Results 111 to 120 of about 123,346 (302)
Aldosterone antagonism in heart failure
, 2007 Alan B MillerDivision of Cardiology, University of Florida/Jacksonville, FL, USAAbstract: Aldosterone, a neurohormone known to affect electrolytes, has recently been implicated as playing a major role in the progression of heart failure, particularly in ...
Alan B Miller
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Aldosterone-induced vasculopathy
, 2004 Aldosterone antagonists reduce mortality in chronic heart failure (CHF). An obvious question to ask is how do they do this. The prevailing hypothesis is that most of the adverse effects of aldosterone stem from its ability to produce a vasculopathy. This
Struthers, Allan D
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Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes
Journal of Intelligent Medicine, EarlyView.Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang +3 more
wiley +1 more source
, 2014 Introduction: The hereditability of insulin resistance has been demonstrated in both familial and twin studies. The effects of renin-angiotensin-aldosterone system gene polymorphisms on insulin resistance remain inconclusive.
Hsiao, Chin-Fu;Sheu, Wayne W. H.;Hung, Yi-Jen;Lin, Ming-Wei;Curb, David;Ranadex, Koustubh;Quertermous, Thomas;Chen, Yue-Ming;Chen, Ida Yi-Der;Wu, Kwan-Dun +1 more
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Journal of Pharmacy Practice and Research, EarlyView.Abstract Background Polypharmacy is a global issue, particularly among residential aged care home (RACH) residents with multimorbidity and complex care needs. However, population‐level evidence on longitudinal trends and comparisons with community‐dwelling (CD) older adults remains limited.
David Lim +4 more
wiley +1 more source
Determinants of Early Renal Function Recovery After TIPS in Patients With Portal Hypertension
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Renal dysfunction frequently occurs in patients with portal hypertension and is linked to unfavorable clinical outcomes. Transjugular intrahepatic portosystemic shunt (TIPS) has the potential to enhance renal perfusion through portal decompression; however, factors predicting early improvement in renal function remain insufficiently defined ...
Meng Jia +6 more
wiley +1 more source
Aldosterone and aldosterone receptor antagonists in patients with chronic heart failure
, 2011 Jean M Nappi, Adam SiegClinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy, Medical University of South Carolina Campus, Charleston, SC, USAAbstract: Aldosterone is a mineralocorticoid hormone synthesized by the adrenal glands that
Nappi J, Sieg
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ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions
Portal Hypertension &Cirrhosis, EarlyView.This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley +1 more source
Physiology of aldosterone and pharmacology of aldosterone blockers
, 2011 New adverse effects of aldosterone are now apparent: endothelial dysfunction, myocardial fibrosis and LV remodelling. Aldosterone blockade is able to reverse these adverse effects and so reduce mortality in heart failure.
Struthers, Allan D. +3 more
core +1 more source