Aldehyde dehydrogenase 2 rs671 a/A Genotype is Associated with an Increased Risk of Early Onset Coronary Artery Stenosis. [PDF]
Rao H +5 more
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Impact of the aldehyde dehydrogenase 2 (ALDH2) gene testing on alcohol drinking behaviors among the Chinese Han population: study protocol of a single-center, open-label, randomized, controlled clinical trial. [PDF]
Lu D +7 more
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Aldehyde Dehydrogenase-1A1 (ALDH1A1): The Novel Regulator of Chemoresistance in Pancreatic Cancer Cells. [PDF]
Duong HQ +7 more
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Dysregulation of cardiac mitochondrial aldehyde dehydrogenase 2: Studies in dogs with chronic heart failure. [PDF]
Gupta RC +5 more
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Correction to: Mitochondrial aldehyde dehydrogenase rescues against diabetic cardiomyopathy through GSK3β-mediated preservation of mitochondrial integrity and Parkin-mediated mitophagy. [PDF]
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Uncovering newly identified aldehyde dehydrogenase 2 genetic variants that lead to acetaldehyde accumulation after an alcohol challenge. [PDF]
Rwere F +10 more
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Mitochondrial Aldehyde Dehydrogenase 2 (ALDH2) Protects against Binge Alcohol-Mediated Gut and Brain Injury. [PDF]
Ray B +4 more
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HEPATIC ALDEHYDE DEHYDROGENASE AND ALCOHOLISM
The Lancet, 1982W J, Jenkins, K, Cakebread, K R, Palmer
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Aldehyde Inhibitors of Aldehyde Dehydrogenases
1999Aldehyde dehydrogenases catalyze aldehyde dehydrogenation as well as ester hydrolysis. Nitrate esters e.g. isosorbide nitrates and nitroglycerin inhibit the enzyme. Mechanism of inhibition which involves aldehyde dehydrogenase catalyzed formation of a reactive species (Mukerjee and Pietruszko, 1994), which inactivates the enzyme via covalent bond ...
R, Pietruszko +5 more
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Summary o 1. A soluble enzyme has been isolated from baker's yeast which catalyzes the reduction of pyridine nucleotides by several aldehydes. With acetaldehyde, the most rapidly utilized substrate, the oxidative product is acetic acid. A reverse reaction was not demonstrated. 2.
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