Results 61 to 70 of about 18,251 (231)

Randomized clinical trial comparing efficacy and safety of brand versus generic alendronate (Bonmax®) for osteoporosis treatment. [PDF]

PLoS ONE, 2017
Although the same efficacy and tolerability are anticipated due to both drugs containing the same active ingredients, comparative studies between brand and generic alendronate are limited.
Aasis Unnanuntana, Atthakorn Jarusriwanna, Panupan Songcharoen   +2 more
doaj   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source

Efficacy of generic alendronate and ibandronate in post menopausal osteoporosis

Sri Lanka Journal of Diabetes Endocrinology and Metabolism, 2012
Objective: To determine whether generic non innovator once weekly oral alendronate is as effective as the innovator once oral Ibandronate.Method: This was an open label, prospective, randomized control trial conducted at the endocrine unit at the ...
NP Somasundaram, NI Thalagala, DMMK Saranapala, MR Sumanatilleke, CN Antonypillai   +4 more
doaj   +1 more source

Cost-Effectiveness of Zoledronic Acid Versus Oral Alendronate for Postmenopausal Osteoporotic Women in China

Frontiers in Pharmacology, 2020
ObjectiveThis study aims to estimate the cost-effectiveness of yearly intravenous zoledronic acid treatment versus weekly oral alendronate for postmenopausal osteoporotic women in China.MethodsWe used a Markov microsimulation model to compare the cost ...
Ruxu You, Yu Zhang, David Bin-Chia Wu, Jinyu Liu, Xinyu Qian, Nan Luo, Takahiro Mori, Takahiro Mori, Takahiro Mori   +8 more
doaj   +1 more source

Combined Effects of Romosozumab and Zoledronate on the Development of Osteonecrosis of the Jaw

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to assess the occurrence of medication‐related osteonecrosis of the jaw (MRONJ) in mice following the sequential administration of romosozumab and zoledronate and to confirm their inhibitory effects on osteoclast differentiation in vitro.
Hae‐Seo Park, Shihyun Kim, Seo‐Yeong An, Reuben H. Kim, Jongho Choi, Moon‐Young Kim   +5 more
wiley   +1 more source

Ten years' experience with alendronate for osteoporosis in postmenopausal women

, 2004
Background: Antiresorptive agents are widely used to treat osteoporosis. We report the results of a multinational randomized, double-blind study, in which postmenopausal women with osteoporosis were treated with alendronate for up to 10 years.
Alendronate Phase II Osteoporosis, Hosking, D., Devogelaer, J, Bone, HG, Rodriguez-Portales, JA, Hosking, D, Santora, AC, Rodriguez Portales, JA, Tonino, RP, Liberman, UA, Tucci, JR, Downs, RW, Devogelaer, Jean-Pierre, Gupta, J, Emkey, RD   +14 more
core   +1 more source

Gastric and Duodenal Safety of Daily Alendronate [PDF]

, 2002
BackgroundIsolated case reports of gastric ulcers after alendronate sodium use raised concern about the gastroduodenal safety of daily alendronate.
Levin, TR, Boles, Myde, Carey, Vincent J, Gurwitz, Jerry H, Chan, K Arnold, Andrade, Susan E, Chase, Gary A, Buist, Diana SM, Beck, Arne, Ettinger, Bruce, Goodman, Michael, Guess, Harry A, Donahue, James G, Platt, Richard, Chandler, Julie M, LaCroix, Andrea Z, Fishman, Paul   +16 more
core   +1 more source

Seizures after alendronate

JRSM, 2002
Alendronate and other bisphosphonates are effective in the prevention and treatment of osteoporosis by inhibiting bone resorption. In normal circumstances a small initial fall in serum calcium has no clinical consequences because it is corrected by an increase in parathyroid hormone (PTH) secretion1.
Richard J, Maclsaac, Ego, Seeman, George, Jerums   +2 more
openaire   +3 more sources

Can Knee Arthroscopy Be Considered Entirely Safe for Patients Over 50 Years Old With no Risk of Osteonecrosis? Case Series and Literature Review on Post‐Artrhoscopy Osteonecrosis of the Knee (PAONK)

Orthopaedic Surgery, Volume 17, Issue 5, Page 1378-1388, May 2025.
Post‐arthroscopy osteonecrosis is a rare complication occurring in 0.82% of cases, primarily affecting patients over 50 with degenerative meniscal tears. Early detection through MRI and conservative treatment, including bisphosphonates and weight‐bearing avoidance, proved effective in most cases, while some required surgical intervention.
Panagiotis Ntagiopoulos, Georgios Kalinterakis, Pierrenzo Pozzi, Dimitris Fligkos, George Themistocleous, Sotirios Themistokleous, Triantafyllia Dimou, Riccardo Compagnoni, Paolo Ferrua, Pietro Simone Randelli   +9 more
wiley   +1 more source

Simulation-based cost-utility analysis of population screening-based alendronate use in Switzerland [PDF]

, 2007
A simulation model adopting a health system perspective showed population-based screening with DXA, followed by alendronate treatment of persons with osteoporosis, or with anamnestic fracture and osteopenia, to be cost-effective in Swiss postmenopausal ...
Lippuner, Kurt, Schwenkglenks, M
core   +1 more source