Results 91 to 100 of about 96,578 (258)

Aldosterone in Gynecology and Its Involvement on the Risk of Hypertension in Pregnancy

open access: yesFrontiers in Endocrinology, 2019
Aldosterone is the main mineralocorticoid hormone, responsible of the regulation of fluid and electrolyte balance and blood pressure. It acts also as a pro-inflammatory factor responsible of an increased cardiovascular risk, independent from blood ...
Chiara Sabbadin   +8 more
doaj   +1 more source

Health‐related quality of life across heart failure categories: associations with clinical characteristics and outcomes

open access: yesESC Heart Failure, EarlyView.
Abstract Aims The study aims to examine characteristics and outcomes associated with health‐related quality of life (HRQoL) in patients with heart failure (HF) with preserved, mildly reduced and reduced ejection fraction (EF) (HFpEF, HFmrEF and HFrEF). Methods and results Data on HRQoL were collected in the Swedish Heart Failure Registry (SwedeHF; 2000–
Camilla Settergren   +6 more
wiley   +1 more source

Does Mineralocorticoid Receptor Antagonism Prevent Calcineurin Inhibitor-Induced Nephrotoxicity?

open access: yesFrontiers in Medicine, 2017
Calcineurin inhibitors have markedly reduced acute rejection rates in renal transplantation, thus significantly improved short-term outcome. The beneficial effects are, however, tampered by acute and chronic nephrotoxicity leading to interstitial ...
Line Aas Mortensen   +5 more
doaj   +1 more source

Risk classification for long‐term mortality among patients with acute heart failure: China PEACE 4YMortality

open access: yesESC Heart Failure, EarlyView.
Abstract Aims There are limited tools to predict long‐term mortality among patients hospitalized with acute heart failure (AHF) in China. This study aimed to develop and validate a model to predict long‐term mortality risk among patients who were hospitalized with AHF and discharged alive.
Wei Wang   +8 more
wiley   +1 more source

Frailty determinants in heart failure: Inflammatory markers, cognitive impairment and psychosocial interaction

open access: yesESC Heart Failure, EarlyView.
Abstract Aims This study aimed to identify factors associated with frailty in heart failure (HF) patients, focusing on demographic, biochemical and health‐related variables. It also explored the correlation between frailty and comorbidities such as malnutrition, cognitive impairment and depression, assessing how these factors interact to influence ...
Marta Wleklik   +6 more
wiley   +1 more source

Aldosterone receptor antagonists: current perspectives and therapies

open access: yesVascular Health and Risk Management, 2013
Jason L Guichard, Donald Clark III, David A Calhoun, Mustafa I Ahmed University of Alabama at Birmingham, Department of Medicine, Division of Cardiovascular Disease, Vascular Biology and Hypertension Program, Birmingham, AL, USA Abstract: Aldosterone is ...
Guichard JL   +3 more
doaj  

The efficacy and safety of sodium‐glucose cotransporter 2 inhibitors in patients aged over 80 years with heart failure

open access: yesESC Heart Failure, EarlyView.
Abstract Aims Sodium‐glucose cotransporter 2 (SGLT2) inhibitors (SGLT2i) have demonstrated effectiveness in reducing cardiovascular death and heart failure hospitalization (HFH). However, the efficacy and safety of SGLT2 inhibitors in elderly patients with poor general status, such as very low bodyweight or low nutritional status, who are not included ...
Kenji Nakano   +15 more
wiley   +1 more source

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