Results 1 to 10 of about 12,022 (131)

Epitope-Based Peptide Vaccine Design against Fructose Bisphosphate Aldolase of Candida glabrata: An Immunoinformatics Approach [PDF]

Journal of Immunology Research, 2021
Background. Candida glabrata is a human opportunistic pathogen that can cause life-threatening systemic infections. Although there are multiple effective vaccines against fungal infections and some of these vaccines are engaged in different stages of ...
Lina Mohamed Elamin Elhasan, Mohamed B. Hassan, Reham M. Elhassan, Fatima A. Abdelrhman, Essam A. Salih, Asma Ibrahim H, Amna A. Mohamed, Hozaifa S. Osman, Marwa Saad M. Khalil, Athar A. Alsafi, Abeer Babiker Idris, Mohamed A. Hassan   +11 more
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Epitope-Based Peptide Vaccine Against Fructose-Bisphosphate Aldolase of Using Immunoinformatics Approaches [PDF]

Bioinformatics and Biology Insights, 2018
Background: Mycetoma is a distinct body tissue destructive and neglected tropical disease. It is endemic in many tropical and subtropical countries.
Arwa A Mohammed, Ayman MH ALnaby, Solima M Sabeel, Fagr M AbdElmarouf, Amina I Dirar, Mostafa M Ali, Mustafa A Khandgawi, Abdelhameed M Yousif, Eman M Abdulgadir, Magdi A Sabahalkhair, Ayman E Abbas, Mohammed A Hassan   +11 more
doaj   +2 more sources

The fructose-bisphosphate, Aldolase A (ALDOA), facilitates DNA-PKcs and ATM kinase activity to regulate DNA double-strand break repair [PDF]

Scientific Reports, 2023
Glucose metabolism and DNA repair are fundamental cellular processes frequently dysregulated in cancer. In this study, we define a direct role for the glycolytic Aldolase A (ALDOA) protein in DNA double-strand break (DSB) repair.
Thais Sobanski, Amila Suraweera, Joshua T. Burgess, Iain Richard, Chee Man Cheong, Keyur Dave, Maddison Rose, Mark N. Adams, Kenneth J. O’Byrne, Derek J. Richard, Emma Bolderson   +10 more
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Fructose-Bisphosphate Aldolase Mediating Pollen-Food Allergy Syndrome [PDF]

Journal of Asthma and Allergy
Lisha Li,* Junda Li,* Kai Guan Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical
Li L, Li J, Guan K
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Design of Epitope-Based Peptide Vaccine against Pseudomonas aeruginosa Fructose Bisphosphate Aldolase Protein Using Immunoinformatics [PDF]

Journal of Immunology Research, 2020
Pseudomonas aeruginosa is a common pathogen that is responsible for serious hospital-acquired infections, ventilator-associated pneumonia, and various sepsis syndromes.
Mustafa Elhag, Ruaa Mohamed Alaagib, Nagla Mohamed Ahmed, Mustafa Abubaker, Esraa Musa Haroun, Sahar Obi Abd Albagi, Mohammed A. Hassan   +6 more
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A Dual-localized Fructose Bisphosphate Aldolase is Essential for Chloroplast Development and Carbon Metabolism in Rice [PDF]

Rice
Fructose-1,6-bisphosphate aldolase (FBA) stands as a pivotal enzyme involved within the Calvin cycle and glycolytic pathways in bacteria and higher plants, but the specific function of OsFBA in rice is still unclear. Here, we identified a chloroplast and
Xin Liu, Yingbo Gao, Siyuan Tang, Linli Ben, Xiaoxiang Zhang, Guichun Dong, Juan Zhou, Lingshang Lin, Zefeng Yang, Yong Zhou, Jianye Huang, Youli Yao   +11 more
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Proteomics Used in Identifying Novel Correlates of Disease in Pediatric Metabolic Dysfunction‐Associated Steatotic Liver Disease [PDF]

Clinical and Translational Science
Metabolic dysfunction‐associated liver disease (MASLD) is a leading cause of liver disease in children. There is a paucity of data on potential biomarkers and therapeutic targets, especially in pediatric MASLD.
Diego Paine‐Cabrera, Lisa K. Harvey, Michele T. Pritchard, John Thyfault, Antonio Artigues, Udayan Apte, Voytek Slowik   +6 more
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Proteomic antibacterial characterization of flavonoid xanthohumol and probiotic Clostridium butyricum on pathogenic Clostridioides difficile [PDF]

Chinese Medicine
Background The management of dysbiotic gut microbiota in Clostridioides difficile infection has attracted increasing scholarly attention. The development of therapeutic agents with low toxicity, derived from both the flavonoid xanthohumol and the short ...
Shenkun Wei, Guorong Li, Qiong Yang, Xinping Zhu, Junjie Liang, Mengyi Liu, Zijian Chen, Xia Liu, Jun-Yu Xu, Wei Chen   +9 more
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Structures, characteristics and functions of fructose-1,6-bisphosphate aldolase in various tissues

Acta Societatis Botanicorum Poloniae, 2023
Aldolase exhibits multiple functions in a variety of organisms, including fungi, unicellular algae and plants, and so on. Furthermore, different isoforms of fructose 1,6-bisphosphate aldolase (FBA) exhibit significantly different characteristics and ...
Lina Yang, Yike Liu, Zhanjun Xue, Qingyun Li, Bingbing Cai   +4 more
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Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure. [PDF]

PLoS ONE, 2013
One of the most adaptive facultative anaerobes among vertebrates is the freshwater turtle, Trachemys scripta elegans. Upon a decrease in oxygen supply and oxidative phosphorylation, these turtles are able to reduce their metabolic rate and recruit ...
Neal J Dawson, Kyle K Biggar, Kenneth B Storey   +2 more
doaj   +1 more source