Results 251 to 260 of about 573,333 (386)

Inhalation of the reactive aldehyde acrolein promotes antigen sensitization to ovalbumin and enhances neutrophilic inflammation

, 2015
Edmund O’Brien, Page C. Spiess, Aida Habibovic, Milena Hristova, Robert A. Bauer, Matthew J. Randall, Matthew E. Poynter, Albert van der Vliet   +7 more
openalex   +1 more source

Novel Antifungal Scaffold Targeting Tubulin Overcomes Sclerotinia Sclerotiorum Resistance

Advanced Science, EarlyView.
Addressing pesticide resistance, novel chromone‐acylhydrazone hybrids targeting fungal tubulin are synthesized. Compound G24 potently inhibited S. sclerotiorum (EC50 = 0.21µg mL−1) and demonstrated enhanced field performance via microencapsulation, offering a sustainable strategy against resistance and for global food security.
Lihui Shao, Xianqun Hu, Ying Wu, Xiang Zhou, Bo Zhang, Song Yang   +5 more
wiley   +1 more source

Targeted high-resolution sensing of volatile organic compounds by covalent nanopore detection. [PDF]

Nat Commun
McGivern LE, Lim ZH, Yuan Y, Bo Z, Wu G, Bayley H, Qing Y.   +6 more
europepmc   +1 more source

High‐Performance Quasi‐Solid‐State Calcium‐Ion Batteries from Redox‐Active Covalent Organic Framework Electrolytes

Advanced Science, EarlyView.
Quasi‐solid‐state calcium‐ion batteries (QSSCIBs) employing redox‐active covalent organic frameworks (COFs) based electrolytes are developed. The COFs’ crystalline porous structures, featuring aligned carbonyl groups, enabled high Ca2⁺ conductivity, supported by molecular dynamics simulations of the ion transport mechanism.
Zhuoyu Yin, Jixin Wu, Ye Tian, Yufei Yuan, Muhua Gu, Lei Cheng, Yanming Wang, Yoonseob Kim   +7 more
wiley   +1 more source

Unraveling the metabolic potential and roles of reductases in the omicsynin biosynthetic gene cluster. [PDF]

Nat Prod Bioprospect
Li Y, Fu J, Sun H, Du Y, Si S, Li Y, Li X, Jiang J, Hong B.   +8 more
europepmc   +1 more source

Flavouring Group Evaluation 216: alpha, beta‐Unsaturated aldehydes from chemical subgroup 3.3 of FGE.19: 2‐Phenyl‐2‐alkenals

, 2009
European Food Safety Authority (EFSA)
openalex   +1 more source

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

2-Hydroxy-4-Methoxybenzaldehyde (2H4MB): Integrating Cell Culture, Metabolic Engineering, and Intelligent Genome Editing. [PDF]

Int J Mol Sci
Firdaus F, Yadav V, Ramakrishnan M, Wasi A, Ganie IB, Upadhyay A, Shahzad A, Ahmad Z.   +7 more
europepmc   +1 more source

Aldehyde dehydrogenase-2 regulates nociception in rodent models of acute inflammatory pain

Science Translational Medicine, 2014
V. Zambelli, E. Gross, Che-Hong Chen, V. Gutierrez, Y. Cury, D. Mochly‐Rosen   +5 more
semanticscholar   +1 more source

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source