Results 141 to 150 of about 123,346 (302)

Ventilatory compensation for metabolic acidosis is independent of hypertension in dogs with chronic kidney disease

Veterinary Record, EarlyView.
Abstract Introduction Metabolic acidosis is common in dogs with chronic kidney disease (CKD) and induces ventilatory compensation. Systemic arterial hypertension frequently accompanies CKD, but its influence on the ventilatory response remains unclear.
Letícia da Silva Rueda, André Leal Raymundo Pessina, Igor Luiz Salardani Senhorello, Rodrigo Prevedello Franco, Paulo Sérgio Patto dos Santos, Maria Vitoria Magalhães Dias, Lucas Ferreira Gomes, Wagner Luis Ferreira   +7 more
wiley   +1 more source

Active renin mass concentration to determine aldosterone-to-renin ratio in screening for primary aldosteronism

, 2011
François Corbin1, Pierre Douville2, Marcel Lebel3 1Division of Biochemistry, l'Université de Sherbrooke, Sherbrooke, Quebec, Canada; 2Division of Biochemistry; 3Division of Nephrology, L'Hôtel-Dieu de Qu ...
Douville P, Corbin F, Lebel M
core  

Screening for primary aldosteronism in 1,181 Swedish primary care patients with hypertension

Frontiers in Endocrinology
ObjectivePrimary aldosteronism (PA) is a common cause of hypertension. It entails elevated morbidity and mortality that do not sufficiently improve with conventional antihypertensive therapy.
Nikita Makhnov, Nikita Makhnov, Nikita Makhnov, Jakob Skov, Jakob Skov, Tobias Åkerström, Tobias Åkerström, Fredrik Axling, Daniel Andernord, Mikael Bergenheim, Mikael Bergenheim, Mauritz Waldén, Per Hellman, Per Hellman   +13 more
doaj   +1 more source

The Aldosterone-Renin Ratio and Primary Aldosteronism [PDF]

Mayo Clinic Proceedings, 2002
Stowasser, M., Gordon, R. D.
openaire   +4 more sources

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews, Arron Lacey, Kate Bache, Emma J. Kidd   +3 more
wiley   +1 more source

Aldosterone antagonists

, 2008
Diabetes mellitus is a major risk factor for microvascular and macrovascular disease. Many of the deleterious effects of hyperglycaemia are similar to those of aldosterone on the cardiovascular system (CVS).
Parthasarathy, Hari Krishnan, MacDonald, Tom   +1 more
core   +1 more source

Metabolome Diversity Enhances Resistance of Intertidal Clams to Thermal Stress

Integrative Zoology, EarlyView.
Meretrix species are widely distributed intertidal bivalves in China with significant ecological and economic importance, which are sensitive to thermal stress. Our results showed that thermal environments of clam habitats shaped metabolome diversity, which can enhance the resistance of intertidal clams to thermal stress.
Zhi Hu, Xiang‐Tao Wei, Xiaonie Lin, Linxuan Ma, Tianzhe Zhang, Yunwei Dong   +5 more
wiley   +1 more source

Aldosterone, inflammation, and preeclampsia.

, 2005
We would like to suggest that aldosterone could play an important role in the genesis of this increased susceptibility of inflammatory process in preeclampsia. This contention comes from a number of our studies that provide rationale for this possibility.
CALO', LORENZO, ARMANINI, DECIO
core   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Renal‐vascular axis: unmasking its role in vascular endothelial growth factor‐inhibitor vascular toxicity in cancer patients

British Journal of Pharmacology, EarlyView.
Abstract Vascular toxicity is a growing concern in cancer patients receiving vascular endothelial growth factor inhibitor (VEGFi) therapy, posing a significant threat to patient prognosis. While the primary mechanism of VEGFi‐induced vascular toxicity is linked to redox‐sensitive reactions that disrupt vascular tone, leading to hypertension and ...
Grace Whelan, Karla B. Neves
wiley   +1 more source