Results 31 to 40 of about 13,763 (191)

Hypoparathyroidism unmasked by alendronate [PDF]

Postgraduate Medical Journal, 2000
Abstract The case of an elderly woman is reported in whom alendronate, given for osteoporosis, led to severe hypocalcaemia a few days after starting the drug treatment. This was caused by the unmasking of previously unrecognised hypoparathyroidism.
A S, Kashyap, S, Kashyap
openaire   +2 more sources

Romosozumab Followed by Antiresorptive Treatment Increases the Probability of Achieving Bone Mineral Density Treatment Goals

JBMR Plus, 2021
Increases in bone mineral density (BMD) with osteoporosis treatment are associated with reduced fracture risk. Increasing BMD is therefore a goal of osteoporosis therapy.
Felicia Cosman, Cesar Libanati, Cynthia Deignan, Zhigang Yu, Zhenxun Wang, Serge Ferrari, Jens‐Erik Beck Jensen, Pilar Peris, Francesco Bertoldo, Eric Lespessailles, Eric Hesse, Steven R Cummings   +11 more
doaj   +1 more source

Alendronate nanoparticles promote fracture healing by inhibiting LRP4 to activate the Wnt/β-catenin pathway

European Cells & Materials
Background: Fracture is a common skeletal disorder, and fracture healing is a complex biological process. The Wingless-Int-Integrated/beta-catenin (Wnt/β-catenin) signaling pathway plays an important role in bone formation and fracture healing.
ZW Sun, QL Zhu, JP Gong, YH Sui, XY Liu
doaj   +1 more source

Common osteoporosis drug associated with increased rates of depression and anxiety

Scientific Reports, 2021
Osteoporosis affects over 10 million Americans over 50. Bisphosphonate therapy, mainly alendronate, is amongst the most prescribed treatments for the disease.
Dro Keshishi, Tigran Makunts, Ruben Abagyan   +2 more
doaj   +1 more source

A fast and simple spectrofluorometric method for the determination of alendronate sodium in pharmaceuticals [PDF]

BioImpacts, 2014
Introduction: Alendronate sodium enhances bone formation and increases osteoblast proliferation and maturation and leads to the inhibition of osteoblast apoptosis.
Jafar Ezzati Nazhad Dolatabadi, Hamed Hamishehkar, Miguel de la Guardia, Hadi Valizadeh   +3 more
doaj   +1 more source

Pharmacokinetics of alendronate in a combined Alendronate/Vitamin D3 tablet in healthy volunteers using plasma and urine data [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2013
Alendronate is indicated for treatment of a variety of bone metabolism disorders. In spite of quite low plasma concentrationsfollowing oral administration, pharmacokinetic study of alendronate based on plasma concentrations had normally been reported for
Chalitpon Na nakorn, Narubodee Phadungsombut, Thitima Chuchome, Kamonthip Wiwattanawongsa   +3 more
doaj  

Preventing muscle wasting by osteoporosis drug alendronate in vitro and in myopathy models via sirtuin‐3 down‐regulation

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background A global consensus on the loss of skeletal muscle mass and function in humans refers as sarcopenia and cachexia including diabetes, obesity, renal failure, and osteoporosis. Despite a current improvement of sarcopenia or cachexia with exercise
Hsien‐Chun Chiu, Chen‐Yuan Chiu, Rong‐Sen Yang, Ding‐Cheng Chan, Shing‐Hwa Liu, Chih‐Kang Chiang   +5 more
doaj   +1 more source

Effect of alendronate and platelet-rich plasma in tendon-bones integration in sheep anterior cruciate ligament surgery [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Anterior cruciate ligament (ACL) reconstruction often faces challenges due to poor integration of the tendon with bone. Aims: To evaluate the potential benefits of alendronate and platelet-rich plasma (PRP) in enhancing tendon-to-bone ...
Tangkas Sibarani, Bambang Purwanto, Ambar Mudigdo, Brian Wasita   +3 more
doaj   +1 more source

Esophageal ulcer and alendronate [PDF]

Sao Paulo Medical Journal, 1998
OBJECTIVE: To describe a case of esophageal ulcer associated with the use of alendronate. CASE REPORT: This is the fifth case ever described in the literature according to our bibliographic review. In our patient, the association between the drug and the esophageal lesions was masked by the presence of a hiatal hernia, potentially a cause of the ...
Angelo Paulo Ferrari Junior, Sérgio Hernani Stuhr Domingues   +1 more
openaire   +3 more sources

Modified Titanium Dental Implants: The Current Progress of Soft‐Tissue Integration Methods

Advanced NanoBiomed Research, EarlyView.
Dental implants are an established solution for tooth loss, yet achieving soft tissue integration (STI) around the transmucosal region remains a challenge. The natural tooth–gingiva interface is poorly replicated on titanium implants. This review explores surface modification strategies, ranging from surface chemistry and topography to biological ...
Daniel De Maria, Amy Gelmi, Peter C. Sherrell, Stefan Di Medio, Nhiem Tran, Kate Fox   +5 more
wiley   +1 more source