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Proliferating pancreatic beta-cells upregulate ALDH

Histochemistry and Cell Biology, 2014
High levels of aldehyde dehydrogenase (ALDH) activity have been regarded as a specific feature of progenitor cells and stem cells. Hence, as an indicator of ALDH activity, aldefluor fluorescence has been widely used for the identification and isolation of stem and progenitor cells.
Yinglan, Liu   +5 more
openaire   +2 more sources

ALDH marks leukemia stem cell

Blood, 2012
In this issue of Blood, Gerber et al use aldehyde dehydrogenase (ALDH) activity to further subdivide the CD34+CD38− compartment in the bone marrow of acute myeloid leukemia (AML) patients. They identify a unique population with intermediate ALDH activity (ALDHint) that contains leukemia stem cells (LSCs).
openaire   +2 more sources

The soybean aldehyde dehydrogenase (ALDH) protein superfamily

Gene, 2012
Aldehyde dehydrogenases (ALDHs) are members of NAD(P)(+)-dependent protein superfamily that catalyze the oxidation of a wide range of endogenous and exogenous highly reactive aliphatic and aromatic aldehyde molecules to their corresponding non toxic carboxylic acids. Research evidence has shown that ALDHs represent a promising class of genes to improve
Simeon O, Kotchoni   +4 more
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The role of ALDHs in lipid peroxidation-related diseases

International Journal of Biological Macromolecules
Lipid peroxidation presents the oxidative degradation of polyunsaturated fatty acids lincited by reactive species. Excessive accumulation of lipid peroxidation byproducts, including 4-hydroxy-2-nonenal (4-HNE) and malondialdehyde (MDA), causes protein dysfunction and various illnesses.
Ya-nan Wang, Shiyue Liu
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Brain ALDH as a possible modulator of voluntary ethanol intake

Alcohol, 1985
The relationship between voluntary ethanol intake and brain aldehyde dehydrogenase (ALDH) activity was investigated in the laboratory rat. Voluntary ethanol intake was compared to subcellular forms of brain ALDH. Mitochondrial, microsomal and cytosolic fractions were prepared and recovered ALDH activity of each form was compared to voluntary ethanol ...
S M, Socaransky, C M, Aragon, Z, Amit
openaire   +2 more sources

Members of the ALDH Gene Family are Lens and Corneal Crystallins

1993
Many of the major lens proteins, known as crystallins, responsible for the structural integrity and functional utility of this visual tissue have been previously shown to be recruited proteins. This phenomena of a protein that is expressed and functions elsewhere acquiring a new function in another tissue has been termed 'gene sharing'.
D L, Cooper   +3 more
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Genetski polimorfizam ADH i ALDH

2001
Rezultati novijih istraživanja potvrđuju da je predispozicija za alkoholnu ovisnost i/ili razvoj alkoholizma barem djelomično genetski uvjetovana, a alkoholizam se opisuje kao moždani neuro-psiho-farmakogenetski poremećaj. Nadalje, poznato je da većina enzima uključena u metabolizam alkohola pokazuju genetske polimorfizme koji su etnički različito ...
Topić, Elizabeta, Štefanović, Mario
openaire  

ALDH

2010
Jean-Michel Scherrmann   +199 more
openaire   +1 more source

Tumor associated ALDH in the liver

Journal of Hepatology, 1990
A. Shibuya, H. Shibata, A. Takeuch
openaire   +1 more source

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