Results 191 to 200 of about 123,346 (302)

Doxorubicin‐induced Cardiotoxicity in Dogs: A Narrative Review

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Doxorubicin, an anthracycline widely used in both human and veterinary oncology, is highly effective against a variety of malignancies in dogs, including lymphomas, sarcomas and carcinomas. Despite its efficacy, doxorubicin exposure can be associated with cardiotoxicity, which may present acutely or chronically, potentially leading to severe ...
Supita Sunpongsri, Tom Roos, Ronette Gerhing, Maurice Zandvliet, Giorgia Santarelli   +4 more
wiley   +1 more source

GPER and EGFR cross-talk highlight aldosterone- and MR antagonist-induced NO production in cultured endothelial cells. [PDF]

Front Pharmacol
Paredes R, Donoso MV, Lagos CF, Cárdenas C, Acuña-Castillo C, Valdes D, Constandil L, Huidobro-Toro JP.   +7 more
europepmc   +1 more source

Influence of menstrual cycle phase on inflammatory and vascular responses to acute passive heating in healthy young women

Experimental Physiology, EarlyView.
Abstract The aim of this study was to determine whether inflammatory and vascular responses to passive heating differ between the early follicular phase (EFP) and the mid‐luteal phase (MLP) of the menstrual cycle. Ten healthy, naturally menstruating females (26 ± 3 years of age; body mass index 21.4 ± 1.9 kg/m2) were assessed during EFP and MLP ...
Yunuo Su, Emma O'Donnell, Stephen J. Bailey, Christof A. Leicht   +3 more
wiley   +1 more source

From bench to bedside: primary aldosteronism revisited. [PDF]

Endocr Connect
Wei J, Williams TA.
europepmc   +1 more source

Seven days of mixed‐method heat acclimation improved markers of cardiovascular and fluid‐regulatory strain during exercise‐heat stress

Experimental Physiology, EarlyView.
Abstract A mixed‐method heat acclimation (HA) protocol may optimise performance by supporting the training taper while promoting thermal adaptation; however, the impact on cardiovascular and fluid‐regulatory adjustments to protect health is unknown. Therefore, we examined the effects of a mixed‐method heat protocol on physiological responses, including
Daniel Snape, Barney Wainwright, Iain T. Parsons, Michael J. Stacey, David R. Woods, John O'Hara   +5 more
wiley   +1 more source

Renin-Angiotensin-Aldosterone Axis Activity in Women with Chronic Endometritis: A Prospective Observational Study. [PDF]

Int J Mol Sci
Garbin G, Marin L, Sabbadin C, Gullo G, Armanini D, Bordin L, Ragazzi E, Ambrosini G, Andrisani A.   +8 more
europepmc   +1 more source

Sodium–glucose cotransporter 2 inhibitors for hypertension in cardiovascular–kidney–metabolic syndrome

Experimental Physiology, EarlyView.
Abstract The antihypertensive mechanism of sodium–glucose cotransporter 2 (SGLT2) inhibitors has been traditionally attributed to osmotic diuresis. However, emerging evidence reveals multifaceted mechanisms beyond diuresis, including regulation of the renin–angiotensin–aldosterone system, sympathetic nervous system suppression, ion homeostasis ...
Chunxiang Xu, Xingyu Qiu, Nan Xu, Gensheng Zhang, Enyin Lai, Liang Zhao   +5 more
wiley   +1 more source

Association of Hypertension and Serum Aldosterone Levels in Male Patients with Androgenetic Alopecia: A Case-Control Study. [PDF]

J Multidiscip Healthc
Alhetheli G, Almarshoud SS, Ghorab A, Aldawish R, Aldawsari A, Alowais A.   +5 more
europepmc   +1 more source

Contributions of vascular ageing to late‐onset Alzheimer's disease

Experimental Physiology, EarlyView.
Abstract Late‐onset Alzheimer's disease (LOAD) is an age‐related disease that is strongly associated with vascular risk factors and cerebrovascular impairments. As such, changes in the vasculature with advancing age likely contribute to LOAD, but the mechanisms underlying these contributions remain incompletely understood.
Skylyn J. Ferguson, Young Deanna Choi, Ashley E. Walker   +2 more
wiley   +1 more source

Klotho Deficiency Impairs Distal Potassium Homeostasis Through mTORC1-Dependent Suppression of ROMK. [PDF]

Acta Physiol (Oxf)
Kawarazaki W, Ayuzawa N, Nishimoto M, Hirohama D, Ueda K, Marumo T, Fujita T.   +6 more
europepmc   +1 more source