Screening medicinal plant extracts for xanthine oxidase inhibitory activity
Objectives. The study aimed to test the ethanol extracts of ten medicinal plants for xanthine oxidase inhibitory activity.Methods. The degree of xanthine oxidase inhibitory activity was determined by measuring the absorbance spectrophotometrically at 290
A. C. Ha, Ch. D.P. Nguyen, T. M. Le
doaj +3 more sources
Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity [PDF]
Correction of human myeloid cell function is crucial for the prevention of inflammatory and allergic reactions as well as leukaemia progression. Caffeine, a naturally occurring food component, is known to display anti-inflammatory effects which have ...
Abooali, Maryam +8 more
core +5 more sources
Mechanism of xanthine oxidase in flap ischemia-reperfusion injury and advances in targeted therapy: a mini review [PDF]
Ischemia-reperfusion injury in flaps refers to a cascade of pathophysiological reactions that aggravate tissue damage or even cause necrosis. During the period of ischemia followed by restored blood reperfusion, a burst of reactive oxygen species is ...
Weidong Jia, Xin Wei, Xu Gong
doaj +2 more sources
Xanthine Oxidase-A Personal History. [PDF]
A personal perspective is provided regarding the work in several laboratories, including the author’s, that has established the reaction mechanism of xanthine oxidase and related enzymes.
Hille R.
europepmc +6 more sources
Pickled radish is a general source of natural bioactive compounds that include phenols. Here, we used molecular docking, fluorescence quenching, circular dichroism spectroscopy and molecular dynamics simulations to identify potential inhibitors against ...
Xiaoze Liu +7 more
doaj +1 more source
Implication of changes in xanthine oxidase activity following hemodialysis
Background Xanthine oxidase activity has a key role in the development of oxidative stress and progression of cardiovascular diseases. However, the change of xanthine oxidase activity following hemodialysis and its prognostic impact remain uncertain ...
Hayato Fujioka +5 more
doaj +1 more source
Xanthine oxidase inhibitory activity of Arcangelisia flava
Background: Hyperuricemia is characterized by elevated levels of uric acid in the blood, produced from its precursor's xanthine and hypoxanthine via xanthine oxidase.
Fatmawati +5 more
doaj +1 more source
Novel perspectives in redox biology and pathophysiology of failing myocytes: modulation of the intramyocardial redox milieu for therapeutic interventions - A review article from the Working Group of Cardiac Cell Biology, Italian Society of Cardiology [PDF]
The prevalence of heart failure (HF) is still increasing worldwide, with enormous human, social, and economic costs, in spite of huge efforts in understanding pathogeneticmechanisms and in developing effective therapies that have transformed this ...
Angelini, Annalisa +8 more
core +12 more sources
Anti-gout potential of selected Malaysian local fruits [PDF]
This study aimed to investigate the in vitro xanthine oxidase (XO) inhibitory activity and phytochemical content of guava, water rose apple, Malay gooseberry, pineapple and ambarella.
Abu Bakar +22 more
core +1 more source

