Rational Design of Conjugated Phenylpropanoid-Polyene Hybrids: Density Functional Theory Insights into Antiradical and Optical Properties. [PDF]
Int J Mol SciMolski M.
europepmc +1 more source
Angewandte Chemie, EarlyView.Cyclopropene fatty acids have been made that allow the study of fatty acid uptake in complex mixtures of immune cells with single cell resolution and combined with metabolic and proteomic analysis so that for the first time nutrient uptake can be correlated to the phenotype of single immune cell.
Luuk Reinalda +14 more
wiley +1 more source
Homeostasis of Molybdenum, Xanthine Oxidase and Aldehyde Oxidase Activity Levels in the Livers of Patients with End-Stage Liver Failure and Healthy Controls. [PDF]
Int J Mol SciAdamus JP +7 more
europepmc +1 more source
Reenvisioning the De Mayo Reaction: A Boron‐Enabled Cycloaddition Approach
Angewandte Chemie, EarlyView.An oxa‐boracycle conformational lock strategy enables photocatalytic [2+2] cycloaddition to afford densely substituted cyclobutylboronates. The conformational constraint suppresses triplet relaxation and promotes productive bimolecular reactivity.
Neetu Sharma +5 more
wiley +1 more source
Dynamically assembled photochromic cages operational in water with visible light. [PDF]
Nat CommunSchäfer V +3 more
europepmc +1 more source
Angewandte Chemie, EarlyView.Die Kontrolle biologischer Systeme mit organischen Chromophoren hat sich zu einer vielversprechenden Strategie entwickelt und findet Anwendung von der chemischen Biologie bis hin zur Medizin. Die Komplexität von In‐vivo‐Systemen lässt sich jedoch nicht mit nur einer einzigen Lichtwellenlänge adäquat abbilden.
Nadja A. Simeth
wiley +1 more source
Fragment-Based Online OzESI-MS, NMR, and Computational DP4+/DFT Approaches to the Characterization of the Putative Biosynthetic Lipid Precursor of Atkamine from Alaskan <i>Latrunculia</i> Sponges. [PDF]
ACS OmegaBenjamin MM +11 more
europepmc +1 more source
Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis
Angewandte Chemie, EarlyView.Understanding stereoselective biotransformations has implications for predicting drug disposition and response and may also inspire novel biocatalytic and biomimetic strategies to address challenges in metabolite and API synthesis. ABSTRACT Chirality is an important determinant of drug action, as enantiomers can exhibit markedly different ...
Grace A. Okunlola, Godwin A. Aleku
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Promiscuity‐Guided Enzyme Evolution via Substrate Multiplexed Screening
Angewandte Chemie, EarlyView.Through historical context and recent examples, this Minireview summarizes the strengths, limitations, and practical considerations for the implementation of substrate multiplexed screening (SUMS) in enzyme evolution. ABSTRACT An enzyme's ability to react with diverse substrates while maintaining high yield and selectivity, termed “substrate ...
Holly A. Weilbaker +3 more
wiley +1 more source
Programmable Solid‐Electrolyte Interfaces for Efficient and Selective Electrochemical Hydrogenations
Angewandte Chemie, EarlyView.Poly(ionic liquid) binders are shown to actively control the electrode microenvironment, strongly enhancing electrochemical hydrogenation compared to traditional binders. The work redefines the binder as an active component of catalytic electrode design, reshaping local potential gradients and interfacial ion distribution to modulate adsorbed H ...
Anastasios Orestis Grammenos +9 more
wiley +1 more source