Results 41 to 50 of about 256,760 (299)

Synthesis, spectroscopic characterization and pharmacological evaluation of oxazolone derivatives [PDF]

open access: yesJournal of the Serbian Chemical Society, 2013
A series of 4-aryl methylidene-2-phenyl/methyl-5-(4H)-oxazolone derivatives (2-7) have been synthesized using the reported method by condensation of aldehydes with N-benzoyl / N-acetyl glycine in the presence of zinc oxide as a catalyst and acetic ...
Fareed Ghulam   +7 more
doaj   +1 more source

Biological Role of Pazopanib and Sunitinib Aldehyde Derivatives in Drug-Induced Liver Injury

open access: yesMetabolites, 2022
Tyrosine kinase inhibitors pazopanib and sunitinib are both used to treat advanced renal cell carcinoma but expose patients to an increased risk of hepatotoxicity.
Maud Maillard   +9 more
doaj   +1 more source

Microwave-Assisted Three Component Cyclocondensation Reaction: A Facile Synthesis of Highly Functionalized Cyclohexene Derivatives [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2007
Microwave-assisted three component cyclocondensation reactions of aldehydes, amides and dienophiles in the presence of acetic anhydride and para-toluenesulfonic acid as a catalyst to afford the highly substituted cyclohexene derivatives, in relatively ...
Ahmad Shaabani, Peiman Mirzaei
doaj  

Lipid Peroxidation Produces a Diverse Mixture of Saturated and Unsaturated Aldehydes in Exhaled Breath That Can Serve as Biomarkers of Lung Cancer—A Review

open access: yesMetabolites, 2022
The peroxidation of unsaturated fatty acids is a widely recognized metabolic process that creates a complex mixture of volatile organic compounds including aldehydes.
Saurin R. Sutaria   +5 more
doaj   +1 more source

Aldehyde-Terminated Self-Assembled Monolayers on Gold:  Immobilization of Amines onto Gold Surfaces

open access: yes, 2016
Aldehyde-Terminated Self-Assembled Monolayers on Gold:  Immobilization of Amines onto Gold ...
David C. Myles (2338201)   +2 more
core   +1 more source

Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis

open access: yesFrontiers in Neurology, 2018
Demyelination and axonal injury are the key pathological processes in multiple sclerosis (MS), driven by inflammation and oxidative stress. Acrolein, a byproduct and instigator of oxidative stress, has been demonstrated as a neurotoxin in experimental ...
Melissa Tully   +14 more
doaj   +1 more source

Annotation of 1350 Common Genetic Variants of the 19 ALDH Multigene Family from Global Human Genome Aggregation Database (gnomAD)

open access: yesBiomolecules, 2021
Human aldehyde dehydrogenase (ALDH) is a multigene family with 19 functional members encoding a class of diverse but important enzymes for detoxification or biotransformation of different endogenous and exogenous aldehyde substrates. Genetic mutations in
Che-Hong Chen   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Catalytic Reductive Amination of Aromatic Aldehydes on Co-Containing Composites

open access: yesChemistry, 2023
The performance of a series of cobalt-based composites in catalytic amination of aromatic aldehydes by amines in the presence of hydrogen as well as hydrogenation of quinoline was studied.
Vladyslav V. Subotin   +7 more
doaj   +1 more source

Tetra-N-confused Cyclohexapyrrole:  The Unusual Product Formed by Condensation of 3,3‘-Dipyrromethane with Tripyrrin-aldehyde

open access: yes, 2016
Novel tetra-N-confused cyclohexapyrrole is synthesized for the first time via condensation of tripyrrinone-aldehyde with bis(2,4-dimethylpyrrole-3-yl)methane in the presence of p-toluenesulfonic acid monohydrate.
Yi Zhang (9093)   +5 more
core   +1 more source

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