Results 61 to 70 of about 232,048 (303)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Alkylation of amines with allylic alcohols and deep eutectic solvents as metal-free and green catalyst [PDF]
, 2023 A novel approach for the allylic alkylation of anilines, hydrazides and indole derivatives by the direct use of allylic alcohols is described under very mild conditions, such as room temperature and using sustainable deep eutectic solvents (DESs).
Raquel, P. Herrera +2 more
core +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Free-Radical Deoxygenative Amination of Alcohols via Copper Metallaphotoredox Catalysis [PDF]
Although alcohols are among the most abundant chemical feedstock, they remain vastly underutilized as coupling partners in transition metal catalysis.
William P., Carson II +6 more
core +1 more source
Alcohols and bio-alcohols steam and autothermal reforming in a membrane reactor
, 2014 Publisher Copyright: © 2015 by Nova Science Publishers, Inc. All rights reserved.Considerable work has been reported concerning catalytic steam reforming, partial oxidation and oxidative steam reforming (autothermal reforming) aimed at hydrogen ...
Hedayati, Ali, Llorca, Jordi
core +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
Oxidation of Alcohols in Continuous Flow with a Solid Phase Hypervalent Iodine Catalyst [PDF]
, 2023 One of the most useful transformations in the synthetic chemist arsenal is the oxidation of alcohols to their corresponding carbonyl congeners. Despite its seemingly straightforward nature, this transformative reaction predominantly relies on the use of ...
Kathrin, Bensberg +4 more
core +2 more sources
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source