Results 61 to 70 of about 29,370 (221)

Estradiol replacement attenuates alendronate‐associated adverse effects on alveolar bone repair in ovariectomized rats

Journal of Periodontology, EarlyView.
Abstract Background Sodium alendronate (ALN) is widely used to treat postmenopausal osteoporosis, but both estrogen deficiency and antiresorptive therapy may impair alveolar bone repair after tooth extraction. A clinically relevant but insufficiently explored scenario involves estrogen‐deficient individuals receiving hormone replacement therapy (HRT ...
Pedro H. C. Isaias, Paulo G. B. Silva, Isabelly V. do Nascimento, Raul A. D. A. da Silva, Thayla M. do C. Sousa, Ana J. A. de de Vasconcelos, José V. M. Lemos, Fabrício B. Sousa, Ana P. N. N. Alves, Mário R. L. Mota   +9 more
wiley   +1 more source

Impregnation of bone chips with alendronate and cefazolin, combined with demineralized bone matrix: a bone chamber study in goats

BMC Musculoskeletal Disorders, 2012
Background Bone grafts from bone banks might be mixed with bisphosphonates to inhibit the osteoclastic response. This inhibition prevents the osteoclasts to resorb the allograft bone before new bone has been formed by the osteoblasts, which might prevent
Mathijssen Nina MC, Hannink Gerjon, Pilot Peter, Schreurs B Wim, Bloem Rolf M, Buma Pieter   +5 more
doaj   +1 more source

Supplement With Calcium or Alendronate Suppresses Osteopenia Due to Long Term Rabeprazole Treatment in Female Mice: Influence on Bone TRAP and Osteopontin Levels

Frontiers in Pharmacology, 2020
Background and PurposeRabeprazole, a proton pump inhibitor (PPIs) is much endorsed to patients with increased gastric acidity. PPIs were accused to have osteoporotic effects on patients who chronically use them. The point of the current investigation was
Aly A.M. Shaalan, Aly A.M. Shaalan, Mohamed El-Sherbiny, Mohamed El-Sherbiny, Taghrid B. El-Abaseri, Mohamed Z. Shoaeir, Tarek M. Abdel-Aziz, Magda I. Mohamed, Sawsan A. Zaitone, Sawsan A. Zaitone, Hala M. F. Mohammad, Hala M. F. Mohammad   +11 more
doaj   +1 more source

Effects of Dual Wavelength Photobiomodulation on Osseointegration in Grafted Areas

Lasers in Surgery and Medicine, EarlyView.
ABSTRACT Objective This study evaluated the effects of dual‐wavelength photobiomodulation (PBMT) (infrared and red laser) on osseointegration and bone structure in areas grafted with deproteinized bovine bone (DBB). Methods Sixty‐four rats were randomly distributed into four groups. The groups were divided according to the irradiation protocol applied:
Lucas de Sousa Goulart Pereira, Julia Raulino Lima, Elcio Marcantonio Jr., Priscilla Barbosa Ferreira Soares, Suzane Cristina Pigossi, Guilherme José Pimentel Lopes de Oliveira   +5 more
wiley   +1 more source

Mind the Gap: Predictors of Osteoporosis Treatment Following Fragility Fracture in Parkinsonism

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Fracture risk is increased in Parkinson's yet this risk is often not addressed. Objectives Our objective was to study the extent to which osteoporosis was treated, and predictors of treatment in a large representative cohort with parkinsonism.
Katie C. Naylor, Emily J. Henderson, Emma Tenison   +2 more
wiley   +1 more source

Favorable therapeutic response of osteoporosis patients to treatment with intravenous zoledronate compared with oral alendronate [PDF]

, 2015
Objectives: To evaluate the efficacy of orally-administered alendronate compared with intravenously-administered zoledronate. Methods: This prospective study was carried out at Barts Health HNS Trust between April 2010 and March 2012.
Akanle, OA, Al-Adhoubi, NK, Al-Bogami, MM, Alkhorayef, MA, Bystrom, J, Jawad, AS, Mageed, RA   +6 more
core   +4 more sources

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

Medicinal Research Reviews, EarlyView.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo, Shinwon Kang, Jae Eun Yang, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Biochemical bone biomarkers in plasma cell dyscrasias

British Journal of Haematology, EarlyView.
Visual abstract depicting that bone turnover markers reflect dynamic alterations in bone remodelling across the spectrum of plasma cell dyscrasias but remain limited by assay variability, biological confounding and incomplete integration with imaging and risk stratification.
Guido Nador, Rohit Vijjhalwar, Muhammad Kassim Javaid, Claire M. Edwards, Karthik Ramasamy   +4 more
wiley   +1 more source

Combination therapy of curcumin and alendronate modulates bone turnover markers and enhances bone mineral density in postmenopausal women with osteoporosis

Archives of Endocrinology and Metabolism
Objective: This study evaluated the effects of combination therapy of curcumin and alendronate on BMD and bone turnover markers in postmenopausal women with osteoporosis. Subjects and methods: In a randomized, double-blind trial study, 60 postmenopausal
Fatemeh Khanizadeh, Asghar Rahmani, Khairollah Asadollahi, Mohammad Reza Hafezi Ahmadi   +3 more
doaj   +1 more source

Comparing tolerability and efficacy of generic versus brand alendronate: a randomized clinical study in postmenopausal women with a recent fracture. [PDF]

PLoS ONE, 2013
INTRODUCTION:An increasing number of generic alendronate formulations have become available. Although expected to have the same tolerability and efficacy, head-to head comparison of generic and brand alendronate was never performed.
Joop P W van den Bergh, Marian E Bouts, Eveline van der Veer, Robert Y van der Velde, Marcel J W Janssen, Piet P Geusens, Bjorn Winkens, Nico J J Oldenhof, Tineke A C M van Geel   +8 more
doaj   +1 more source