Results 131 to 140 of about 123,346 (302)

Role of aldosterone availability in preeclampsia

open access: yes, 2007
Preeclampsia is a hypertensive disorder unique to pregnancy and remains the leading cause of maternal and fetal morbidity and mortality. Despite active research, the etiology of this disease remains still an enigma.
Escher, Geneviève, Mohaupt, Markus
core   +1 more source

Multi‐Target Pharmacological Mechanisms of Salvia miltiorrhiza Bunge in Metabolic Syndrome and Cardiovascular Diseases: A Comprehensive Review Based on the Theory of “Same Treatment for Different Diseases”

open access: yesPhytotherapy Research, EarlyView.
Salvia miltiorrhiza Bunge in metabolic syndrome and cardiovascular diseases: multi‐target actions on shared signaling pathways. ABSTRACT Metabolic syndrome (MetS) represents a clinical disorder characterized by the clustering of conditions including obesity, elevated blood sugar levels, and high lipid levels, which are intricately linked to the onset ...
Zhiyi Jia   +6 more
wiley   +1 more source

The role of aldosterone in heart failure and the clinical benefits of aldosterone blockade

open access: yes, 2004
Aldosterone has a variety of detrimental effects on the heart and vasculature and is increasingly recognized as an important target in chronic heart failure, as illustrated by the Randomized Aldactone Evaluation Study.
Dawson, Adelle   +2 more
core   +1 more source

Butein Attenuates Cardiac Hypertrophy by Restoring Redox–Mitochondrial Homeostasis Through Nrf2–Sirt3 Signaling

open access: yesPhytotherapy Research, EarlyView.
Butein attenuates pathological cardiac hypertrophy by activating Nrf2–Sirt3 signaling, restoring mitochondrial function and redox homeostasis. ABSTRACT Butein (3,4,2′,4′‐tetrahydroxychalcone) is a bioactive chalcone with antioxidant, anti‐inflammatory, and cytoprotective properties.
Tsendsuren Tungalag, Dong Kwon Yang
wiley   +1 more source

Aldosterone-induced salt appetite requires HSD2 neurons

open access: yesJCI Insight
Excessive aldosterone production increases the risk of heart disease, stroke, dementia, and death. Aldosterone increases both sodium retention and sodium consumption, and increased sodium consumption may worsen end-organ damage in patients with ...
Silvia Gasparini   +6 more
doaj   +1 more source

Cardiomyocyte Membrane‐Camouflaged Spinach Nano‐Thylakoids Enhance Myocardial Energy Metabolism and Ameliorate Heart Failure

open access: yesSmall, EarlyView.
Schematic illustration of the construction of MM‐NTU, its cardiac‐targeting behavior, and its light‐activated therapeutic mechanism. Thylakoids isolated from spinach chloroplasts were processed into nano‐thylakoid units (NTU) and further camouflaged with cardiomyocyte membranes to generate MM‐NTU.
Haohui Fan   +13 more
wiley   +1 more source

Advances in Unraveling the Role of the Renin-Angiotensin-AldosteroneSystem in Osteoporosis Pathogenesis

open access: yesGuoji laonian yixue zazhi
The renin-angiotensin-aldosterone system(RAAS) serves as a pivotal regulatory mechanism influencing aldosterone secretion through renin.Functioning as a hormonal cascade,RAAS plays a crucial role in maintaining dynamic homeostasis concerning arterial ...
Zige Liu, Desheng Chen
doaj   +1 more source

Aldosterone-Sensitive Cells in the Kidney: New Insights

open access: yes, 1991
Immunodetection of aldosterone receptors with a monoclonal antibody, associated with an enzyme-mediated mechanism of tissue specificity for aldosterone, allows a better definition of localization of aldosterone-sensitive cells in the kidney.
JP Bonvalet
core   +1 more source

Physiological partial aldosterone resistance in human newborns.: Aldosterone resistance at birth

open access: yes, 2009
International audienceIn the neonatal period, the human kidney is characterized by an impaired ability to regulate water and sodium homeostasis, resembling partial aldosterone resistance.
Boileau, Pascal   +13 more
core   +1 more source

Effect of plasma aldosterone concentration on serum uric acid metabolism

open access: yesGuangxi Yike Daxue xuebao
Objective To explore the associations between primary aldosteronism (PA)-related phenotypes and serum uric acid (SUA) levels as well as the risk of hyperuricemia. Methods A total of 1, 986 high-risk individuals for PA were selected from those screened at
WEI Yushuang   +8 more
doaj   +1 more source

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