Results 181 to 190 of about 33,271 (218)
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Crystallographic B-Factors Highlight Energetic Frustration in Aldolase Folding
The Journal of Physical Chemistry B, 2008Kinetic simulations of the folding and unfolding of the mammalian TIM barrel protein aldolase were conducted to determine if a minimalist monomeric Gō model, using the native structure to determine attractive energies in the protein chain, could capture the experimentally determined folding pathway.
Rao, Maithreyi K. +2 more
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Cloning and characterisation of a fish aldolase B gene
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1995A full length cDNA clone representing an aldolase mRNA was isolated from a sea bream (Sparus aurata) liver cDNA library. Sequencing of this clone revealed it to encode a 364 amino acid protein with 74% amino acid identity to human aldolase B and slightly lower similarity to human aldolase A and C.
Llewellyn, Lynda +5 more
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Structure and genomic organization of the rat aldolase B gene
Journal of Molecular Biology, 1985The structure of the chromosomal gene encoding rat aldolase isozyme B has been elucidated by sequence analysis of cloned genomic DNA. This gene comprises about 14 X 10(3) base-pairs of DNA, and is separated into nine exons by eight intervening sequences.
K, Tsutsumi +6 more
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Biosynthesis of Aldolase B by Free Ribosomes in Rat Liver
The Journal of Biochemistry, 1980Free ribosomes and membrane-bound ribosomes were prepared from rat livers, and the contributions of these two types of ribosomes to the synthesis of aldolase B were studied by the immunoprecipitation of [3H]puromycin-labeled nascent peptides with a rabbit antibody to this enzyme.
T, Oda, T, Omura
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Case Report: Heterogeneity of Aldolase B in Hereditary Fructose Intolerance
The American Journal of the Medical Sciences, 1991Hereditary fructose intolerance (HFI) is a recessive genetic disorder with an estimated disease frequency of 1 in 20,000 and a carrier frequency of 1 in 70. Affected individuals are unable to assimilate fructose from fruit sugars and may develop severe hypoglycemia, metabolic problems, and death if misdiagnosed.
U B, Kaiser, R A, Hegele
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Decreased serum aldolase B levels in patients with malignant tumors
Cancer, 1988Serum aldolase B levels were determined in patients with malignant tumors using a radioimmunoassay method. Thirty-one of 52 patients with malignant tumors had decreased serum aldolase B levels of less than 20 ng/ml, whereas almost all of the normal subjects and the patients with liver diseases and other benign diseases showed serum aldolase B levels of
M, Asaka +4 more
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Human aldolase B serum levels: A marker of liver injury
Hepatology, 1984A solid-phase, noncompetitive radioimmunoassay has been developed for aldolase B in human serum and tissues. Aldolase B was purified from human liver, and specific antisera to purified aldolase B were obtained from chickens. Specific antihuman aldolase B IgG was purified by affinity chromatography.
M, Asaka +3 more
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Molecular analysis of aldolase B genes in hereditary fructose intolerance
The Lancet, 1990The molecular basis of hereditary fructose intolerance (HFI) was studied in 50 subjects (41 pedigrees, 82 apparently independent mutant alleles of aldolase B) by direct analysis of aldolase B genes amplified by means of the polymerase chain reaction. The mutation A149P (ala 149----pro) was found in 67% of alleles but was significantly more common in ...
Cross N. C. P. +14 more
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Human aldolase B subunit-specific radioimmunoassay.
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1983A radioimmunoassay was developed for the direct quantification of aldolase B in human serum and tissues. The method is a double antibody radioimmunoassay technique using radioiodinated aldolase B homopolymer as ligand, chicken antibodies to aldolase B and rabbit antibodies to chicken IgG.
M, Asaka, E, Alpert
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Nucleotide sequence of a cDNA clone for human aldolase B
Biochemical and Biophysical Research Communications, 1983Two specific clones for human aldolase B were isolated from a human liver cDNA library using a rat aldolase B cDNA probe. The clones were identified by positive hybridization-selection and one of them was sequenced. The 127 C-terminal residues of the human protein were deduced from this nucleotide sequence analysis.
Besmond, Claude +6 more
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