Redox Biology, 2023 The conversion of xanthine dehydrogenase (XDH) to xanthine oxidase (XO) occurs only in mammalian species. In fresh bovine milk, the enzyme exists predominantly as the oxidase form, in contrast to various normal organs where it is found primarily as the ...
Teruo Kusano +2 more
exaly +3 more sources
Mechanism of xanthine oxidase in flap ischemia-reperfusion injury and advances in targeted therapy: a mini review [PDF]
Frontiers in PhysiologyIschemia-reperfusion injury in flaps refers to a cascade of pathophysiological reactions that aggravate tissue damage or even cause necrosis. During the period of ischemia followed by restored blood reperfusion, a burst of reactive oxygen species is ...
Weidong Jia, Xin Wei, Xu Gong
doaj +2 more sources
TISSUE DISTRIBUTION OF THE MOLYBDENUM HYDROXYLASES, ALDEHYDE OXIDASE AND XANTHINE OXIDASE, IN NAJDI SHEEP [PDF]
Assiut Veterinary Medical Journal, 2005 The Activity of the molybdenum hydroxylases, aldehyde oxidase and xanthine oxidase were determined in ammonium sulfate fractions prepared from sheep liver, kidney, lung, small intestines, spleen and heart. In all examined tissues, aldehyde oxidase levels
YOUSUF ABDULMALIK AL-TAYIB
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Food Chemistry: X, 2022 Pickled radish is a general source of natural bioactive compounds that include phenols. Here, we used molecular docking, fluorescence quenching, circular dichroism spectroscopy and molecular dynamics simulations to identify potential inhibitors against ...
Xiaoze Liu +7 more
doaj +1 more source
Implication of changes in xanthine oxidase activity following hemodialysis
BMC Nephrology, 2023 Background Xanthine oxidase activity has a key role in the development of oxidative stress and progression of cardiovascular diseases. However, the change of xanthine oxidase activity following hemodialysis and its prognostic impact remain uncertain ...
Hayato Fujioka +5 more
doaj +1 more source
Xanthine oxidase inhibitory activity of Arcangelisia flava
Acta Biochimica Indonesiana, 2022 Background: Hyperuricemia is characterized by elevated levels of uric acid in the blood, produced from its precursor's xanthine and hypoxanthine via xanthine oxidase.
Fatmawati +5 more
doaj +1 more source
Anti-gout potential of selected Malaysian local fruits [PDF]
, 2021 This study aimed to investigate the in vitro xanthine oxidase (XO) inhibitory activity and phytochemical content of guava, water rose apple, Malay gooseberry, pineapple and ambarella.
Abu Bakar +22 more
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Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]
, 2016 The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa +8 more
core +12 more sources
Neurobiology of Disease, 2021 Inflammation and oxidative stress contribute to the pathophysiology of diabetic neuropathy. According to recent evidence, the modulation of macrophage polarization in peripheral nerves represents a potential therapeutic target for diabetic neuropathy ...
Kazuhisa Takahashi +9 more
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Bioactivity-guided Isolation and Identification of Xanthine Oxidase Inhibitors from Morus alba Bark [PDF]
Journal of Advanced Pharmacy Research, 2020 Objectives: The objective of this research was isolation and evaluation of xanthine oxidase inhibitory effects of isolated substances from mulberry bark (Morus alba L.).
Hang Nguyen +3 more
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