Simulation-based cost-utility analysis of population screening-based alendronate use in Switzerland [PDF]
, 2018 Summary: A simulation model adopting a health system perspective showed population-based screening with DXA, followed by alendronate treatment of persons with osteoporosis, or with anamnestic fracture and osteopenia, to be cost-effective in Swiss ...
Lippuner, K., Schwenkglenks, M.
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Including patient choice in cost-effectiveness decision rules [PDF]
There has been increasing discussion in the economic literature about the appropriateness of using general population values within technology appraisal.
Dixon, S.
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Türk Osteoporoz Dergisi, 2006 This study was to compare and research the effects of alendronate and calcitonin treatments with 2 years duration in women with postmenopausal osteoporosis.
Gülcan Gürer +3 more
doaj
Cost-effectiveness of alendronate in the treatment of osteoporois in Denmark: An economic evaluation based on the fracture intervention trial [PDF]
, 2002 Background: The Fracture Intervention Trial (FIT) showed that the bisphosphonate alendronate reduces the risk of fractures in women with low bone mass in the United States. Objective: To estimate the cost-effectiveness (cost per life-year gained and cost
Borgström, Fredrik +2 more
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A critical structured review of economic evaluations of interventions for the prevention and treatment of osteoporosis [PDF]
Osteoporosis is a major cause of morbidity, mortality and resource cost amongst the elderly population. Hip fracture is the most serious of the osteoporotic fractures, with approximately 10-20% of patients dying within six months of sustaining a fracture.
Bernie O'Brien +3 more
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Effects of strontium ranelate and alendronate on bone microstructure in women with osteoporosis: Results of a 2-year study [PDF]
, 2018 Summary: Strontium ranelate appears to influence more than alendronate distal tibia bone microstructure as assessed by high-resolution peripheral quantitative computed tomography (HR-pQCT), and biomechanically relevant parameters as assessed by micro ...
Bock, O. +9 more
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Systems biology strategy for drug potentiating through drug repurposing:bisphosphonates beyond osteoporosis treatment [PDF]
, 2018 Goltsov, Alexey +2 more
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β-arrestin/connexin 43 complex anchors ERKs outside the nucleus: a pre-requisite for bisphosphonate anti-apoptotic effect mediated by CX43/ERK in osteocytes [PDF]
, 2016 Bisphosphonates (BPs) anti-fracture ef cacy may be due in part to inhibition of osteocyte apoptosis. This effect requires opening of con- nexin (Cx) 43 hemichannels and phosphoryla- tion of the extracellular signal regulated kinases (ERKs).
Bellido, Teresita +2 more
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Cost-Effectiveness of Alendronate in the Treatment of Osteoporosis in Denmark - An Economic Evaluation Based on the Fracture Intervention Trial [PDF]
Background: The Fracture Intervention Trial (FIT) showed that the bisphosphonate alendronate reduces the risk of fractures in women with low bone mass in the United States. Objective: To estimate the cost-effectiveness (cost per life-year gained and cost
Borgström, Fredrik +2 more
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Progress in OrthodonticsBackground Osteogenesis imperfecta (OI) is a genetic disorder of connective tissue caused by mutations associated with type I collagen, which results in defective extracellular matrix in temporomandibular joint (TMJ) cartilage and subchondral bone.
Po-Jung Chen +3 more
doaj +1 more source