Results 91 to 100 of about 232,884 (341)
British Journal of Clinical Pharmacology, EarlyView.Aims This study investigated factors associated with and outcomes of combined loop diuretics with hydrochlorothiazide (HCTZ) for acute decompensated heart failure (ADHF). Methods In this retrospective study, adults hospitalized for ADHF and who received intravenous loop diuretics between January 2016 and March 2023 were enrolled.
Chia‐Chen Hsu +6 more
wiley +1 more source
Resistant/Refractory Hypertension and Sleep Apnoea: Current Knowledge and Future Challenges [PDF]
, 2019 Hypertension is one of the most frequent cardiovascular risk factors. The population of hypertensive patients includes some phenotypes whose blood pressure levels are particularly difficult to control, thus putting them at greater cardiovascular risk ...
Barbé Illa, Ferran +7 more
core +2 more sources
Redox Biology, 2017 Aldosterone, with pro-oxidation and pro-autophagy capabilities, plays a key role in liver fibrosis. However, the mechanisms underlying aldosterone-promoted liver sinusoidal endothelial cells (LSECs) defenestration remain unknown.
Xiaoying Luo +12 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aims “Triple whammy” (TW) refers to the concomitant use of diuretics, renin‐angiotensin‐aldosterone system inhibitors (RAASI) and non‐steroidal anti‐inflammatory drugs (NSAIDs). The aim of this article is to analyse the association between TW exposure and acute kidney injury (AKI), among other morbi‐mortality outcomes.
Dulce María Calvo +4 more
wiley +1 more source
The prevalence of resistant arterial hypertension and secondary causes in a cohort of hypertensive patients: a single center experience [PDF]
, 2017 The prevalence of resistant hypertension (RHT) still remains unknown. Aim of the study was to investigate in a large cohort of hypertensive patients the prevalence of RHT, and to identify in these patients the secondary forms of arterial hypertension (SH)
Concistre, Antonio +13 more
core +2 more sources
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source
Pharmacological effects of raas blockade in ischemic nephropathy [PDF]
, 2016 Background: The management of ischemic nephropathy due to atherosclerotic renal artery stenosis has become increasingly conservative in the modern era, with current guidelines recommending optimized medical therapy as the initial step.
Barbano, Biagio +8 more
core +1 more source
Role of the Renin-Angiotensin System and Aldosterone on Cardiometabolic Syndrome
International Journal of Hypertension, 2011 Aldosterone facilitates cardiovascular damage by increasing blood pressure and through different mechanisms that are independent of its effects on blood pressure.
P. Stiefel +3 more
doaj +1 more source
Asian Journal of Andrology, 2018 Emerging evidence indicates that aldosterone and mineralocorticoid receptors (MRs) are associated with the pathogenesis of erectile dysfunction. However, the molecular mechanisms remain largely unknown.
Fei Wu +6 more
doaj +1 more source
Journal of Veterinary Internal Medicine, 2021 Background Desoxycorticosterone pivalate (DOCP) is a commonly used mineralocorticoid replacement for dogs with primary hypoadrenocorticism (HA), but manufacturer‐recommended dosing protocols can be cost‐prohibitive.
Alysha M. Vincent +6 more
doaj +1 more source