Results 151 to 160 of about 329,736 (281)

Glycation of Salivary Aldehyde Dehydrogenase: Emerging Molecular Mechanisms and Clinical Implications in Oral Disease. [PDF]

Life (Basel)
Khan MA, Younus H.
europepmc   +1 more source

Cloning, heterologous expression, purification, and kinetic analysis of aldehyde dehydrogenase 4 of Saccharomyces cerevisiae.

, 2010
碩士酵母菌醛類去氫酶4（YOR374w）是一種位在粒線體內的去氫酶，需要鉀離子的活化，以及NAD+或NADP+當輔酶，在乙醇的代謝途徑扮演很重要的角色，尤其是以乙醇當碳源的環境下。為了了解醛類去氫酶對於其他不同代謝途徑是否有影響，經由選殖出正確ALD4基因，再利用大腸桿菌大量的表現出ald4p，透過管柱層析純化之後，對許多不同的受質做活性分析。在酵母菌的泛酸生合成途徑中，3-aminopropanal氧化成beta-alanine是重要的一個反應，而glycine betaine是一種滲透壓保護劑 ...
陳俊傑; Chen, Jyun-jie
core  

Discovery of a First‐in‐Class Dual‐Function TLX Activator by Microscale Library Synthesis and Direct‐to‐Biology Screening

Angewandte Chemie Novit, Volume 2, Issue 4, December 2026.
The transcription factor tailless (TLX) is an orphan nuclear receptor thought to maintain neural and retinal stem cell populations in a proliferating state to enable regeneration. Ligands to study TLX modulation were lacking. We developed a potent TLX agonist capable of activating TLX's transcriptional repressor and activator properties in an evolution‐
Tanja Stiller, Romy Busch, Giuseppe Faudone, Felia C. Haffelder, Jan Vietor, Arthur Kardanov, Úrsula López‐García, Arne Hackspacher, Georg Höfner, Vasily Morozov, Susanne F. Koch, Julian A. Marschner, Daniel Merk   +12 more
wiley   +1 more source

Biosensor-guided directed evolution of aldehyde dehydrogenase for improved adipic acid production from caprolactone. [PDF]

J Biol Eng
Kim H, Moon SY, Park JY, Baek SH, Sung BH, Lee JW, Lee JY, Noh MH.   +7 more
europepmc   +1 more source

Aldehyde Dehydrogenase [PDF]

, 2020
openaire   +1 more source

Comparative proteomic analysis of bone marrow mononuclear cells and peripheral blood mononuclear cells for autologous therapeutic implantation in chronic wounds

Clinical and Translational Discovery, Volume 6, Issue 6, December 2026.
• Integrative evaluation with proteomic analysis of mononuclear cells (MNC) from bone marrow (BM) or peripheral blood (PB) sources for autologous cell implantation in patients with chronic wounds sheds light on molecular differences and clinical outcomes. • BM‐MNC and PB‐MNC exhibited distinct and source‐specific proteomic signatures.
Farina Mohamad Yusoff, Nor Azfa Johari, Masato Kajikawa, Sharifah Zakiah Syed Sulaiman, Harikrishna K R Nair, Sze‐Piaw Chin, Shinji Kishimoto, Tatsuya Maruhashi, S Fadilah S Abdul Wahid, Yukihito Higashi   +9 more
wiley   +1 more source

Aldehyde Dehydrogenase-2 Alleviates Septic Myocardial Injury by Inhibiting Caspase-11-Mediated Noncanonical Pyroptosis. [PDF]

Cardiovasc Ther
Liang H, He Y, Wang Y, Zhang R, Yu M, Ye H, Wang J, Gao Q.   +7 more
europepmc   +1 more source

Stem cell‐based platforms for cancer therapy: Biological mechanisms, therapeutic applications and clinical translation

Clinical and Translational Discovery, Volume 6, Issue 6, December 2026.
Stem cell platforms offer distinct therapeutic, supportive and research‐enabling applications in oncology. Haematopoietic stem cell transplantation is established for selected haematological malignancies. Engineered MSCs, NSCs and pluripotent stem cell‐derived products remain investigational anticancer platforms.
Ruba Altahla, Ye Lixiang, Mohammad Javad Mehran, Li Chaoyi, Mansoor Bolideei, Jamal Alshorman   +5 more
wiley   +1 more source

Aldehyde Dehydrogenase 2 Gene Polymorphism and Alcohol Consumption Are Associated With Nephrolithiasis in a Chinese Population. [PDF]

Mol Genet Genomic Med
Liu T, Lv YQ, Huang XL, Xie YL, Ye Y, Chen Y, Feng C, Wang QY, Mo ZN, Liao M, Li TY, Liao J.   +11 more
europepmc   +1 more source

Integrated Metabolic and Transcriptomic Profiles Furnish Insights to Flavonoid Variation in Dendrobium officinale From Different Areas in China

eFood, Volume 7, Issue 6, December 2026.
Zhejiang‐sourced D. officinale exhibits superior flavonoid content. Integrated metabolomic and transcriptomic analyses reveal key genes regulating flavonoid biosynthesis, elucidating the geographical impact on quality. ABSTRACT Dendrobium officinale (D.
Ziying Wang, Zhiwei Wang, Mengni Li, Tinghui Feng, Feng Yin, Xiaodan Zhang, Zongsuo Liang   +6 more
wiley   +1 more source