Results 91 to 100 of about 7,539,705 (335)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
CMT: An Efficient Algorithm for Scalable Packet Classification [PDF]
, 2021 Shuhui Chen +4 more
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
IEEE AccessLarge-scale image and text representation learning is critical in determining the performance of multimodal tasks involving images and text, such as visual question answering and image captioning.
Yang Qin, Shuxue Ding, Huiming Xie
doaj +1 more source
An Improved QSPR Modeling of Hydrocarbon Dipole Moments
The Scientific World Journal, 2004 Dipole moments of hydrocarbons are not an easy property to model with conventional 2D descriptors. A comparison of the performance of the most commonly used sets of topological descriptors is presented, each set containing descriptors derived from the ...
Igor V. Nesterov +3 more
doaj +1 more source
Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging [PDF]
, 2020 Mariana Boroni +6 more
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Multiple Testing with the Structure-Adaptive Benjamini–Hochberg Algorithm [PDF]
, 2018 Ang Li, Rina Foygel Barber
openalex +1 more source
Improving the Performance of Multiobjective Genetic Algorithms: An Elitism-Based Approach [PDF]
, 2020 Giorgio Guariso, Matteo Sangiorgio
openalex +1 more source