Results 31 to 40 of about 78,843 (311)

Exercise Training Ameliorates Renal Oxidative Stress in Rats with Chronic Renal Failure

open access: yesMetabolites, 2022
In patients with chronic kidney disease, exercise training with moderate intensity protects renal function and improves mortality. However, the mechanisms of the renal protective effects of exercise training in chronic kidney disease have not been ...
Seiko Yamakoshi   +4 more
doaj   +1 more source

Xanthine dehydrogenase/xanthine oxidase and oxidative stress [PDF]

open access: yesAGE, 1997
Xanthine dehydrogenase (XDH) and xanthine oxidase (XOD) are single-gene products that exist in separate but interconvertible forms. XOD utilizes hypoxanthine or xanthine as a substrate and O2 as a cofactor to produce superoxide (·O2 (-)) and uric acid.
H Y, Chung   +7 more
openaire   +2 more sources

Participation of reactive oxygen species in regulation of Са2+ - activated К + channels of erythrocytes

open access: yesБюллетень сибирской медицины, 2009
In this study, we investigated the effects of preincubation with the reactive oxygen species-generating system xanthine oxidase/xanthine on Ca2+-dependent potassium permeability of erythrocyte membrane. The increase of intracellular calcium concentration
O. A. Trubacheva   +6 more
doaj   +1 more source

An investigation of the antiplatelet effects of succinobucol (AGI-1067) [PDF]

open access: yes, 2016
Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. Given the importance of oxidant stress in modulating platelet–platelet and platelet–vessel wall interactions, the aim of this study was to establish if antioxidant ...
Gnanadesika, Sukanya   +3 more
core   +1 more source

Screening of methanol extracts of sixty plants from Kerman for their potential xanthine oxidase inhibitory activity [PDF]

open access: yesJournal of HerbMed Pharmacology, 2017
Introduction: Gout is a chronic metabolic disease in which xanthine oxidase plays a crucial role. Many natural compounds such as various flavonoids have been reported to have inhibitory effect on xanthine oxidase.
Ahmad Gholamhoseinian   +2 more
doaj  

Alcool e radicais livres de oxigénio.

open access: yesActa Médica Portuguesa, 1993
Oxygen free radicals may be generated during ethanol metabolization by cytochrome P450, or due to the formation of xanthine oxidase by ethanol effect on xanthine dehydrogenase.
M L Mira, C F Manso
doaj   +1 more source

Association of Xanthine Oxidase and Neutrophil Activation Marker Elastase in Preeclampsia: A Case-control Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: Preeclampsia is an obstetric emergency for both mother and the foetus with unknown aetiology. Delivery is the only effective way in the prompt management.
Ramya Rajshekar   +4 more
doaj   +1 more source

Optimization of extraction conditions of phytochemical compounds and anti-gout activity of euphorbia hirta l. (Ara Tanah) using response surface methodology and Liquid Chromatography-Mass Spectrometry (LC-MS) analysis [PDF]

open access: yes, 2019
Gout is a common disease affected most of the people due to the elevation of uric acid in the blood. Flavonoid and phenolic compounds are reported to exert the anti-gout activity of medicinal plants. Hence, this study aimed at optimizing the extraction
Abdullah, Norazlin   +4 more
core   +1 more source

Chemical Evidence for Potent Xanthine Oxidase Inhibitory Activity of Ethyl Acetate Extract of Citrus aurantium L. Dried Immature Fruits

open access: yesMolecules, 2016
Xanthine oxidase is a key enzyme which can catalyze hypoxanthine and xanthine to uric acid causing hyperuricemia in humans. Xanthine oxidase inhibitory activities of 24 organic extracts of four species belonging to Citrus genus of the family Rutaceae ...
Kun Liu   +7 more
doaj   +1 more source

Alleviation of Hyperuricemia by Strictinin in AML12 Mouse Hepatocytes Treated with Xanthine and in Mice Treated with Potassium Oxonate

open access: yesBiology, 2023
Hyperuricemia, an abnormally high level of blood uric acid, is a major risk factor for gout. Although xanthine oxidase inhibitors were clinically used to lower blood uric acid level, the concerned side effects restricted their utilization. In this study,
Kuo-Ching Huang   +8 more
doaj   +1 more source

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