination to induce steatohepatitis: A model of high-fat diet and binge ethanol intake [PDF]
Obesity and binge drinking often coexist and work synergistically to promote steatohepatitis; however, the underlying mechanisms remain obscure. In this mini-review, we briefly summarize clinical evidence of the synergistical effect of obesity and heavy ...
Seonghwan Hwang, Tianyi Ren, Bin Gao
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Pleiotropic effects of ipragliflozin
Type 2 diabetes mellitus and its complications is a serious threat to the health and lives of the world's population. Among the causes of death in type 2 diabetes mellitus are both cardiovascular and non-vascular causes. Sodium-glucose cotransporter type
Nina A. Petunina +5 more
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Axon regeneration of dorsal root ganglia (DRG) neurons after peripheral axotomy involves reconfiguration of gene regulatory circuits to establish regenerative gene programs. However, the underlying mechanisms remain unclear.
Dalia Halawani +7 more
doaj +1 more source
Scramblases as Regulators of Autophagy and Lipid Homeostasis: Implications for NAFLD
Equilibration of phospholipids between the two monolayers of the lipid bilayer of cellular membranes is mediated by scramblases acting as phospholipid shuttling proteins that are critical for cellular function, particularly during inter-organelle contact.
Allen Chen, Wen-Xing Ding, Hong-Min Ni
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Effect of ipragliflozin on metabolic syndrome components and non-alcoholic fatty liver disease
Sodium-glucose cotransporter-2 inhibitors are the new drugs for the treatment of type 2 diabetes mellitus. Its mechanism of action is to increase the excretion of glucose in the urine due to inhibition of reabsorption in the proximal renal tubules, which
N. A. Petunina +2 more
doaj +1 more source
Minian, an open-source miniscope analysis pipeline
Miniature microscopes have gained considerable traction for in vivo calcium imaging in freely behaving animals. However, extracting calcium signals from raw videos is a computationally complex problem and remains a bottleneck for many researchers ...
Zhe Dong +9 more
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Patients with type 2 diabetes mellitus (T2DM) are at increased risk of non-alcoholic fatty liver disease (NAFLD) and might eventually progress to advanced fibrosis, cirrhosis and hepatocellular carcinoma (HCC).
Tran Thi Khanh Tuong +5 more
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New instrumental learning occurs through an unexpected delivery of a rewarding stimulus or the withdrawal of a punishing stimulus. The authors show that D1 receptor-expressing medium spiny neurons (MSNs) in the anterior dorsolateral striatum encode newly
Alexander C. W. Smith +7 more
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Double‐crested cormorants (Phalacrocorax auritus) have been identified as the source of significant mortality to juvenile salmonids (Oncorhynchus spp.) in the Columbia River Basin.
Yasuko Suzuki +4 more
doaj +1 more source

