Results 251 to 260 of about 387,299 (303)

Hepatic encephalopathy due to non-cirrhotic portal hypertension associated with non-alcoholic steatohepatitis and chronic hepatitis B: a Case Report. [PDF]

Front Med (Lausanne)
Li H, Zhang J, Liu W, Liu Y, Yu X, Sun S.   +5 more
europepmc   +1 more source

Hypertriglyceridemia: Causes, Consequences, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Hypertriglyceridemia (HTG) arises from the interplay between genetic susceptibility and secondary or precipitating factors, leading to dysregulated triglyceride‐rich lipoprotein (TRL) metabolism. Increased TRL production and impaired clearance promote distinct risk phenotypes: accumulation of apolipoprotein B(apoB)‐containing TRL remnants contributes ...
Shanshan Qi, Weiwei Chen, Kunhao Chen, Song Yang, Sibo Wang, Tongtian Ni, Dan Xu, Enqiang Mao, Erzhen Chen, Ying Chen   +9 more
wiley   +1 more source

Quantitative longitudinal investigation of non-alcoholic steatohepatitis in mice by photoacoustic microscopy. [PDF]

Photoacoustics
Wei J, Zhang R, Jiang M, Gao L, Yu X, Liu X, Dai Y, Luo Q, Zhang Z, Yang X.   +9 more
europepmc   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Gardenia jasminoides fruit extract ameliorates non-alcoholic steatohepatitis with fibrosis by modulating inflammatory and fibrogenic pathways. [PDF]

PLoS One
Suttawong N, Witayavanitkul N, Chayanupatkul M, Wanpiyarat N, Werawatganone P, Siriviriyakul P, Werawatganon D.   +6 more
europepmc   +1 more source

Inhibition of COX‐2‐Mediated Arachidonic Acid Metabolism by FGF21‐PPARα Axis Alleviates Liver Steatosis

MedComm, Volume 7, Issue 10, October 2026.
Under physiological conditions, the FGF21‐PPARα axis restrains COX‐2 and maintains arachidonic acid (AA) metabolic homeostasis. During steatotic liver disease, ERK1/2 phosphorylation increases alongside adaptive FGF21/PPARα activation, which is insufficient to suppress COX‐2, leading to COX‐driven AA remodeling, PGE2 accumulation, inflammation, and ...
Guangsen Xu, Tingting Pan, Guiyun Wang, Feng Qiu, Junlin Leng, Qiyang Feng, Yongguo Xue, Ye Wang, Junwei Zheng, Huiying Lu, Bingyan Han, Suntao Wang, Jie Du, Jiaojian Lv, Baile Wang, Xuebo Pan   +15 more
wiley   +1 more source

HBV infection may sensitize patients to alcoholic steatohepatitis and non-alcoholic steatohepatitis. [PDF]

Gastroenterol Rep (Oxf)
Wang H.
europepmc   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Ultrafine garlic powder alleviates non-alcoholic steatohepatitis by inhibiting hepatocyte ferroptosis and modulating ERK-dependent oxidative stress. [PDF]

Front Pharmacol
Yu J, Shao N, Yang J, Yang L, Hong K, Chen Y, Zhao X, Yu H, Zhang T, Dong J.   +9 more
europepmc   +1 more source

Drug‐Induced Liver Injury During Treatment With Tocilizumab: A Case Report of an Atypical Pattern Lesion

Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.
ABSTRACT Tocilizumab is an interleukin‐6 (IL‐6) receptor antagonist indicated for various rheumatologic conditions. While hepatotoxicity is a recognized adverse effect, it predominantly manifests as hepatocellular injury. We report a rare case of drug‐induced liver injury (DILI) presenting with a cholestatic pattern and cholangitis features in a 75 ...
Louis‐Edmond Barbaro, Nouha Ben Othman, Delphine Viard, Fanny Rocher, Elliot Ewig, Raja Mroue, Claire Amigues, Alexandre O. Gérard   +7 more
wiley   +1 more source