Results 41 to 50 of about 228,734 (312)
Danishefsky’s Diene vs Rawal’s Diene in [4+2] Hetero-Diels-Alder Reactions with Aldehydes
Журнал органічної та фармацевтичної хіміїThe Diels-Alder reaction remains one of the most versatile and widely employed cycloaddition strategies in synthetic organic chemistry. The development of functionalized dienes, particularly Danishefsky’s diene (DD) and Rawal’s diene (RD), has ...
Oleksii I. Shamrai +1 more
doaj +1 more source
mSystems, 2019 Vanillin (4-hydroxy-3-methoxybenzaldehyde) is an economically important flavor compound that can be made in bacterial cell factories, but toxicity is a major problem for cells producing this aromatic aldehyde.
Calum A. Pattrick +5 more
doaj +1 more source
TRP Channels as Sensors of Aldehyde and Oxidative Stress
Biomolecules, 2021 The transient receptor potential (TRP) cation channel superfamily comprises more than 50 channels that play crucial roles in physiological processes. TRP channels are responsive to several exogenous and endogenous biomolecules, with aldehydes emerging as
Katharina E. M. Hellenthal +3 more
doaj +1 more source
A Prodrug Strategy for the In Vivo Imaging of Aldehyde Dehydrogenase Activity
, 2022 Therapy resistance is one of the biggest challenges facing clinical oncology. Despite a revolution in new anti-cancer drugs targeting multiple components of the tumour microenvironment, acquired or innate resistance frequently blunts the efficacy of ...
Raul , Pereira +5 more
core +1 more source
Aldehyde-Terminated Self-Assembled Monolayers on Gold: Immobilization of Amines onto Gold Surfaces
, 2016 Aldehyde-Terminated Self-Assembled Monolayers on Gold: Immobilization of Amines onto Gold ...
David C. Myles (2338201) +2 more
core +1 more source
ALDH2 mediates 5-nitrofuran activity in multiple species
, 2012 Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs. 5-nitrofurans are a class of pro-drugs widely used to treat bacterial and trypanosome infections, but despite relative ...
Spitzer, Michaela +33 more
core +1 more source
Identification of Key Residues for Enzymatic Carboxylate Reduction
Frontiers in Microbiology, 2018 Carboxylate reductases (CARs, E.C. 1.2.1.30) generate aldehydes from their corresponding carboxylic acid with high selectivity. Little is known about the structure of CARs and their catalytically important amino acid residues.
Holly Stolterfoht +10 more
doaj +1 more source
, 2016 Novel tetra-N-confused cyclohexapyrrole is synthesized for the first time via condensation of tripyrrinone-aldehyde with bis(2,4-dimethylpyrrole-3-yl)methane in the presence of p-toluenesulfonic acid monohydrate.
Yi Zhang (9093) +5 more
core +1 more source
, 2023 Durch Umsetzung von Fulvenen mit Phosphoroxychlorid in Dimethylformamid erhält man in guten Ausbeuten Fulven-aldehyde, von denen bisher kein Vertreter bekannt ...
Hafner, Klaus, Vöpel, K. H.
core +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source