Results 21 to 30 of about 113,966 (168)

Neutrophil activation at high-fat high-cholesterol and high-fructose diets induces low-grade inflammation in mice [PDF]

open access: yesThe Ukrainian Biochemical Journal
Nonalcoholic fatty liver disease (NAFLD), which can progress to nonalcoholic steatohepatitis (NASH), is a significant health concern affecting a substantial portion of the population.
G. Bila   +4 more
doaj   +1 more source

The Connection between MicroRNAs from Visceral Adipose Tissue and Non-Alcoholic Fatty Liver Disease

open access: yesActa Medica, 2021
Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most important causes of liver disease worldwide leading the foreground cause of liver transplantation.
Veronika Zubáňová   +3 more
doaj   +1 more source

A Sweet Connection? Fructose’s Role in Hepatocellular Carcinoma

open access: yesBiomolecules, 2020
Hepatocellular carcinoma is one of few cancer types that continues to grow in incidence and mortality worldwide. With the alarming increase in diabetes and obesity rates, the higher rates of hepatocellular carcinoma are a result of underlying non ...
Brittany Dewdney   +4 more
doaj   +1 more source

Akkermansia muciniphila and environmental enrichment reverse cognitive impairment associated with high-fat high-cholesterol consumption in rats

open access: yesGut Microbes, 2021
Nonalcoholic steatohepatitis (NASH) is one of the most prevalent diseases globally. A high-fat, high-cholesterol (HFHC) diet leads to an early NASH model.
Sara G. Higarza   +4 more
doaj   +1 more source

Experimental and Investigational Targeted Therapies for the Management of Fibrosis in NASH: An Update

open access: yesJournal of Experimental Pharmacology, 2021
Tsipora M Huisman, Douglas T Dieterich, Scott L Friedman Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, NY, USACorrespondence: Scott L FriedmanIcahn School of Medicine at Mount Sinai, Box 1123, 1425 Madison Ave, Room 1170C,
Huisman TM, Dieterich DT, Friedman SL
doaj  

Disruption of lysosomal proteolysis in astrocytes facilitates midbrain organoid proteostasis failure in an early-onset Parkinson’s disease model

open access: yesNature Communications
Accumulation of advanced glycation end products (AGEs) on biopolymers accompanies cellular aging and drives poorly understood disease processes. Here, we studied how AGEs contribute to development of early onset Parkinson’s Disease (PD) caused by loss-of-
Gustavo Morrone Parfitt   +12 more
doaj   +1 more source

Dendritic Cells and T Cell Subsets in the Development of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis

open access: yesActa Medica Bulgarica, 2021
Nonalcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are associated with steatosis, inflammation and fibrosis. Liver dendritic cells (DCs) are usually tolerogenic in the sinusoidal milleu composed of immunosuppressive ...
Gulubova M.   +4 more
doaj   +1 more source

Lipotoxicity in NASH

open access: yesJournal of Hepatology, 2012
Exposure to a sedentary lifestyle, fat-rich and fiber-poor diets, positive caloric imbalance and an extended life disrupt the metabolic homeostasis causing non-alcoholic fatty liver disease. A subset of patients with this emerging public health problem may develop non-alcoholic steatohepatitis (NASH) and progress to cirrhosis and liver cancer [1 ...
Fuchs, Michael, Sanyal, Arun J.
openaire   +2 more sources

Universality of Nash components [PDF]

open access: yesGames and Economic Behavior, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Dieter Balkenborg, Dries Vermeulen
openaire   +5 more sources

Neuroeconomically dissociable forms of mental accounting are altered in a mouse model of diabetes

open access: yesCommunications Biology
Those with diabetes mellitus are at high-risk of developing psychiatric disorders, especially mood disorders, yet the link between hyperglycemia and altered motivation has not been thoroughly explored.
Chinonso A. Nwakama   +11 more
doaj   +1 more source

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