Results 101 to 110 of about 33,271 (218)

Expression of USP25 associates with fibrosis, inflammation and metabolism changes in IgG4-related disease

Nature Communications
IgG4-related disease (IgG4-RD) has complex clinical manifestations ranging from fibrosis and inflammation to deregulated metabolism. The molecular mechanisms underpinning these phenotypes are unclear.
Panpan Jiang, Yukai Jing, Siyu Zhao, Caini Lan, Lu Yang, Xin Dai, Li Luo, Shaozhe Cai, Yingzi Zhu, Heather Miller, Juan Lai, Xin Zhang, Xiaochao Zhao, Yonggui Wu, Jingzhi Yang, Wen Zhang, Fei Guan, Bo Zhong, Hisanori Umehara, Jiahui Lei, Lingli Dong, Chaohong Liu   +21 more
doaj   +1 more source

Uncovering the Key Factors Influencing Phytochemical and Phytopharmacological Properties During Medicinal Plant Processing

eFood, Volume 7, Issue 1, February 2026.
From farm to pharma, this review details the engineering of quality in medicinal plants through a science‐driven approach: it first elucidates how genetic and environmental factors inscribe the plant's phytochemical and phytopharmacological profile before harvest, and then dissects the postharvest techniques and technologies—chemical and thermal pre ...
Elyas Aryakia
wiley   +1 more source

Maternal Fructose Intake During Pregnancy Induced the Hepatic Glucose Homeostasis Imbalance in the Offspring by Inhibiting Glucokinase

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Schematic diagram of the core mechanisms. The study demonstrated that maternal fructose intake during pregnancy led to glucose intolerance and insulin resistance in offspring. The abnormal hepatic glucose metabolism in offspring was associated with decreased GK expression, which was inhibited by DNMT3B.
Yahui Miao, Ziyu Meng, Shihang Chen, Xiaoyu Li, Ting Fang, Xiaoqing Deng, Bei Sun, Liming Chen   +7 more
wiley   +1 more source

The Impact of Lighting Treatments on the Biosynthesis of Phenolic Acids in Black Wheat Seedlings

Foods
Light, as a crucial environmental determinant, profoundly influences the synthesis of secondary metabolites in plant metabolism. This study investigated the impacts of the red light combined with ultraviolet-A (UV-A) and ultraviolet-B (UV-B) treatments ...
Hongjie Lan, Chunping Wang, Zhengfei Yang, Jiangyu Zhu, Weiming Fang, Yongqi Yin   +5 more
doaj   +1 more source

Ko‐Assemblierungen regulieren die katalytische Aktivität von Peptidfibrillen

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Katalytische selbstassemblierende Peptide (kSAPs) bilden Fibrillen, die die Retro‐Aldol‐Reaktion von Methodol katalysieren. Die Ko‐Assemblierung mit inaktiven Peptiden reguliert die katalytische Aktivität, indem sie die Zugänglichkeit des Substrats und den Abstand zum nukleophilen Lysin verändert.
Albin Lahu, Shao‐Lin Wu, Maximilian Schuler, Francesca Mazzotta, Ardit Ramadani, Emirhan Koca, Ingo Lieberwirth, Katharina Landfester, Torsten John, David Y. W. Ng, Tanja Weil   +10 more
wiley   +1 more source

Co‐Assemblies Regulate the Catalytic Activity of Peptide Fibrils

Angewandte Chemie International Edition, Volume 65, Issue 2, 9 January 2026.
Catalytic self‐assembling peptides (cSAPs) form fibrils that catalyze the retro‐aldol reaction of Methodol. Co‐assembly with inactive peptides tunes catalytic efficiency by altering substrate accessibility and the distance to the nucleophilic lysine.
Albin Lahu, Shao‐Lin Wu, Maximilian Schuler, Francesca Mazzotta, Ardit Ramadani, Emirhan Koca, Ingo Lieberwirth, Katharina Landfester, Torsten John, David Y. W. Ng, Tanja Weil   +10 more
wiley   +1 more source

Aldolase B [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +2 more sources

Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance [PDF]

, 2002
Gabriella Esposito, Luigi Vitagliano, Rita Santamaria, Antonietta Viola, Adriana Zagari, Francesco Salvatore   +5 more
openalex   +1 more source

Functional domains involved in the interaction between Orc1 and transcriptional repressor AlF-C that bind to an origin/promoter of the rat aldolase B gene [PDF]

, 2002
Yasushi Saitoh
openalex   +1 more source

Multiomics approach provides insight into altered choline metabolism and liver injury in patients with glycogen storage disease type Ia

Scientific Reports
Glycogen storage disease type Ia (GSDIa) is an inherited disorder of carbohydrate metabolism. Patients present with excessive storage of glycogen and fat in the liver and kidneys and are potentially at risk of developing long-term complications ...
Francesca Pirozzi, Ramin Amiri, Camilla Luni, Alessandro Rossi, Daniela Melis, Roberta Fedele, Carmen Rosano, Pietro Strisciuglio, Maaike H. Oosterveer, Terry G. J. Derks, Giancarlo Parenti, Marianna Caterino, Margherita Ruoppolo   +12 more
doaj   +1 more source