Results 51 to 60 of about 7,454,542 (339)

Accelerated Backpressure Algorithm

, 2013
We develop an Accelerated Back Pressure (ABP) algorithm using Accelerated Dual Descent (ADD), a distributed approximate Newton-like algorithm that only uses local information.
Jadbabaie, Ali, Ribeiro, Alejandro, Zargham, Michael   +2 more
core   +1 more source

A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits [PDF]

, 2021
Christopher N. Foley, James R Staley, Philip G. Breen, Benjamin B. Sun, Paul Kirk, Stephen Burgess, Joanna M. M. Howson   +6 more
openalex   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

A hybrid clustering algorithm for data mining

, 2012
Data clustering is a process of arranging similar data into groups. A clustering algorithm partitions a data set into several groups such that the similarity within a group is better than among groups. In this paper a hybrid clustering algorithm based on
Jain, Ravindra
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Dense symmetric temporal alignment learning for human pose estimation [PDF]

PeerJ Computer Science
Human pose estimation aims to locate the human joint positions from images or videos. This problem has drawn increasing attention and wide applications in autonomous driving, motion analysis, and intelligence robotics.
Guang Xv, Xingchen Wu
doaj   +2 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Foggy Drone Teacher: Domain Adaptive Drone Detection Under Foggy Conditions

Drones
With the growing use of drones, efficient detection algorithms are crucial, especially under adverse weather conditions. Most existing drone detection algorithms perform well only in clear weather, resulting in significant performance drops in foggy ...
Guida Zheng, Benying Tan, Jingxin Wu, Xiao Qin, Yujie Li, Shuxue Ding   +5 more
doaj   +1 more source

Impact of surgical complications on hospital costs and revenues: retrospective database study of Medicare claims

Journal of Comparative Effectiveness Research, 2023
Aim: To compare the length of stay, hospital costs and hospital revenues for Medicare patients with and without a subset of potentially preventable postoperative complications after major noncardiac surgery.
Samer Haidar, Reynaldo Vazquez, Goran Medic   +2 more
doaj   +1 more source