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Role of Aldehyde Dehydrogenases in Physiopathological Processes.
Chemical Research in Toxicology, 2019Many different diseases are associated with oxidative stress. One of the main consequences of oxidative stress at the cellular level is lipid peroxidation, from which toxic aldehydes may be generated.
J. Rodríguez-Zavala +3 more
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Chiral Aldehyde Catalysis for the Catalytic Asymmetric Activation of Glycine Esters.
Journal of the American Chemical Society, 2018Chiral aldehyde catalysis is uniquely suitable for the direct asymmetric α-functionalization of N-unprotected amino acids, because aldehydes can reversibly form imines. However, there have been few successful reports of these transformations.
Wei Wen +6 more
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Exploration of C-H Transformations of Aldehyde Hydrazones: Radical Strategies and Beyond.
Accounts of Chemical Research, 2018The chemistry of hydrazones has gained great momentum due to their involvement throughout the evolution of organic synthesis. Herein, we discuss the tremendous developments in both the methodology and application of hydrazones.
Pan Xu +3 more
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Angewandte Chemie, 2014
An organocatalytic azide-aldehyde [3+2] cycloaddition (organo-click) reaction of a variety of enolizable aldehydes is reported. The organo-click reaction is characterized by a high rate and regioselectivity, mild reaction conditions, easily available ...
Dhevalapally B. Ramachary +2 more
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An organocatalytic azide-aldehyde [3+2] cycloaddition (organo-click) reaction of a variety of enolizable aldehydes is reported. The organo-click reaction is characterized by a high rate and regioselectivity, mild reaction conditions, easily available ...
Dhevalapally B. Ramachary +2 more
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Chemical Communications, 2014
We report herein a new approach, which combines fast nucleophilic addition of H2S to an aldehyde group and the subsequent intramolecular thiolysis of dinitrophenyl ether, and can be used to develop efficient and effective H2S probes.
Zijun Huang +4 more
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We report herein a new approach, which combines fast nucleophilic addition of H2S to an aldehyde group and the subsequent intramolecular thiolysis of dinitrophenyl ether, and can be used to develop efficient and effective H2S probes.
Zijun Huang +4 more
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Amine-functionalized porous silicas as adsorbents for aldehyde abatement.
ACS Applied Materials and Interfaces, 2013A series of aminopropyl-functionalized silicas containing of primary, secondary, or tertiary amines is fabricated via silane-grafting on mesoporous SBA-15 silica and the utility of each material in the adsorption of volatile aldehydes from air is ...
A. Nomura, Christopher W. Jones
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α-Oxo aldehyde or glyoxylyl group chemistry in peptide bioconjugation.
Bioconjugate chemistry, 2013Since the 1990s, α-oxo aldehyde or glyoxylic acid chemistry has inspired a vast array of synthetic tools for tailoring peptide or protein structures, for developing peptides endowed with novel physicochemical properties or biological functions, for ...
O. El‐Mahdi, O. Melnyk
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Aldehyde‐Catalyzed Transition Metal‐Free Dehydrative β‐Alkylation of Methyl Carbinols with Alcohols
, 2013Different to the borrowing hydrogen strategy in which alcohols were activated by transition metal-catalyzed anaerobic dehydrogenation, the direct addition of aldehydes was found to be an effective but simpler way of alcohol activation that can lead to ...
Qing Xu, Jianhui Chen, Quan Liu
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