Results 141 to 150 of about 21,477 (310)

Patient‐Centric First‐in‐Human Dose Selection: An Ex Vivo Minimal Anticipated Biological Effect Level Approach for T‐Cell Engagers in Multiple Myeloma

Clinical Pharmacology &Therapeutics, EarlyView.
The minimal anticipated biological effect level (MABEL) approach to first‐in‐human (FIH) dose calculation can lead to long dose‐escalation periods before observing clinical activity. We used a novel ex vivo MABEL approach to calculate the FIH starting dose for forimtamig, a T‐cell bispecific antibody under investigation for the treatment of relapsed ...
Thomas E. Kraft, Estelle Marrer‐Berger, Sara Belli, Helene Haegel, Anneliese Schneider, Anna Maria Giusti, Michael Bscheider, Wolfgang Jacob, Martin Weisser, Laura Blanco, Nicolas Frances, Eva Rossmann, Guido Steiner, Aintzane Zabaleta Azpiroz, Bruno Paiva, Ludovic Martinet, Tanja Fauti   +16 more
wiley   +1 more source

Same critical aspects regardless of age – indicating lack of experiences of algebraic expressions

, 2019
The issue for this paper is to discuss what can explain that students in different grades seem to experience a phenomenon in more or less the same way and thus, need to discern the same critical aspects in teaching.
Gerholm, Werner,, Nordin, Anna-Karin,, Fermsjö, Roger,, Nyman, Martin,, Eriksson, Inger,, Fred, Jenny,, Wettergren, Sanna,   +6 more
core  

Sustainability‐Oriented Collaborations in Green Energy Markets Formation: A Configurational Analysis of Alliance Management Capabilities and Relational View

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Sustainability‐oriented collaborations are inter‐organisational arrangements where the competencies of multiple companies are pooled together to tackle environmental challenges. These collaborations differ from traditional strategic alliances in that they tackle complex goals amidst greater uncertainties that extend beyond economic performance,
Vittorio Maria Garibbo, Eleonora Annunziata, Francesco Rizzi, Marco Frey   +3 more
wiley   +1 more source

Algebraic basis for Physics

This manuscript derives General relativity, Quantum Field dynamics and Quantum Gravity with BCH operators on G2 Lie Algebra independent of Octonionic mathematical ...
openaire   +3 more sources

Photometric Diagnostic of the Sheath Dynamics and Electron Density Trends in Single and Dual Frequency CCRF Argon Plasmas

Contributions to Plasma Physics, EarlyView.
ABSTRACT A methodological study is presented on a noninvasive photometric diagnostic for determining trends in electron density and sheath dynamics in single (1f) and a dual (2f) radio frequency capacitively coupled (CCRF) argon plasmas. The 1f discharges are operated at 13.56 and 27.12 MHz, respectively, while the 2f discharge is driven by both ...
Daniel Zuhayra, Jessica Niemann, Viktor Schneider, Holger Kersten   +3 more
wiley   +1 more source

Better than Trees: Applying Semilattices to Balance the Accuracy and Complexity of Machine Learning Models

Machine Learning and Knowledge Extraction
Balancing the accuracy and the complexity of models is a well established and ongoing challenge. Models can be misleading if they are not accurate, but models may be incomprehensible if their accuracy depends upon their being complex.
Stephen Fox, Antonio Ricciardo
doaj   +1 more source

Representations of fundamental groups of algebraic varieties

, 1999
Using harmonic maps, non-linear PDE and techniques from algebraic geometry this book enables the reader to study the relation between fundamental groups and algebraic geometry invariants of algebraic varieties. The reader should have a basic knowledge of
Zuo, Kang
core   +1 more source

Kinetic Contribution to the Arbitrary Order Odd Frequency Moments of the Dynamic Structure Factor

Contributions to Plasma Physics, EarlyView.
ABSTRACT An exact expression is derived for the kinetic contribution to the odd (arbitrary order) frequency moments of the dynamic structure factor via a finite summation that features averages of even (all lower orders) powers of the momentum over the exact momentum distribution.
Panagiotis Tolias, Tobias Dornheim, Jan Vorberger   +2 more
wiley   +1 more source

Boson–Fermion Algebraic Mapping in Second Quantization

Entropy
We present an algebraic method to derive the structure at the basis of the mapping of bosonic algebras of creation and annihilation operators into fermionic algebras, and vice versa, introducing a suitable identification between bosonic and fermionic ...
Fabio Lingua, Diego Molina Peñafiel, Lucrezia Ravera, Sebastián Salgado   +3 more
doaj   +1 more source

Review and prospects of shear test of bolted rock joints

Deep Underground Science and Engineering, EarlyView.
The laboratory shear test equipment, test method, and numerical simulation of bolted rock joints were summarized. The shortcomings and limitations of the current research were analyzed, and the research prospects were proposed. Abstract Rock bolting is a critical approach in geotechnical engineering for supporting weak rocks.
Shulin Ren, Fan Yang, Manchao He, Yong Yuan, Zhigang Tao   +4 more
wiley   +1 more source