Aging Cell, Volume 25, Issue 5, May 2026.We developed a LASSO‐based approach to uncover a three‐layered “fan‐in fan‐out” network architecture for complex traits like yeast aging, showing that peripheral genes influence lifespan indirectly through master regulators, which converge on core functional modules (e.g., stress response, autophagy).
Meng Ma +12 more
wiley +1 more source
Expression of Aldehyde Dehydrogenase 1A1 in Relapse-Associated Cells in Acute Myeloid Leukemia. [PDF]
CellsCostello R +4 more
europepmc +1 more source
Fatty Aldehyde Dehydrogenase [PDF]
Journal of Biological Chemistry, 2004 Damien Demozay +6 more
openaire +1 more source
Re‐Evaluating Hot Mitochondria: Too Slow to Cool
Acta Physiologica, Volume 242, Issue 5, May 2026.ABSTRACT Aim Mito Thermo Yellow (MTY) is a mitochondrially targeted fluorophore that shows marked fluorescence quenching with increasing temperature, allowing for interrogating temperature dynamics in the mitochondria of live cells. Here we re‐evaluate published MTY fluorescence responses used to argue in favor of the ‘hot mitochondria’ concept; the ...
Jason R. Treberg, Ryan J. Mailloux
wiley +1 more source
Cloning and Functional Analysis of the Aldehyde Dehydrogenase Gene <i>VvALDH</i> in the IAA Synthesis Pathway of <i>Volvariella volvacea</i>. [PDF]
J Fungi (Basel)Mao M +9 more
europepmc +1 more source
Glucose Metabolism Regulating Colorectal Cancer Initiation and Progression
Cancer Science, Volume 117, Issue 5, Page 1199-1208, May 2026.Drugs and compounds targeting glycolysis in CRC and the mechanisms by which these drugs inhibit their respective targets. ABSTRACT Colorectal cancer (CRC) is one of the most common types of invasive cancer worldwide, which has the characteristics of poor curative effect and poor prognosis. Increasing evidence suggests that hyperactivated glucose uptake
Meiyi Lin, Junpeng Cui
wiley +1 more source
Mitochondrial aldehyde dehydrogenase restores the migratory capacity inhibited by high glucose-induced hyperosmolality. [PDF]
Sci RepHuang CC, Chen YL, Chien CL.
europepmc +1 more source
European Journal of Haematology, Volume 116, Issue 5, Page 604-614, May 2026.ABSTRACT Introduction Cryopreservation of peripheral‐blood‐derived hematopoietic stem and progenitor cells (PBSCs) has been used for decades, primarily for autologous transplantation. Now, in the era of new cellular therapies, the cryopreservation of allogeneic PBSCs may also become relevant.
Philipp Blüm +5 more
wiley +1 more source
Emerging Technologies for Biobutanol Production via Syngas Fermentation
GCB Bioenergy, Volume 18, Issue 5, May 2026.Biobutanol production from syngas is promising but limited by microbial energy conservation and gas–liquid mass transfer. This review integrates advances in cultivation control and bioreactor engineering with next‐generation biological tools including metabolic rewiring, co‐cultivation and chain elongation, and electro‐fermentation to enable carbon ...
Xuemei Wang +3 more
wiley +1 more source
Aldehyde Dehydrogenase 2 rs671 Polymorphism is Associated with Susceptibility of Coronary Atherosclerosis in Patients with Hypertension. [PDF]
Int J Gen MedHou H +5 more
europepmc +1 more source