Results 231 to 240 of about 387,299 (303)

Erythritol and metabolic dysfunction‐associated steatotic liver disease: A sweet friend, bitter foe, or reliable fellow traveler?

Journal of Diabetes Investigation, EarlyView.
Kelly Hiu‐Ching Wong, David Tak‐Wai Lui, Chi‐Ho Lee   +2 more
wiley   +1 more source

Canonical and non‐canonical functions of proteins regulating mitochondrial dynamics in mammalian physiology

The Journal of Physiology, EarlyView.
Abstract figure legend Mitochondria are highly dynamic organelles that continuously remodel their architecture through coordinated cycles of fusion and fission. This review examines the four key GTPases that orchestrate mitochondrial dynamics in mammals: MFN1, MFN2, OPA1, and DRP1.
Rémi Chaney, Vincent Marcangeli, Krystel Desjardins, Shima Taherkhani, Gilles Gouspillou   +4 more
wiley   +1 more source

Pathogenesis and Treatment of Non-alcoholic Steatohepatitis and Its Fibrosis: A Systematic Review. [PDF]

Cureus
Ahmed T, Farooq S, Naveed MA, Shahzad A, Rehman W, Haider T, Noor NN.   +6 more
europepmc   +1 more source

Adaptations of glucagon‐like peptide‐1 receptor agonist‐induced weight loss, drivers of weight regain and future directions of therapeutics

The Journal of Physiology, EarlyView.
Abstract figure legend During GLP‐1RA treatment reduced appetite and energy intake, delayed gastric emptying, decreased visceral fat mass and improved glycaemic control contribute to weight loss. After treatment cessation these benefits are partially or completely reversed, resulting in weight regain, accompanied by increased appetite and energy intake,
Camille E. M. Piguet, Rosie Nucci, Jacqueline L. Beaudry   +2 more
wiley   +1 more source

Efficiency and Safety of Endoscopic Injection Sclerotherapy With Ligation for Esophageal Varices: A Retrospective Study.

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Endoscopic injection sclerotherapy with ligation (EISL) is a combined endoscopic treatment that involves endoscopic injection sclerotherapy (EIS) and endoscopic variceal ligation. This study aimed to compare the efficacy of conventional EIS and EISL in treating esophageal varices and the usefulness of EISL.
Keita Maki, Hiroaki Haga, Kyoko Hoshikawa, Tomohiro Katsumi, Fumiya Suzuki, Fumi Uchiyama, Yoshiyuki Ueno   +6 more
wiley   +1 more source

Integrating spatial and chemical information enhances differentiation of non-alcoholic steatohepatitis states in Raman imaging. [PDF]

Sci Rep
Kondo R, Mizuno Y, Mochizuki K, Hashimoto K, Clément JE, Kumamoto Y, Fujita K, Harada Y, Komatsuzaki T.   +8 more
europepmc   +1 more source

Delayed Argon Plasma Coagulation After Endoscopic Injection Sclerotherapy for Esophageal Varices Reduces Recurrence Risk

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Objectives Argon plasma coagulation (APC) is commonly used as consolidation therapy after endoscopic injection sclerotherapy (EIS) for esophageal varices (EVs); however, the optimal timing of APC remains unclear. This study evaluated the association between the EIS–APC interval and clinical outcomes.
Takumi Yanagita, Takuto Hikichi, Jun Nakamura, Tsunetaka Kato, Minami Hashimoto, Mitsuru Otsuka, Eisuke Kameoka, Rei Suzuki, Mitsuru Sugimoto, Hiroyuki Asama, Hiroshi Shimizu, Kento Osawa, Rei Ohira, Keisuke Kudo, Daiki Nemoto, Masao Kobayakawa, Hiromasa Ohira   +16 more
wiley   +1 more source

Retraction: Ammonia scavenger restores liver and muscle injury in a mouse model of non-alcoholic steatohepatitis with sarcopenic obesity. [PDF]

Front Nutr
Frontiers Editorial Office.
europepmc   +1 more source

Age‐Specific Associations of Polygenic Risk Scores With Advanced Fibrosis and Histological Activity in Biopsy‐Proven MASLD

Liver International, Volume 46, Issue 11, November 2026.
ABSTRACT Background and Aims The genetic susceptibility to MASLD histological severity remains incompletely defined. We assessed the associations between recently developed genome‐wide association studies–derived polygenic risk scores (PRSs) and advanced fibrosis in MASLD.
Samer Gawrieh, Jingyi Tan, Xiuqing Guo, Linus Schwantes‐An, Marco Abreu, Callie J. Zaborenko, Eduardo Vilar‐Gomez, Jeffrey B. Schwimmer, Jerome I. Rotter, Naga Chalasani   +9 more
wiley   +1 more source

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

American Journal of Hematology, Volume 101, Issue 10, Page 2571-2580, October 2026.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han, Ning Lin, Jinghang Xu, Sikui Wang, Jinglan Jin, Jia Shang, Yongning Xin, Youwen Tan, Dazhi Zhang, Jinlin Hou, Ping An, Wen Xie, Yujuan Guan, Qingfang Xiong, Hong Wu, Huiguo Ding, Yu Chen, Rongkuan Li, Zhili Wen, Mingqin Lu, Jinhui Yang, Zhongyin Zhou, Yongjian Zhou, Zujiang Yu, Kecan Lin, Wei Wang, Yan Huang, Yuemin Nan, Xinhua Luo, Rongshu Shi, Yi Kang, Tao Han, Shiyan Chen, Kai Wang, Yunfeng Shan, Jiaping Li, Pingguo Liu, Zheng Lu, Jun Chen, Zhen Liu, Liaoyun Zhang, Li Yang, Jifang Sheng, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu   +45 more
wiley   +1 more source