Results 91 to 100 of about 119,651 (301)

Rapid Action of Aldosterone on Protein Levels of Sodium-Hydrogen Exchangers and Protein Kinase C Beta Isoforms in Rat Kidney

open access: yesInternational Journal of Endocrinology, 2017
Previous in vitro studies demonstrated that aldosterone rapidly activates sodium-hydrogen exchangers 1 and 3 (NHE 1 and 3). In vitro investigations revealed that protein kinase C (PKC) regulates NHE properties. We previously demonstrated that aldosterone
Somchit Eiam-Ong   +3 more
doaj   +1 more source

Interventional therapies for chronic heart failure: An overview of recent developments

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1081-1094, April 2025.
Abstract Heart failure (HF), the final manifestation of most cardiovascular diseases, has become a major global health concern, affecting millions of individuals. Despite basic drug treatments, patients present with high morbidity and mortality rates. However, recent advancements in interventional therapy have shown promising results in improving the ...
Bingchen Guo   +7 more
wiley   +1 more source

Diagnostic and prognostic value of pituitary-adrenal system hormones in cerebrospinal fluid of patients with acute neuroinfection

open access: yesZaporožskij Medicinskij Žurnal, 2018
The purpose of the work. To determine the diagnostic and predictive significance of the pituitary-adrenal system hormones levels in the cerebrospinal fluid of patients with acute neuroinfections due to different etiology. Materials and methods.
A. V. Sokhan
doaj   +1 more source

Left ventricular diastolic dysfunction worsens prognosis in patients with heart failure due to dilated cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1183-1193, April 2025.
Abstract Aims The prognostic significance of left ventricular (LV) diastolic dysfunction (LVDD) severity in patients with dilated cardiomyopathy (DCM) remains uncertain. This study aimed to evaluate the association of LVDD severity and elevated left atrial pressure (eLAP) with patient outcomes in stable, non‐acutely decompensated patients with DCM ...
Mateusz Winiarczyk   +12 more
wiley   +1 more source

Analysis of the usefulness and benefits of ultrafiltration in cardiorenal syndrome: A systematic review

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1194-1202, April 2025.
Abstract Aims Cardiac decompensation in cardiorenal syndrome (CRS) results in systemic congestion usually treated with diuretics. When despite high doses of diuretics, response is poor, ultrafiltration (UF) appears to be a useful and safe technique.
Borja Guerrero Cervera   +12 more
wiley   +1 more source

Association between urine aldosterone and diastolic function in patients with primary aldosteronism and essential hypertension

open access: yes, 2017
Objective: To investigate the association between aldosterone and cardiac diastolic dysfunction. ;Design and methods: We prospectively enrolled 20 patients with primary aldosteronism (PA) and 22 patients with essential hypertension (EH).
林彥宏;洪啟盛;吳允升;吳寬墩;陳盈憲;王碩盟   +1 more
core   +1 more source

eGFR slope as predictor of mortality in heart failure patients

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1217-1226, April 2025.
Abstract Aims Heart failure (HF) leads to an imbalance between heart and kidney function, resulting in poor outcomes. However, the prognostic significance of the estimated glomerular filtration rate (eGFR) trajectory in HF patients remains unclear. We analysed electronic health records (EHRs) of real‐world HF patients, assessing eGFR trajectories and ...
Sofie Verstreken   +10 more
wiley   +1 more source

Aldosterone-mediated apical targeting of ENaC subunits is blunted in rats with streptozotocin-induced diabetes mellitus.

open access: yes, 2008
BACKGROUND: Diabetes mellitus (DM) is associated with a significant polyuria and natriuesis as well as increased plasma aldosterone and anti-diuretic hormone arginine vasopressin (AVP).
Tae-Hwan Kwon (194347)   +5 more
core   +3 more sources

Aldosterone effects on glomerular structure and function [PDF]

open access: yes, 2015
Experimental evidence suggests that aldosterone directly contributes to organ damage by promoting cell growth, fibrosis, and inflammation. Based on these premises, this work aimed to assess the glomerular effects of aldosterone, alone and in combination ...
Carretta, Renzo   +21 more
core   +1 more source

Obesity, aldosterone excess, and mineralocorticoid receptor activation: Parallel or intersected circumstances?

open access: yesThe Journal of Clinical Hypertension
The obesity pandemic, with its associated comorbidities of hypertension and diabetes, constitutes a global public health issue. Importantly, there is an increasing prevalence of aldosterone excess related to obesity and resultant poor health outcomes ...
Houry Puzantian   +2 more
doaj   +1 more source

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