Results 11 to 20 of about 195,221 (99)
Chemical Research in Toxicology, 2004 NoAliphatic aldehydes have a high affinity toward aldehyde dehydrogenase activity but are relatively poor substrates of aldehyde oxidase and xanthine oxidase.
Panoutsopoulos, Georgios I. +4 more
core +5 more sources
Pharmacology, 2005 NoAromatic aldehydes are good substrates of aldehyde dehydrogenase activity but are relatively poor substrates of aldehyde oxidase and xanthine oxidase.
Panoutsopoulos, Georgios I. +3 more
core +4 more sources
Studies on the Mechanism of Aldehyde Oxidase and Xanthine Oxidase [PDF]
The Journal of Organic Chemistry, 2008 DFT calculations support a concerted mechanism for xanthine oxidase and aldehyde oxidase hydride displacement from the sp(2) carbon of 6-substituted 4-quinazolinones. The variations in transition state structure show that C-O bond formation is nearly complete in the transition state and the transition state changes are anti-Hammond with the C-H and C-O
ALFARO, Joshua F, JONES, Jeffrey P
openaire +3 more sources
Drosophila Melanogaster as a Model for Molybdo-Flavoenzyme Mediated Protection against Chemical and Physical Stress [PDF]
Aldehyde oxidase (AO) and xanthine oxidoreductase (XOR) are molybdo-flavoenzymes (MFEs) involved in the oxidation of hundreds of endogenous and exogenous aldehydes and N-heterocyclic compounds many of which are drugs, vitamins and environmental ...
Al Salhen, Khaled S
core +3 more sources
, 2022 Xenobiotic-metabolizing enzymes (XMEs) expressed in the olfactory epithelium (OE) are known to metabolize odorants. Aldehyde oxidase (AOX) recognizes a wide range of substrates among which are substrates with aldehyde groups. Some of these AOX substrates
Sanoh, Seigo +17 more
core +1 more source
Research progress of aldehyde oxidases in plants
PeerJ, 2022 Plant aldehyde oxidases (AOs) are multi-functional enzymes, and they could oxidize abscisic aldehyde into ABA (abscisic acid) or indole acetaldehyde into IAA (indoleacetic acid) as the last step, respectively. AOs can be divided into four groups based on their biochemical and physiological functions.
Jun Wu +4 more
openaire +3 more sources
Aldehyde oxidase 1 gene is regulated by Nrf2 pathway [PDF]
, 2012 Aldehyde oxidase is a member of the molybd-flavo enzyme family that catalyzes the hydroxylation of heterocycles and the oxidation of aldehydes into corresponding carboxylic acids.
Ohno, Takashi +5 more
core +1 more source
, 2014 Aldehyde oxidase is molybdo-flavoenzyme involved in the oxidation of hundreds of endogenous and exogenous and N-heterocyclic compounds and environmental pollutants.
Khaled S. Al Salhen
core +1 more source
The mammalian aldehyde oxidase gene family [PDF]
Human Genomics, 2009 Aldehyde oxidases (EC 1.2.3.1) are a small group of structurally conserved cytosolic proteins represented in both the animal and plant kingdoms. In vertebrates, aldehyde oxidases constitute the small sub-family of molybdo-flavoenzymes, along with the evolutionarily and structurally related protein, xanthine oxidoreductase.
Garattini Enrico +2 more
openaire +3 more sources
Metabolism of cryptolepine and 2-fluorocryptolepine by aldehyde oxidase
, 2011 NoObjectives To investigate the metabolism of cryptolepine and some cryptolepine analogues by aldehyde oxidase, and to assess the implications of the results on the potential of cryptolepine analogues as antimalarial agents.
Wheelhouse, Richard T. +5 more
core +1 more source