Results 181 to 190 of about 23,764 (226)
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Proliferating pancreatic beta-cells upregulate ALDH
Histochemistry and Cell Biology, 2014High levels of aldehyde dehydrogenase (ALDH) activity have been regarded as a specific feature of progenitor cells and stem cells. Hence, as an indicator of ALDH activity, aldefluor fluorescence has been widely used for the identification and isolation of stem and progenitor cells.
Yinglan, Liu +5 more
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Blood, 2012
In this issue of Blood, Gerber et al use aldehyde dehydrogenase (ALDH) activity to further subdivide the CD34+CD38− compartment in the bone marrow of acute myeloid leukemia (AML) patients. They identify a unique population with intermediate ALDH activity (ALDHint) that contains leukemia stem cells (LSCs).
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In this issue of Blood, Gerber et al use aldehyde dehydrogenase (ALDH) activity to further subdivide the CD34+CD38− compartment in the bone marrow of acute myeloid leukemia (AML) patients. They identify a unique population with intermediate ALDH activity (ALDHint) that contains leukemia stem cells (LSCs).
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The soybean aldehyde dehydrogenase (ALDH) protein superfamily
Gene, 2012Aldehyde dehydrogenases (ALDHs) are members of NAD(P)(+)-dependent protein superfamily that catalyze the oxidation of a wide range of endogenous and exogenous highly reactive aliphatic and aromatic aldehyde molecules to their corresponding non toxic carboxylic acids. Research evidence has shown that ALDHs represent a promising class of genes to improve
Simeon O, Kotchoni +4 more
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The role of ALDHs in lipid peroxidation-related diseases
International Journal of Biological MacromoleculesLipid peroxidation presents the oxidative degradation of polyunsaturated fatty acids lincited by reactive species. Excessive accumulation of lipid peroxidation byproducts, including 4-hydroxy-2-nonenal (4-HNE) and malondialdehyde (MDA), causes protein dysfunction and various illnesses.
Ya-nan Wang, Shiyue Liu
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Brain ALDH as a possible modulator of voluntary ethanol intake
Alcohol, 1985The relationship between voluntary ethanol intake and brain aldehyde dehydrogenase (ALDH) activity was investigated in the laboratory rat. Voluntary ethanol intake was compared to subcellular forms of brain ALDH. Mitochondrial, microsomal and cytosolic fractions were prepared and recovered ALDH activity of each form was compared to voluntary ethanol ...
S M, Socaransky, C M, Aragon, Z, Amit
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Members of the ALDH Gene Family are Lens and Corneal Crystallins
1993Many of the major lens proteins, known as crystallins, responsible for the structural integrity and functional utility of this visual tissue have been previously shown to be recruited proteins. This phenomena of a protein that is expressed and functions elsewhere acquiring a new function in another tissue has been termed 'gene sharing'.
D L, Cooper +3 more
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Genetski polimorfizam ADH i ALDH
2001Rezultati novijih istraživanja potvrđuju da je predispozicija za alkoholnu ovisnost i/ili razvoj alkoholizma barem djelomično genetski uvjetovana, a alkoholizam se opisuje kao moždani neuro-psiho-farmakogenetski poremećaj. Nadalje, poznato je da većina enzima uključena u metabolizam alkohola pokazuju genetske polimorfizme koji su etnički različito ...
Topić, Elizabeta, Štefanović, Mario
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Tumor associated ALDH in the liver
Journal of Hepatology, 1990A. Shibuya, H. Shibata, A. Takeuch
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