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Reactivity of Enzyme Modification Reagents with Aldose Reductase and Aldehyde Reductase
1990Aldose reductase (EC 1.1.1.21) and aldehyde reductase (EC 1.1.1.2) are members of a broad family of NADPH-dependent reductases (Feldstead and Bachur, 1980). While the physiological role of either enzyme remains unknown, it is generally assumed that aldose reductase reduces aldose sugars to their respective sugar alcohols while aldehyde reductase ...
T, Mizoguchi, H, Itabe, P F, Kador
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Physiological Relevance of Aldehyde Reductase and Aldose Reductase Gene Expression
1999Carbonyl compounds which are produced as intermediate metabolism during ordinary metabom or are present in food or drugs are known to be toxic to living organisms because of their high degree of reactivity. It has also been suggested that elevation in protein carbonyl groups is also a likely cause of aging (Stadtman, 1992).
J, Fujii +5 more
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