Results 31 to 40 of about 844,715 (299)

Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double-blind, pilot study. [PDF]

, 2015
The primary treatment outcomes of a phase 2, randomized, double-blind, pilot study evaluating safety, physiological, and pharmacological effects of elosulfase alfa in patients with Morquio A syndrome are herewith presented.
Berger, Kenneth I, Burton, Barbara K, Genter, Fred, Harmatz, Paul, Jones, Simon A, Lau, Heather, Lewis, Gregory D, Mitchell, John J, Muschol, Nicole, Pastores, Gregory M, Shaywitz, Adam J, Sparkes, Rebecca, Sutton, V Reid, Tarnopolsky, Mark, Treadwell, Marsha   +14 more
core   +1 more source

Perfil eletroforético das proteínas séricas de serpentes Crotalus durissus terrificus (cascavel) criadas em cativeiro Serum protein electrophoresis profile of the rattlesnake Crotalus durissus terrificus kept in captivity

Pesquisa Veterinária Brasileira, 2009
As serpentes peçonhentas dos gêneros Bothrops e Crotalus têm sido mantidas em cativeiro visando à extração de venenos para a produção de imunobiológicos.
Joandes Henrique Fonteque, Aguemi Kohayagawa, Regina Kiomi Takahira, Ednelson Henrique Bianchi, André Luís Cherubini, Adriana Piccinin, Edson Marcelo Bruder, Paulo Roberto Rodrigues Ramos   +7 more
doaj   +1 more source

La crux gemmata de la basílica de San Filóxeno de Oxirrinco (El-Bahnasa, Egipto)

Imafronte
El artículo se centra en el estudio de una crux gemmata descubierta en la basílica de San Filóxeno en Oxirrinco (Egipto), explorando su contexto histórico, significado simbólico e iconografía.
José Javier Martínez García, Adriana Recasens Escardó   +1 more
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Fatores críticos de sucesso no processo de implementação do balanced scorecard: um estudo de caso nas instituições federais de ensino superior

Revista de Ciências da Administração : RCA, 2016
Este artigo tem como objetivo apreender as práticas de gestão adotadas a partir do planejamento estratégico, estabelecendo as prioridades de atuação em cada área.
Marcos Ribeiro Cunha, Lúcia Kratz
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Perfil sociodemográfico da leishmaniose tegumentar americana em Almenara – Minas Gerais

Pubvet, 2020
Objetivo: caracterizar o perfil sociodemográfico da LTA no município de Almenara – MG entre os anos de 2016-2018, considerando-se dados da notificação oficial fornecidos pelo setor de vigilância do município.
Djully Borges da Silva Araújo, Ednardo de Souza Nascimento, Viviane Amaral Toledo Coelho, Carla Giselly de Souza, Mônica Cecília Santana Pereira   +4 more
doaj   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

Active Microrheology of Networks Composed of Semiflexible Polymers. II. Theory and comparison with simulations

, 2005
Building on the results of our computer simulation (ArXiv cond-mat/0503573)we develop a theoretical description of the motion of a bead, embedded in a network of semiflexible polymers, and responding to an applied force.
A. Boulbitch, A. J. Levine, B. Alberts, D. A. Pink, F. G. Schmidt, F. Gittes, H. C. Brinkman, L. D. Landau, L. D. Landau, N. Ter-Oganessian, N. W. Tschoegl, W. Helfrich   +11 more
core   +1 more source

Purification and Characterization of Recombinant Darbepoetin Alfa from Leishmania tarentolae [PDF]

, 2016
Darbepoetin alfa is a biopharmaceutical glycoprotein that stimulates erythropoiesis and is used to treat anemia, which associated with renal failure and cancer chemotherapy.
Ansari, J., Evazalipour, M., Kianmehr, A., Mahrooz, A., Oladnabi, M., Omidinia, E., Safdari, Y., Shahbazmohammadi, H., Veisi, K.   +8 more
core   +1 more source