Results 41 to 50 of about 29,370 (221)
Alendronate induces anti-migratory effects and inhibition of neutral phosphatases in UMR106 osteosarcoma cells [PDF]
, 2007 Bisphosphonates are nonhydrolysable pyrophosphate analogues that prevent bone loss in several types of cancer. However, the mechanisms of anticancer action of bisphosphonates are not completely known.
Bruzzone, L. +2 more
core +2 more sources
Pharmacokinetics of alendronate in a combined Alendronate/Vitamin D3 tablet in healthy volunteers using plasma and urine data [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2013 Alendronate is indicated for treatment of a variety of bone metabolism disorders. In spite of quite low plasma concentrationsfollowing oral administration, pharmacokinetic study of alendronate based on plasma concentrations had normally been reported for
Chalitpon Na nakorn +3 more
doaj
Journal of Cachexia, Sarcopenia and Muscle, 2018 Background A global consensus on the loss of skeletal muscle mass and function in humans refers as sarcopenia and cachexia including diabetes, obesity, renal failure, and osteoporosis. Despite a current improvement of sarcopenia or cachexia with exercise
Hsien‐Chun Chiu +5 more
doaj +1 more source
Osteogenic effects of simvastatin-loaded mesoporous titania thin films [PDF]
, 2018 The use of statins in the field of bone regeneration is under current investigation due to the existing demand for non-toxic anabolic agents capable of enhancing bone formation in cases of substantial loss. Simvastatin, a coenzyme currently prescribed in
Angelome, Paula Cecilia +7 more
core +1 more source
Effect of regression to the mean on decision making in health care [PDF]
, 2003 Knowledge of regression to the mean can help with everything from interpreting test results to improving your career prospects.
Morton, V, Torgerson, D J
core +2 more sources
British Journal of Clinical Pharmacology, EarlyView.This original research used medication administration data to explore adherence to treatment guidelines for the most common osteoporosis medications in long‐term residential aged care (RAC) in Australia. The paper highlights gaps in adherence to treatment guidelines that must be addressed to improve outcomes of older adults living in RAC.
Marea O'Donnell +7 more
wiley +1 more source
Bisphosphonate inhibits the expression of cyclin A2 at the transcriptional level in normal human oral keratinocytes. [PDF]
, 2017 Nitrogen-containing bisphosphonates (N-BPs) are the most widely used anti-resorptive agents in the treatment of bone-related diseases. N-BPs inhibit bone resorption by specifically targeting osteoclasts, bone-resorbing cells.
Kang, Mo K +5 more
core +1 more source
JRSM, 2002 Alendronate and other bisphosphonates are effective in the prevention and treatment of osteoporosis by inhibiting bone resorption. In normal circumstances a small initial fall in serum calcium has no clinical consequences because it is corrected by an increase in parathyroid hormone (PTH) secretion1.
Richard J, Maclsaac +2 more
openaire +3 more sources
Clinical Advances in Periodontics, EarlyView.Abstract Background Medication‐related osteonecrosis of the jaw (MRONJ) is a challenging complication associated with antiresorptive medications. Its exact pathophysiology remains unclear, but dental extractions and infections are known triggers, complicating prevention, and treatment.
Pedro Franco Ferreira +3 more
wiley +1 more source
Effect of Vitamin K and Alendronate Combination Treatment on Bone Mineral Density of Postmenopausal Osteoporosis Patients: A Pilot Study [PDF]
Patient Safety and Quality Improvement Journal, 2016 Introduction: Osteoporosis is a common problem in postmenopausal women. Numerous studies investigated the effects of vitamin K on bone health, which yielded conflicting results.
Mohammad Hassan Jokar +3 more
doaj