Results 161 to 170 of about 123,346 (302)

Risk Factors for Implant Failure and Peri‐Implantitis: A Retrospective Cohort Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This retrospective cohort study evaluated patient‐, implant‐, site‐, procedural‐, biological‐, and prosthesis/mechanics‐related factors associated with early and late implant failure and peri‐implantitis. Material and Methods Electronic health record data from a university center were analyzed.
Nathalia Vilela, Bruno C. V. Gurgel, Hélio D. P. da Silva, Claudio M. Pannuti, Poliana M. Duarte   +4 more
wiley   +1 more source

The Aldosterone-Immune Axis in Primary Aldosteronism: Linking Adrenal Pathogenesis to Systemic Inflammation and Target-Organ Damage. [PDF]

Biomedicines
Zaidi NE, Azizan EA, Ali A.
europepmc   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

Selective inhibition of aldosterone production modulates human adrenocortical (HAC15) cell fate. [PDF]

Front Endocrinol (Lausanne)
Long KC, Aminuddin A, Ajlaa Ayub N, Tan GC, Jamal ARA, Abdul Murad NA, Johdi NA, Gomez-Sanchez CE, Sukor N, Brown MJ, Azizan EA.   +10 more
europepmc   +1 more source

Multisystem developmental abnormalities and insulin resistance in ADTKD‐HNF1B with the p.E105K variant: A clinical conundrum

Diabetic Medicine, EarlyView.
Abstract Aims HNF1B variants cause autosomal dominant tubulointerstitial kidney disease (ADTKD‐HNF1B), but the phenotypic spectrum of variants of uncertain significance (VUS) remains incompletely defined. We aimed to characterise the multisystem phenotype associated with the HNF1B p.E105K variant and to examine the mechanism underlying insulin ...
YunZe Wang, KangChun Xu, PengFei Liu, Bin Wang, Yan Yang, ShanZhai Wei   +5 more
wiley   +1 more source

Early sodium‐glucose co‐transporter 2 inhibitor initiation is associated with improved cardiovascular outcomes in type 2 diabetes and acute coronary syndrome

Diabetic Medicine, EarlyView.
Abstract Aims Sodium‐glucose co‐transporter 2 inhibitors have demonstrated cardiovascular benefits in individuals with type 2 diabetes mellitus, but the optimal timing of initiation in those with acute coronary syndrome is not known. This study aims to assess if early therapy at discharge is superior to delayed or no therapy in reduction in major ...
Muhammad Usman Shah, Joanna Kate Ward, Alun Roebuck, Bala Srinivasan, Paul Edward Squires, Claire Elizabeth Hills, Maxime Inghels, Kelvin Lee   +7 more
wiley   +1 more source

Aldosterone-Producing Lesions Harboring <i>ATP1A1</i> and <i>ATP2B3</i> Mutations: An International Multicenter Study. [PDF]

Hypertension
Vibhatavata P, Liu Y, Almeida MQ, Amar L, Bancos I, Baron S, Butz F, Cohen DL, Culver SA, Fernandes-Rosa FL, Guimaraes AG, Hamrahian AH, Hu J, Kroiss M, Luther JM, Oettle MF, Osman I, Pariente B, Puar TH, Rege J, Satoh F, Scholl U, Stowasser M, Tezuka Y, Udager AM, Vaidya A, van Rooyen D, Wachtel H, Williams TA, Wu VC, Wu CY, Zennaro MC, Young WF, Rainey WE, Turcu AF.   +34 more
europepmc   +1 more source

Real‐world observational study evaluating metabolic and kidney outcomes in patients living with chronic kidney disease and type 2 diabetes mellitus with obesity prescribed tirzepatide

Diabetic Medicine, EarlyView.
Abstract Background Obesity and type 2 diabetes mellitus (T2DM) accelerate chronic kidney disease (CKD) progression. Tirzepatide, a dual glucagon‐like peptide‐1 (GLP‐1) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonist, has demonstrated metabolic and potential renoprotective benefits in clinical trials.
Jack E. Carruthers, Xi Yan Ooi, Dawn Goodall, Jo Reed, Rachna Bedi, Adrian McGrath, Michelle Willicombe, Parizad Avari, Andrew H. Frankel   +8 more
wiley   +1 more source

Kidney Outcomes With GLP‐1 Receptor Agonists and Tirzepatide Versus Finerenone in Type 2 Diabetes and Chronic Kidney Disease: A Real‐World Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To compare kidney outcomes after GLP‐1 receptor agonists (RA) or tirzepatide (GLP‐1/GIP RAs) versus finerenone initiation in adults with Type 2 diabetes (T2D) and moderate chronic kidney disease (CKD). Methods In a retrospective TriNetX global network study (July 2021–November 2025), adults with T2D and CKD stages 3–4 initiating GLP‐1/GIP ...
Dvora R. Sehtman‐Shachar, Alisa Fishkin, Gil Leibowitz, Ofri Mosenzon, Meir Schechter, Genya Aharon‐Hananel   +5 more
wiley   +1 more source

Aldosterone-mediated apical targeting of ENaC subunits is blunted in rats with streptozotocin-induced diabetes mellitus.

, 2008
BACKGROUND: Diabetes mellitus (DM) is associated with a significant polyuria and natriuesis as well as increased plasma aldosterone and anti-diuretic hormone arginine vasopressin (AVP).
Tae-Hwan Kwon (194347), Søren Nielsen (155815), Heidi O'Neill (7949969), Patrick B. Collins (7949858), Jørgen Frøkiaer (550699), Janne Lebeck (7949972)   +5 more
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