Results 51 to 60 of about 2,784,783 (318)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Foggy Drone Teacher: Domain Adaptive Drone Detection Under Foggy Conditions

open access: yesDrones
With the growing use of drones, efficient detection algorithms are crucial, especially under adverse weather conditions. Most existing drone detection algorithms perform well only in clear weather, resulting in significant performance drops in foggy ...
Guida Zheng   +5 more
doaj   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

Target Association of Heterogeneous Sensors Based on Nearest-neighbor and Topology

open access: yesLeida xuebao, 2012
A new data association algorithm is proposed in this paper for heterogeneous sensors information fusion system, which consists of Radar and high-dynamic-range IR, based on joint usage of the nearest-neighbor (NN) and the topology similarity. The proposed
Yuan Ding-bo   +3 more
doaj   +1 more source

Algorithms, Algorithms, Algorithms [PDF]

open access: yesComputer, 2020
James Bret Michael, Jeffrey Voas
openaire   +2 more sources

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Sequential Recommendation Based on Multi-space Attribute Information Fusion [PDF]

open access: yesJisuanji kexue
The goal of sequential recommendation is to model users' dynamic interests from their historical behaviors,and hence to make recommendations related to the users' interests.Recently,attribute information has been demonstrated to improve the performance ...
WANG Zihong, SHAO Yingxia, HE Jiyuan, LIU Jinbao
doaj   +1 more source

On quantum algorithms

open access: yesComplexity, 1998
15 pages, 8 ...
Cleve, R   +4 more
openaire   +6 more sources

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

open access: yesMolecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton   +17 more
wiley   +1 more source

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