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Plant physiology and biochemistry : PPB, 2023
Aldehyde dehydrogenase (ALDH) superfamily, comprising enzymes dependent on NAD+ or NADP+, plays an important role in controlling plant growth and development, as well as in responsing to phytohormone and environmental stress.
Jing Xu +10 more
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Aldehyde dehydrogenase (ALDH) superfamily, comprising enzymes dependent on NAD+ or NADP+, plays an important role in controlling plant growth and development, as well as in responsing to phytohormone and environmental stress.
Jing Xu +10 more
semanticscholar +1 more source
, 2021
Aldehyde dehydrogenases (ALDHs) constitute an evolutionary conserved superfamily of oxidoreductases, which convert a large array of aldehydes to carboxylic acids.
Naim Stiti +2 more
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Aldehyde dehydrogenases (ALDHs) constitute an evolutionary conserved superfamily of oxidoreductases, which convert a large array of aldehydes to carboxylic acids.
Naim Stiti +2 more
semanticscholar +1 more source
Pharmacogenetics of aldehyde dehydrogenase (ALDH)
Pharmacology & Therapeutics, 1990Cette synthese aborde le metabolisme des aldehydes chez l'homme et les mammiferes, et en particulier le role de l'aldehyde deshydrogenase. Sont decrits les proprietes physicochimiques de l'enzyme, son expression genique, ses variants genetiques, son importance ...
H W, Goedde, D P, Agarwal
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Aldehyde dehydrogenase (ALDH) in Alzheimer’s and Parkinson’s disease
Journal of Neural Transmission, 2016Evidence suggests that aldehyde dehydrogenase (ALDH; E.C. 1.2.1.3) gene, protein expression and activity are substantially decreased in the substantia nigra of patients with Parkinson's disease (PD). This holds especially true for cytosolic ALDH1A1, while mitochondrial ALDH2 is increased in the putamen of PD.
E. Grünblatt, P. Riederer
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The Role of ALDH in the Metastatic Potential of Osteosarcoma Cells and Potential ALDH Targets
2020Aldehyde dehydrogenases are a family of enzymes that oxidize aldehydes to carboxylic acids. These enzymes are important in cellular homeostasis during oxidative stress by the elimination of toxic aldehyde by-products from various cellular processes. In osteosarcoma, aldehyde dehydrogenase 1A1has been described as a cancer stem cell marker. Its activity
Rebekah, Belayneh, Kurt, Weiss
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ALDH as a Stem Cell Marker in Solid Tumors
Current Stem Cell Research and Therapy, 2019:Aldehyde dehydrogenase (ALDH) is an enzyme that participates in important cellular mechanisms as aldehyde detoxification and retinoic acid synthesis; moreover, ALDH activity is involved in drug resistance, a characteristic of cancer stem cells (CSCs). Even though ALDH is found in stem cells, CSCs and progenitor cells, this enzyme has been successfully
Elizabeth Ortiz-Sánchez
exaly +3 more sources
ALDH as a Stem Cell marker in solid tumors.
Current Stem Cell Research & Therapy, 2018Aldehyde dehydrogenase [ALDH] is an enzyme that participates in important cellular mechanisms as aldehyde detoxification and retinoic acid synthesis; moreover, ALDH activity is involved in drug resistance, a characteristic of cancer stem cells [CSCs ...
Mariel E. Toledo-Guzmán +3 more
semanticscholar +1 more source
Pediatric Hematology and Oncology, 2013
The malignant cells of childhood acute lymphoblastic leukemia (ALL) do not form a homogenous entity but a collection of differently maturated blasts. The most immature leukemia cells may be more resistant to therapy than the bulk of more differentiated blasts. We studied 42 patients with childhood ALL treated according to the ALL-BFM 2000 protocol.
Jörg, Ahlers +5 more
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The malignant cells of childhood acute lymphoblastic leukemia (ALL) do not form a homogenous entity but a collection of differently maturated blasts. The most immature leukemia cells may be more resistant to therapy than the bulk of more differentiated blasts. We studied 42 patients with childhood ALL treated according to the ALL-BFM 2000 protocol.
Jörg, Ahlers +5 more
openaire +2 more sources
Biochemical Genetics, 1988
Isozyme phenotypes of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) from human gastroendoscopic as well as surgical gastric biopsies were determined by starch gel electrophoresis and agarose isoelectric focusing. gamma gamma ADH isozymes were expressed predominantly in the mucosal layer of the stomach, whereas beta beta isozymes were in
S J, Yin +7 more
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Isozyme phenotypes of alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) from human gastroendoscopic as well as surgical gastric biopsies were determined by starch gel electrophoresis and agarose isoelectric focusing. gamma gamma ADH isozymes were expressed predominantly in the mucosal layer of the stomach, whereas beta beta isozymes were in
S J, Yin +7 more
openaire +2 more sources
Materials Science and Engineering C: Materials for Biological Applications, 2019
The use of chemotherapy against brain tumors faces various limitations to achieving its therapeutic effect, due to both the inability of anticancer agents to cross the blood-brain barrier (BBB) and the formation of brain cancer stem cells (BCSCs ...
Yung-Chih Kuo, Li-Jung Wang, R. Rajesh
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The use of chemotherapy against brain tumors faces various limitations to achieving its therapeutic effect, due to both the inability of anticancer agents to cross the blood-brain barrier (BBB) and the formation of brain cancer stem cells (BCSCs ...
Yung-Chih Kuo, Li-Jung Wang, R. Rajesh
semanticscholar +1 more source