A Randomized, Double-Blind, Controlled Phase III Clinical Trial to Evaluate the Immunogenicity and Safety of a Lyophilized Human Rabies Vaccine (Vero Cells) in Healthy Participants Aged 10–60 Years Following Essen and Zagreb Vaccination Procedures [PDF]
Objective: In this paper, we aim to show that the immunogenicity of the lyophilized human rabies vaccine (Vero cells) (investigational vaccine) developed by Dalian Aleph Biomedical Co., Ltd. in healthy participants aged 10–60 years old is non-inferior to
Xiaohong Wu +17 more
doaj +2 more sources
A simulated, randomized study on the safety and immunogenicity of three consecutive commercial-scale batches of the CTN-1V strain human rabies vaccine to verify the inter-batch consistency [PDF]
In this study, we sought to evaluate the inter-batch consistency and safety of the CTN-1 V human rabies vaccine (Vero cells). A total of 594 healthy participants aged 10–60 years were enrolled from Mianzhu, Sichuan Province, and randomized into three ...
Lei Zhou +13 more
doaj +2 more sources
Immunogenicity and safety of the quadrivalent inactivated split-virion influenza vaccine in populations aged ≥ 3 years: A phase 3, randomized, double-blind, non-inferiority clinical trial [PDF]
This study aimed to evaluate the immunogenicity non-inferiority and safety of the quadrivalent inactivated split-virion influenza vaccine in participants ≥ 3 years old. A total of 3,328 participants were enrolled.
Jianmin Chen +15 more
doaj +2 more sources
Guiding AlphaFold predictions with experimental knowledge to inform dynamics and interactions with VAIRO. [PDF]
Abstract Structural predictions have reached unprecedented accuracy. They leverage sequence‐specific data to capture all potential interactions a sequence has evolved to fulfill. AlphaFold derives information from three sources: learned parameters capturing intrinsic amino acid secondary structure and environment propensity; models of related proteins ...
Triviño J +14 more
europepmc +2 more sources
On fractional Caputo operator for the generalized glucose supply model via incomplete Aleph function
In this paper, we have attempted a fresh method to demonstrate how special functions and fractional calculus are used in real-world problems. Here, we have examined the glucose supply in human blood using the incomplete Aleph function (IAF) and the ...
, , Ravi Shanker Dubey
exaly +3 more sources
Construction of Ordinal Numbers and Arithmetic of Ordinal Numbers
The purpose of this paper is to introduce the idea of how to construct transfinite numbers and study transfinite arithmetic. The research method used is a literature review, which involves collecting various sources such as scientific papers and books ...
Denik Agustito +3 more
doaj +1 more source
Science and art are often disconnected but, if combined, can help stimulate learning and novelty and guide societal change. How then to bridge the divide between scientists and artists in a way that extends beyond superficial, short-term interactions? We
Henrik Österblom +2 more
doaj +1 more source
Normality in Uncountable Groups [PDF]
The main purpose of this paper is to describe the structure of uncountable groups of cardinality $\aleph$ in which all subgroups of cardinality $\aleph$ are normal.
Maria De Falco +3 more
doaj +1 more source
Using Mellin-Barnes contour integrals, we aim at suggesting a q-analogue (q-extension) of the several variable Aleph-function. Then we present Riemann Liouville fractional q-integral and q-differential formulae for the q-extended several variable Aleph ...
Dinesh Kumar +3 more
doaj +1 more source
On Transformation Involving Basic Analogue to the Aleph-Function of Two Variables
In our work, we derived the fractional order q-integrals and q-derivatives concerning a basic analogue to the Aleph-function of two variables (AFTV). We discussed a related application and the q-extension of the corresponding Leibniz rule.
Dinesh Kumar +3 more
doaj +1 more source

