Results 81 to 90 of about 325,826 (332)

A prefrontal-bed nucleus of the stria terminalis circuit limits fear to uncertain threat

open access: yeseLife, 2020
In many cases of trauma, the same environmental stimuli that become associated with aversive events are experienced on other occasions without adverse consequence.
Lucas R Glover   +10 more
doaj   +1 more source

Naloxone precipitated withdrawal increases dopamine release in the dorsal striatum of opioid dependent men

open access: yesTranslational Psychiatry, 2021
Dopamine (DA) neurotransmission is critical in the neurobiology of reward and aversion, but its contribution to the aversive state of opioid withdrawal remains unknown in humans.
Ehsan Shokri-Kojori   +2 more
doaj   +1 more source

Analysis of aminophospholipid molecular species by high performance liquid chromatography.

open access: yesJournal of Lipid Research, 1989
A new method is described for the separation of individual molecular species of the aminophospholipids, phosphatidylethanolamine and phosphatidylserine. Trinitrobenzene-sulfonic acid was used to derivatize both aminophospholipids and the derivatives were
F Hullin, H Y Kim, N Salem, Jr
doaj   +1 more source

Leverage and Alcohol Addiction [PDF]

open access: yes, 2012
This paper confronts the question of whether messages can be diluted or even contradicted by the format in which they are delivered through a textual analysis of the TNT procedural drama Leverage, examining the portrayal of alcoholism in the program. The
Gallagher, Tom
core   +1 more source

Progress of non‐motor symptoms in early‐onset Parkinson's disease

open access: yesIbrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang   +5 more
wiley   +1 more source

Auto-FPFA: An Automated Microscope for Characterizing Genetically Encoded Biosensors

open access: yesScientific Reports, 2018
Genetically encoded biosensors function by linking structural change in a protein construct, typically tagged with one or more fluorescent proteins, to changes in a biological parameter of interest (such as calcium concentration, pH, phosphorylation ...
Tuan A. Nguyen   +3 more
doaj   +1 more source

Former heroin-dependent alcohol use disorder patients. prevalence, addiction history and clinical features [PDF]

open access: yes, 2015
Aims: To examine the prevalence of former heroin dependence (FHA) in Alcohol Use Disorder (AUD) patients; to compare the clinical characteristics of FHA-AUD patients versus AUD patients without any past use of heroin at alcohol treatment entry; to ...
Ceccanti, Mauro   +3 more
core   +1 more source

24R,25(OH)2D3 regulates tumorigenesis in estrogen sensitive laryngeal cancer cells via membrane‐associated receptor complexes in ER+ and ER− cells

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Estrogen receptors likely influence the development of laryngeal cancer and are of particular interest in regard to their relationship with the vitamin D metabolite 24R,25(OH)2D3. In this study the authors examined interactions between 24R,25(OH)2D3 and estrogen‐responsive laryngeal tumorigenesis.
Cydney D. Dennis   +10 more
wiley   +1 more source

Longitudinal Associations Between Early Noncoital Sexual and Romantic Behaviors and Adolescent Depressive Symptoms

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Introduction Research has linked early intercourse and romantic relationships to increased depressive symptoms, especially for female adolescents. However, less is known about the ways in which early noncoital sexual behaviors are associated with mental health.
Sara A. Vasilenko   +4 more
wiley   +1 more source

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