Results 181 to 190 of about 89,390 (263)

Association between aldosterone and the risk of cardiovascular disease in hypertensive patients: a cohort study. [PDF]

Front Endocrinol (Lausanne)
Gan L, Li N, Heizhati M, Wang H, Yao L, Cai L, Liu S, Hong J, Zhang D.   +8 more
europepmc   +1 more source

Augmenting erythropoiesis using recombinant human erythropoietin at sea level blunts the high altitude induced increase in erythropoiesis

The Journal of Physiology, EarlyView.
Abstract figure legend Pharmacologically augmenting erythropoiesis with rEPO at sea level blunts the high altitude induced erythropoiesis. Abstract Erythropoiesis increases with high altitude (HA) acclimatization. Recombinant human erythropoietin (rEPO) induces erythropoiesis.
Roy M. Salgado, Thomas A. Mayer, Gabrielle E. W. Giersch, Billie K. Alba, David E. Barney Jr, Aaron R. Caldwell, Nisha Charkoudian, Brandon M. Roberts, Afton D. Seeley, K. Riley Connor, Andrew M. Greenfield, Adam J. Luippold, Mark L. Plamper, Jermaine A. Ward, Shauna M. Ward, Benjamin J. Ryan   +15 more
wiley   +1 more source

Chemerin Activation of Toll-Like Receptor 4 Drives Mineralocorticoid Receptor-Mediated Aortic Valve Remodeling in Chronic Kidney Disease. [PDF]

J Am Heart Assoc
Sánchez-Bayuela T, Soulié M, Garaikoetxea M, Fernández-Celis A, López-Andrés N, Jaisser F.   +5 more
europepmc   +1 more source

Unveiling the role of the venous system in arterial hypertension: A computational study

The Journal of Physiology, EarlyView.
Abstract figure legend This abstract figure summarizes the principal findings of our computational analysis of hypertension. Model‐based results identify reduced venous compliance as a major determinant of elevated arterial pressure, second only to increased peripheral resistance.
Eleuterio F. Toro, Lucas O. Müller, Tonja W. Emans, Fiona D. McBryde, Julian F. R. Paton   +4 more
wiley   +1 more source

⁶⁸GA-Pentixafor PET/CT: a non-invasive molecular alternative to adrenal venous sampling in primary aldosteronism. [PDF]

EJNMMI Rep
Bambhroliya P, Agrawal K, Parida GK, Gnanasegaran G.   +3 more
europepmc   +1 more source

Translating cardiovascular ion channel and Ca2+ signalling mechanisms into therapeutic insights

The Journal of Physiology, EarlyView.
Abstract figure legend This white paper integrates mechanistic discoveries across ion channel biology, Ca2+ signalling and multiscale cardiovascular physiology to highlight new opportunities for accelerating research and guiding next‐generation therapies. Printed with permission from ®Anita Impagliazzo Medical Illustration. [Correction added on 2 March
Silvia Marchianò, Miguel Martín‐Aragón Baudel, Charlotte E. R. Smith, Gonzalo Hernandez Hernandez, Donald M. Bers, Patrick M. Boyle, Dobromir Dobrev, Shanna Hamilton, Osama F. Harraz, Na Li, Thomas A. Longden, William E. Louch, Madeline Nieves‐Cintron, Matthew A. Nystoriak, Walter Lee Murfee, Przemysław B. Radwański, Swapnil K. Sonkusare, Manuel F. Navedo, Eleonora Grandi   +18 more
wiley   +1 more source

The non-steroidal mineralocorticoid receptor blocker esaxerenone reduces glomerular hyperfiltration and albuminuria. [PDF]

Nephrol Dial Transplant
Tatsugawa R, Kidokoro K, Iwakura T, Hirano A, Kajimoto E, Takasu M, Wada M, Kitao H, Wada Y, Gyarmati G, Kishi S, Nagasu H, Cherney DZI, Peti-Peterdi J, Sasaki T, Kashihara N.   +15 more
europepmc   +1 more source

Circulating microRNA signatures reveal core and reversible dysregulation in obesity via machine learning

The Journal of Physiology, EarlyView.
Abstract figure legend Machine learning analysis of circulating microRNA (miRNA) profiles identified a minimal set of biomarkers that distinguish individuals with obesity from lean individuals both before and after weight‐loss intervention. Comparative analyses revealed heterogeneous molecular responses to weight reduction, with some miRNAs showing ...
Yuan Yue, Rajesh Katare, Jeremiah Deng, Daniel Alencar Da Costa, Patrick Manning   +4 more
wiley   +1 more source

Increased Frequency and Distinct Genotypic Patterns of Somatic Aldosterone-Driver Mutations in Aldosterone-Producing Micronodules from Primary Aldosteronism Patients. [PDF]

Endocr Pathol
Lim JS, Wu CY, Qin Z, Liu CJ, van Rooyen D, Sapiro DR, Giordano TJ, Turcu AF, Rainey WE, Udager AM.   +9 more
europepmc   +1 more source

Design‐Assisted Chemometric UV Spectrophotometric Determination of Candesartan Cilexetil, Chlorthalidone and Amlodipine Using Principal Component Regression, Partial Least Squares and Genetic Algorithm‐Partial Least Squares Models

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT This study presents a sustainable chemometric‐assisted UV spectrophotometric strategy for the simultaneous determination of candesartan cilexetil (CAN), chlorthalidone (CTL) and amlodipine (AML) in laboratory‐prepared mixtures and commercial pharmaceutical formulations.
Khanda F. M. Amin, Samar H. Elagamy, Reem H. Obaydo, Hayam M. Lotfy   +3 more
wiley   +1 more source