Results 141 to 150 of about 329,736 (281)

Editorial: Aldehyde dehydrogenase in clinical settings: Potential biomarker and therapeutic target in solid tumors

Frontiers in Medicine, 2023
Beatrice Aramini, Valentina Masciale
doaj   +1 more source

Comparative Analysis of Alcohol and Aldehyde Dehydrogenase Activities in Prostate Cancer and Benign Prostatic Hyperplasia. [PDF]

J Clin Med
Nowiński AR, Jelski W, Skrodzka M, Mroczko B, Gryko M, Orywal K.   +5 more
europepmc   +1 more source

Translating gut microbiome research into therapies for type 1 diabetes

Experimental Physiology, EarlyView.
Abstract Type 1 diabetes (T1D) is characterised by the loss of functional pancreatic β‐cells, for which lifelong insulin therapy remains the standard of care. Given that the gut microbiome can influence host health and that shifts in gut microbial profiles have been observed in T1D, growing interest has emerged in the role of the gut microbiome in T1D,
Shanti P. Kok, Max Nieuwdorp, Elena Rampanelli   +2 more
wiley   +1 more source

Protective role of aldehyde dehydrogenase 2 in retinal pigment epithelium cells with CoCl₂-induced hypoxic injury: an in-vitro study. [PDF]

BMC Pharmacol Toxicol
Zhang S, Chen G, Xiao L, Dong J, Chao Y, Xia Y, Long P, Yan W.   +7 more
europepmc   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

The Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray, Girish Halemirle, Beatriz Ferrán, Hadyn Rose, Traci L. Redwine, Sophia Pham, Bo Hagy, Atul Pranay, Jennifer Giorgione, Stacy A. Hussong, Veronica Galvan, Kenneth Humphries, Holly Van Remmen, Mike Kinter, William E. Sonntag, Pankaj K. Singh, Carlos Manlio Díaz‐García   +16 more
wiley   +1 more source

Excessive training does not induce mitochondrial dysfunction or impair insulin signalling within skeletal muscle

The Journal of Physiology, EarlyView.
Abstract figure legend Three weeks of overtraining in trained endurance athletes reduced exercise performance without impairing glucose tolerance. In skeletal muscle, overtraining was associated with increased expression of lipid metabolism‐related proteins, enhanced mitochondrial biogenesis and preserved insulin signalling, despite elevated oxidative ...
Geneviève J. DesOrmeaux, Henver S. Brunetta, Pierre‐Andre Barbeau, Alexandra M. Coates, Christopher Pignanelli, Fasih A. Rahman, Jamie F. Burr, Graham P. Holloway   +7 more
wiley   +1 more source

CYSTAMINE AND HOMOCYSTAMINE OXIDATION IN A COUPLED REACTION CATALYZED BY DIAMINEOXIDASE AND ALDEHYDE DEHYDROGENASE

, 1994
Cystamine and homocystamine are oxidatively monodeaminated by lentil seedling amineoxidase and the aminoaldehydes arising from this reaction are readily oxidized to the corresponding omega-aminoacids by bakers yeast aldehyde dehydrogenase.
CINI, Chiara, BLARZINO, Carla, COCCIA, Raffaella, C. Foppoli, DE MARCO, Carlo   +4 more
core  

Demonstration of beat‐to‐beat, on‐demand ATP synthesis in ventricular myocytes reveals sex‐specific mitochondrial and cytosolic dynamics

The Journal of Physiology, EarlyView.
Abstract figure legend Beat‐locked mitochondrial ATP transients reveal modular, sex‐specific bioenergetic control during excitation–contraction coupling. A, each action potential activates L‐type CaV1.2 channels, producing a Ca2+ influx that triggers ryanodine receptors (RyR2) and elicits SR Ca2+ release.
Paula Rhana, Collin Matsumoto, L. Fernando Santana   +2 more
wiley   +1 more source

Identification of mitochondria-associated hub genes related to alcohol-associated liver fibrosis progression in aldehyde dehydrogenase 2 deficiency. [PDF]

Front Physiol
Zhang F, Gao Y.
europepmc   +1 more source

Short‐Term Effect of Fishmeal‐Free Feed Formulation on Growth Performance, Feed Efficiency and Transcriptomic Profile of Hypothalamus and Liver in Atlantic Salmon

Aquaculture, Fish and Fisheries, Volume 6, Issue 6, December 2026.
Transcriptomic responses of the hypothalamus and liver were compared in Atlantic salmon fed fishmeal or fishmeal‐free diets under simulated Tasmanian summer conditions. Fishmeal‐free feeding reduced growth performance, downregulated hypothalamic orexigenic pathways and increased hepatic lipogenesis. ABSTRACT Atlantic salmon (Salmo salar) aquaculture is
Maximiliano M. Canepa, Mechiel L. J. Wetering, Gianluca Amoroso, Jennie de Haan, Wesley van den Herik, Rhys Hauler, Chris G. Carter   +6 more
wiley   +1 more source