Results 11 to 20 of about 12,022 (131)

Multifunctional Fructose 1,6-Bisphosphate Aldolase as a Therapeutic Target

open access: yesFrontiers in Molecular Biosciences, 2021
Fructose 1,6-bisphosphate aldolase is a ubiquitous cytosolic enzyme that catalyzes the fourth step of glycolysis. Aldolases are classified into three groups: Class-I, Class-IA, and Class-II; all classes share similar structural features but low amino ...
David B. Pirovich   +2 more
doaj   +1 more source

Aldolase A deficiency: Report of new cases and literature review

open access: yesMolecular Genetics and Metabolism Reports, 2021
Aldolase A (ALDOA), is the predominant isoform of aldolase in skeletal muscle and erythrocytes that catalyzes the reversibleconversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate.
C. Papadopoulos   +6 more
doaj   +1 more source

Alteration of de novo glucose production contributes to fasting hypoglycaemia in Fyn deficient mice. [PDF]

open access: yesPLoS ONE, 2013
Previous studies have demonstrated that glucose disposal is increased in the Fyn knockout (FynKO) mice due to increased insulin sensitivity. FynKO mice also display fasting hypoglycaemia despite decreased insulin levels, which suggested that hepatic ...
Yingjuan Yang   +7 more
doaj   +1 more source

Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration. [PDF]

open access: yesPLoS ONE, 2014
Fructose-bisphosphate aldolase A (ALDOA) is a key enzyme in glycolysis and is responsible for catalyzing the reversible conversion of fructose-1,6-bisphosphate to glyceraldehydes-3-phosphate and dihydroxyacetone phosphate.
Sha Du   +9 more
doaj   +1 more source

Interrogating the Role of the Two Distinct Fructose-Bisphosphate Aldolases of Bacillus methanolicus by Site-Directed Mutagenesis of Key Amino Acids and Gene Repression by CRISPR Interference

open access: yesFrontiers in Microbiology, 2021
The Gram-positive Bacillus methanolicus shows plasmid-dependent methylotrophy. This facultative ribulose monophosphate (RuMP) cycle methylotroph possesses two fructose bisphosphate aldolases (FBA) with distinct kinetic properties.
Kerstin Schultenkämper   +7 more
doaj   +1 more source

Molecular characterization and immune efficacy of fructose-1,6-bisphosphate aldolase from Haemaphysalis longicornis (Acari: Ixodidae)

open access: yesParasites & Vectors, 2023
Background Ticks are obligate hematophagous ectoparasites that transmit a variety of pathogens to humans, wildlife and domestic animals. Vaccination is an effective and environmentally friendly method for tick control. Fructose-1,6-bisphosphate aldolase (
Yuan-Yuan Cao   +6 more
doaj   +1 more source

Fructose biphosphate aldolase: A new cassava allergen

open access: yesWorld Allergy Organization Journal, 2023
Background: Food allergy has considerably increased in recent years and this situation has been aggravated mainly by the consumption of more processed and complex foods, since minor or potentially allergenic foods are not required to be labeled.
Anne K.R.M. Ventura, Ph.D   +10 more
doaj   +1 more source

Characterization of Fructose-1,6-Bisphosphate Aldolase 1 of Echinococcus multilocularis

open access: yesVeterinary Sciences, 2021
Glycolysis is one of the important ways by which Echinococcus multilocularis acquires energy. Fructose-1, 6-bisphosphate aldolase (FBA) plays an important role in this process, but it is not fully characterized in E. multilocularis yet.
Xuedong He   +10 more
doaj   +1 more source

Exogenous Si Mitigates the Effects of Cinnamic-Acid-Induced Stress by Regulating Carbon Metabolism and Photosynthetic Pigments in Cucumber Seedlings

open access: yesAgronomy, 2022
(1) Background: Cinnamic acid (CA) is a harmful substance secreted by the roots of continuous-cropping crops. (2) Methods: This study aimed to investigate how exogenous Si affects chlorophyll content and carbon metabolism in cucumber seedlings under CA ...
Jian Lyu   +9 more
doaj   +1 more source

Exogenous spermidine enhances expression of Calvin cycle genes andphotosynthetic efficiency in sweet sorghum seedlings under salt stress

open access: yesBiologia Plantarum, 2019
Salinity adversely affects plants resulting in disruption to plant growth and physiology. Previously, it has been shown that these negative effects can be alleviated by various exogenous polyamines.
A.I. EL SAYED   +3 more
doaj   +1 more source

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