The Utility of a Small Animal Grip Strength Measurement Device as a Model for Studying Exercise-Induced Muscle Damage [PDF]
AntioxidantsExercise-induced muscle damage (EIMD) is characterized by structural muscle tissue damage and elevated biochemical markers following high-intensity or unaccustomed exercise.
Haruki Kobori +9 more
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An atypical presentation of immune checkpoint inhibitor associated myositis with normal creatine kinase: a case report [PDF]
Frontiers in ImmunologyImmune checkpoint inhibitors (ICIs) have been revolutionary in the field of cancer therapeutics. Myositis is a known rheumatic immunotherapy related adverse event with a fatality rate of 26.8% when associated with myasthenia gravis and 51.3% when ...
Monika A. Satoskar +6 more
doaj +2 more sources
Investigating the Role of Myopathy Markers Ex-pression (Creatine Kinase, Aldolase, INF-γ and TNF-α) Following the Use of Chemotherapy Drugs in Children with Leukemia [PDF]
Iranian South Medical JournalBackground: Acute lymphoblastic leukemia (ALL) is one of the most common childhood malignancies with a prevalence of 40 per million children under 15 years old.
Samireh Ghafouri +5 more
doaj +3 more sources
Molecular and evolutionary determinants for protein interaction within a class II aldolase/Adducin domain. [PDF]
PLoS ONEThe appearance of modular protein interaction domains represents a crucial step in the evolution of multicellularity. For example, the class II aldolase domain (ALDODOM) found within the Adducin gene family shares sequence and structural homology to a ...
Marina E Seheon +2 more
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Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Male Mice Consuming Alcohol Attenuates Glycolysis [PDF]
Nature CommunicationsmTORC1 promotes protein translation, learning and memory, and neuroadaptations that underlie alcohol use disorder (AUD). The mechanisms underlying alcohol-mediated mTORC1-dependent neuroadaptations that drive AUD are not well understood.
Yann Ehinger +9 more
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Highly Efficient Synthesis of Rare Sugars from Glycerol in Endotoxin-Free ClearColi by Fermentation
Foods, 2023 Rare sugars possess potential applications as low-calorie sweeteners, especially for anti-obesity and anti-diabetes. In this study, a fermentation biosystem based on the “DHAP-dependent aldolases strategy” was established for D-allulose and D-sorbose ...
Yahui Gao +3 more
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mBio, 2023 The preferred carbon source of Staphylococcus aureus and many other pathogens is glucose, and its consumption is critical during infection. However, glucose utilization increases the cellular demand for manganese, a nutrient sequestered by the host as a ...
Paola K. Párraga Solórzano +3 more
doaj +1 more source
Animals, 2023 Equine gastric ulcer syndrome (EGUS) is a highly prevalent disease that affects horses worldwide. Within EGUS, two different forms have been described: equine squamous gastric disease (ESGD) and equine glandular gastric disease (EGGD).
Alberto Muñoz-Prieto +8 more
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Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure. [PDF]
PLoS ONE, 2013 One of the most adaptive facultative anaerobes among vertebrates is the freshwater turtle, Trachemys scripta elegans. Upon a decrease in oxygen supply and oxidative phosphorylation, these turtles are able to reduce their metabolic rate and recruit ...
Neal J Dawson +2 more
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High-resolution cryo-EM using beam-image shift at 200 keV
IUCrJ, 2020 Recent advances in single-particle cryo-electron microscopy (cryo-EM) data collection utilize beam-image shift to improve throughput. Despite implementation on 300 keV cryo-EM instruments, it remains unknown how well beam-image-shift data collection ...
Jennifer N. Cash +3 more
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