Results 121 to 130 of about 123,346 (302)

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Development and aldosterone regulation of sodium transport in the chick (Gallus domesticus) allantoic epithelium

, 2001
textThe chick allantoic epithelium, an extraembryonic membrane, encases the waste fluid generated by the kidney. Volume and ionic composition of the allantoic fluid change dramatically over development.
Machart, Jan Melton
core  

Non-Hypertensive Effects of Aldosterone [PDF]

Aldosterone, the primary adrenal mineralocorticoid hormone, as an integral part of the renin–angiotensin–aldosterone system (RAAS), is crucial in blood pressure regulation and maintaining sodium and potassium levels.
Dorota Dworakowska, Jacek Wolf, Ashley B. Grossman, Natalia Ekman, Łukasz Jędrzejewski, Anna Nieckarz   +5 more
core   +1 more source

Plasma Steroid Trajectories From Day‐of‐Surgery Baseline After Robot‐Assisted Radical Prostatectomy for Prostate Cancer

The Prostate, EarlyView.
ABSTRACT Background Circulating steroid trajectories after robot‐assisted radical prostatectomy are poorly characterized from the day‐of‐surgery baseline, and relevant biology extends beyond testosterone and dihydrotestosterone to adrenal‐derived 11‐oxygenated androgens and steroid conjugate turnover.
Jiri Heracek, Lukas Gadus, Michal Horenitzky, Marie Novakova, Tereza Skodova, Lucie Kolatorova, Anezka Varausova, Adela Lukaskova, Jana Vitku   +8 more
wiley   +1 more source

Aldosterone, aldosterone receptor blockers and chronic kidney disease

Zdravniški Vestnik, 2011
Chronic kidney disease (CKD) is a worldwide public health problem and an important risk factor for cardiovascular events, morbidity and mortality. The renin-angiotensin-aldosteron system (RAAS) drugs, angiotensin-converting enzyme inhibitors and/or ...
Sebastjan Bevc
doaj  

Case Report: Autoimmune hepatitis in a patient with pseudohypoaldosteronism type 1—insights into a rare co-occurrence

Frontiers in Pediatrics
BackgroundPseudohypoaldosteronism (PHA) type 1 is a rare disease characterized by an end-organ unresponsiveness to mineralocorticoids, which results in salt loss from the kidney and impaired potassium and hydrogen secretion.
Hanan Al Thiabat, Jafar Alsheyyab, Israa Waleed Khalid, Rafeef Abdel Razzaq, Kamleh Barham, Hanaa M. Algharaibeh, Eyad Altamimi   +6 more
doaj   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Aldosterone induces Ras methylation in A6 epithelia

, 2000
Aldosterone increases Na+reabsorption by renal epithelial cells: the acute actions (<4 h) appear to be promoted by protein methylation. This paper describes the relationship between protein methylation and aldosterone's action and describes ...
G. Yue, J. D. Stockand, O. K. Al-Khalili, D. C. Eaton, N. F. Al-Baldawi   +4 more
core   +1 more source

Recent Advances and Perspectives on the Use of Mineralocorticoid Receptor Antagonists for the Treatment of Hypertension and Chronic Kidney Disease: A Review

Biomedicines
Chronic kidney disease (CKD) is a major public health concern around the world. It is a significant risk factor for cardiovascular disease (CVD), and, as it progresses, the risk of cardiovascular events increases.
Kisho Miyasako, Yujiro Maeoka, Takao Masaki   +2 more
doaj   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source