Results 71 to 80 of about 119,651 (301)

Both aldosterone and spironolactone can modulate the intracellular ACE/ANG II/AT1 and ACE2/ANG (1‐7)/MAS receptor axes in human mesangial cells

open access: yesPhysiological Reports, 2019
The kidney is an important target of the renin‐ANG‐aldosterone system (RAAS). To date, several studies have demonstrated the existence of a local RAAS in various tissues, including the renal tissue.
Danielle Stoll   +3 more
doaj   +1 more source

Interventional Mitral Valve Edge‐to‐Edge Repair in Patients Above 85 Years of Age

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Mitral valve transcatheter‐edge‐to‐edge repair (M‐TEER) is routinely performed in patients with severe mitral regurgitation (MR) at high operative risk, frequently including elderly patients. Patients ≥ 85 years, however, are frequently excluded in clinical studies.
Florian Jürgens   +8 more
wiley   +1 more source

Higher blood aldosterone level in metabolic syndrome is independently related to adiposity and fasting plasma glucose

open access: yes, 2017
Background: Hypoadiponectinemia is a well-known state associated with metabolic syndrome (MetS) and insulin resistance (IR). Recently aldosterone has been highly associated with high blood pressure, and may thus be a possible biomarker for MetS and IR ...
曾芬郁;楊偉勛;黃國晉;陳祈玲   +1 more
core   +1 more source

Relationship between blood pressure level and activity of renin-aldosterone axis in patients with essential hypertension—a retrospective study [PDF]

open access: yesPeerJ
Background A study indicates that elevated aldosterone levels increase the risk of hypertension by 16%. This retrospective cohort study examines the relationship between blood pressure and renin-aldosterone levels in patients with essential hypertension (
Peijuan Li   +5 more
doaj   +2 more sources

Temporal Trends and Prognosis in Rotational Atherectomy: A Comparison of Contemporary and Traditional Eras

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Rotational atherectomy (RA) has undergone considerable technical modernization in recent years. This study evaluated whether RA performed in the contemporary era was associated with superior cardiovascular outcomes compared with the traditional era. Aims To compare the clinical characteristics and cardiovascular outcomes of patients
Ravi Vazirani   +15 more
wiley   +1 more source

Aldosterone Induces Tissue Inhibitor of Metalloproteinases-1 Expression and Further Contributes to Collagen Accumulation From Clinical to Bench Studies

open access: yes, 2017
Aldosterone induces myocardial fibrosis. Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a key factor of myocardial fibrosis. This study tested the hypothesis that aldosterone induces TIMP-1 expression and contributes to the fibrotic process.
Hung, Chi-Sheng;Chou, Chia-Hung;Liao, Che-Wei;Lin, Yen-Tin;Wu, Xue-Ming;Chang, Yi-Yao;Chen, Ying-Hsien;Wu, Vin-Cent;Su, Ming-Jai;Ho, Yi-Lwun;Chen, Ming-Fong;Wu, Kwan-Dun;Lin, Yen-Hung   +1 more
core   +1 more source

Changes of aldosterone levels in patients with type 2 diabetes complicated by moderate to severe obstructive sleep apnea–hypopnea syndrome before and after treatment with continuous positive airway pressure

open access: yesJournal of International Medical Research, 2019
Objective Both obstructive sleep apnea–hypopnea syndrome (OSAHS) and type 2 diabetes mellitus (T2DM) are closely related to the renin-angiotensin-aldosterone system.
Jie Zhang, Lin Tian, Lixin Guo
doaj   +1 more source

Baseline Body Mass Index Category and Incident Treated Hypertension in Australian Men: A Linked Prospective Cohort Study Using PBS/MBS Data

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Kaplan–Meier hypertension‐free survival by baseline body mass index category, primary adult cohort (men aged ≥ 18 years, n = 12,742). Time since baseline in years is plotted on the horizontal axis and the probability of remaining free of treated hypertension is plotted on the vertical axis. Numbers at risk are shown beneath the plot.
Ebenezer Afrifa‐Yamoah
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang   +7 more
wiley   +1 more source

Aldosterone induces inflammatory cytokines in penile corpus cavernosum by activating the NF-κB pathway

open access: yesAsian Journal of Andrology, 2018
Emerging evidence indicates that aldosterone and mineralocorticoid receptors (MRs) are associated with the pathogenesis of erectile dysfunction. However, the molecular mechanisms remain largely unknown.
Fei Wu   +6 more
doaj   +1 more source

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