Results 131 to 140 of about 119,651 (301)
ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala +1 more
wiley +1 more source
Medicine Advances, EarlyView.This article illustrates the current dilemmas of myocardial infarction patients after traditional cardiac rehabilitation, as well as the feasibility of using artificial intelligence to optimize and assist with rehabilitation programs such as by integrating mobile apps, wearables, ECGs, medication, vital signs, and assessment data; finally, the AI ...
Xinyuan Huang +6 more
wiley +1 more source
Aldosterone-induced salt appetite requires HSD2 neurons
JCI InsightExcessive aldosterone production increases the risk of heart disease, stroke, dementia, and death. Aldosterone increases both sodium retention and sodium consumption, and increased sodium consumption may worsen end-organ damage in patients with ...
Silvia Gasparini +6 more
doaj +1 more source
Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions
Portal Hypertension &Cirrhosis, EarlyView.This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley +1 more source
Effect of plasma aldosterone concentration on serum uric acid metabolism
Guangxi Yike Daxue xuebaoObjective To explore the associations between primary aldosteronism (PA)-related phenotypes and serum uric acid (SUA) levels as well as the risk of hyperuricemia. Methods A total of 1, 986 high-risk individuals for PA were selected from those screened at
WEI Yushuang +8 more
doaj +1 more source
Precision Medical Sciences, EarlyView.Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley +1 more source
Myosin Light Chain Phosphatase Plays an Important Role in Cardiac Fibrosis in a Model of Mineralocorticoid Receptor-Associated Hypertension [PDF]
三重大学博士(医学)application/pdfBACKGROUND: Myosin phosphatase targeting subunit 2 (MYPT2) is an important subunit of cardiac MLC (myosin light chain) phosphatase, which plays a crucial role in regulating the phosphorylation of MLC to phospho-MLC (p-MLC).
YE, ZHE
core +1 more source
Screening for primary aldosteronism in 1,181 Swedish primary care patients with hypertension
Frontiers in EndocrinologyObjectivePrimary aldosteronism (PA) is a common cause of hypertension. It entails elevated morbidity and mortality that do not sufficiently improve with conventional antihypertensive therapy.
Nikita Makhnov +13 more
doaj +1 more source
Phytotherapy Research, EarlyView.Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng +6 more
wiley +1 more source
Phytotherapy Research, EarlyView.Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli +6 more
wiley +1 more source