Results 81 to 90 of about 29,370 (221)

The comparative evaluation of 1% alendronate gel as local drug delivery system in chronic periodontitis in smokers and non smokers: Randomized clinical trial

Journal of Oral Biology and Craniofacial Research, 2019
Introduction: Periodontitis is a progressive disease of microbial origin involving the loss of supporting tissues of the teeth resulting from host inflammatory and immunologic reactions.
Vidushi Sheokand, Vandana Srikrishna Chadha, Pooja Palwankar   +2 more
doaj   +1 more source

Influence of Prednisolone and Alendronate on the de novo Mineralization of Zebrafish Caudal Fin

JBMR Plus, 2021
Dysregulated balance between bone resorption and formation mediates the onset and progression of osteoporosis. The administration of prednisolone is known to induce osteoporosis, whereas alendronate is commonly used to reverse the process.
Fabio Rocha Bohns, Yann‐Rong Shih, Yung‐Jen Chuang, Riaz Akhtar, Po‐Yu Chen   +4 more
doaj   +1 more source

Effects of 24 months of treatment with romosozumab followed by 12 months of denosumab or placebo in postmenopausal women with low bone mineral density : a randomized, double-blind, phase 2, parallel group study [PDF]

, 2018
Over 12 months, romosozumab increased bone formation and decreased bone resorption, resulting in increased bone mineral density (BMD) in postmenopausal women with low BMD (NCT00896532).
Binkley, Bone, Cosman, Cummings, Harrington, Heiss, Langdahl, Leder, Li, Li, McClung, Ominsky, Padhi, Papapoulos, Recknor, Saag, van Bezooijen, Wasnich   +17 more
core   +2 more sources

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source

Efficacy of generic alendronate and ibandronate in post menopausal osteoporosis

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2012
Objective: To determine whether generic non innovator once weekly oral alendronate is as effective as the innovator once oral Ibandronate.Method: This was an open label, prospective, randomized control trial conducted at the endocrine unit at the ...
NP Somasundaram, NI Thalagala, DMMK Saranapala, MR Sumanatilleke, CN Antonypillai   +4 more
doaj   +1 more source

Bisphosphonate's and Intermittent Parathyroid Hormone's Effect on Human Spinal Fusion: A Systematic Review of the Literature. [PDF]

, 2017
There has been a conscious effort to address osteoporosis in the aging population. As bisphosphonate and intermittent parathyroid hormone (PTH) therapy become more widely prescribed to treat osteoporosis, it is important to understand their effects on ...
Acosta, Frank L, Hah, Raymond, Hsieh, Patrick C, Iorio, Justin A, Jakoi, Andre M, Liu, John C, Patel, Neil N, Pham, Martin H, Stone, Michael A, Wang, Jeffrey C   +9 more
core   +2 more sources

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

Can Knee Arthroscopy Be Considered Entirely Safe for Patients Over 50 Years Old With no Risk of Osteonecrosis? Case Series and Literature Review on Post‐Artrhoscopy Osteonecrosis of the Knee (PAONK)

Orthopaedic Surgery, Volume 17, Issue 5, Page 1378-1388, May 2025.
Post‐arthroscopy osteonecrosis is a rare complication occurring in 0.82% of cases, primarily affecting patients over 50 with degenerative meniscal tears. Early detection through MRI and conservative treatment, including bisphosphonates and weight‐bearing avoidance, proved effective in most cases, while some required surgical intervention.
Panagiotis Ntagiopoulos, Georgios Kalinterakis, Pierrenzo Pozzi, Dimitris Fligkos, George Themistocleous, Sotirios Themistokleous, Triantafyllia Dimou, Riccardo Compagnoni, Paolo Ferrua, Pietro Simone Randelli   +9 more
wiley   +1 more source

The effects of sodium alendronate on socket healing after tooth extraction: a systematic review of animal studies [PDF]

Brazilian Oral Research
The aim of this systematic review was to answer the following question: “Does alendronate, a nitrogen-containing bisphosphonate, improve or impair alveolar socket healing after tooth extraction in animal models”?
Nilo Guliberto Martins CHAVARRY, Pedro Villas Boas ABREU, Eduardo Jorge FERES-FILHO, Daniele Masterson Tavares PEREIRA, Lucianne Cople MAIA, Rafael Scaf De MOLON   +5 more
doaj   +1 more source

Effect of alendronate on post-traumatic osteoarthritis induced by anterior cruciate ligament rupture in mice. [PDF]

, 2015
IntroductionPrevious studies in animal models of osteoarthritis suggest that alendronate (ALN) has antiresorptive and chondroprotective effects, and can reduce osteophyte formation.
Anderson, Matthew J, Christiansen, Blaine A, Diko, Sindi, Genetos, Damian C, Haudenschild, Dominik R, Hsia, Allison W, Khorasani, Mohammad S   +6 more
core   +1 more source