JBMR Plus, 2021 Increases in bone mineral density (BMD) with osteoporosis treatment are associated with reduced fracture risk. Increasing BMD is therefore a goal of osteoporosis therapy.
Felicia Cosman +11 more
doaj +1 more source
Positioning novel biologicals in CKD-mineral and bone disorders [PDF]
, 2017 Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian +5 more
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Common osteoporosis drug associated with increased rates of depression and anxiety
Scientific Reports, 2021 Osteoporosis affects over 10 million Americans over 50. Bisphosphonate therapy, mainly alendronate, is amongst the most prescribed treatments for the disease.
Dro Keshishi +2 more
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Coping with complexity: working beyond the guidelines for patients with multimorbidities [PDF]
, 2015 Primary care physicians believe they are delivering evidence-based care, understanding that adherence to evidence-based clinical guidelines results in tangible benefits in the populations for which they were developed.
Treadwell, Julian
core +3 more sources
European Cells & MaterialsBackground: Fracture is a common skeletal disorder, and fracture healing is a complex biological process. The Wingless-Int-Integrated/beta-catenin (Wnt/β-catenin) signaling pathway plays an important role in bone formation and fracture healing.
ZW Sun, QL Zhu, JP Gong, YH Sui, XY Liu
doaj +1 more source
A fast and simple spectrofluorometric method for the determination of alendronate sodium in pharmaceuticals [PDF]
BioImpacts, 2014 Introduction: Alendronate sodium enhances bone formation and increases osteoblast proliferation and maturation and leads to the inhibition of osteoblast apoptosis.
Jafar Ezzati Nazhad Dolatabadi +3 more
doaj +1 more source
Biomechanical Computed Tomography analysis (BCT) for clinical assessment of osteoporosis. [PDF]
, 2020 The surgeon general of the USA defines osteoporosis as "a skeletal disorder characterized by compromised bone strength, predisposing to an increased risk of fracture." Measuring bone strength, Biomechanical Computed Tomography analysis (BCT), namely ...
Bouxsein, ML +6 more
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Biological evaluations of novel 2,3,3-Trisphosphonate in osteoclastic and osteoblastic activities [PDF]
, 2017 Bisphosphonates (BPs) are the first line treatment for many bone diseases including hypercalcimia associated with bone malignancies. In this paper, we introduce a new analogue of bisphosphonate called the 2,3,3-Trisphosphonate (2,3,3-TriPP) that was ...
Boccaccini, Aldo R. +4 more
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6'-Methoxy Raloxifene-analog enhances mouse bone properties with reduced estrogen receptor binding [PDF]
, 2020 Raloxifene (RAL) is an FDA-approved drug used to treat osteoporosis in postmenopausal women. RAL suppresses bone loss primarily through its role as a selective estrogen receptor modulator (SERM).
Allen, Matthew R. +9 more
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Effect of alendronate and platelet-rich plasma in tendon-bones integration in sheep anterior cruciate ligament surgery [PDF]
Journal of Pharmacy & Pharmacognosy ResearchContext: Anterior cruciate ligament (ACL) reconstruction often faces challenges due to poor integration of the tendon with bone. Aims: To evaluate the potential benefits of alendronate and platelet-rich plasma (PRP) in enhancing tendon-to-bone ...
Tangkas Sibarani +3 more
doaj +1 more source