Results 51 to 60 of about 386,495 (263)

Computing the multifractal spectrum from time series: An algorithmic approach

open access: yes, 2009
We show that the existing methods for computing the f(\alpha) spectrum from a time series can be improved by using a new algorithmic scheme. The scheme relies on the basic idea that the smooth convex profile of a typical f(\alpha) spectrum can be fitted ...
Belloni T.   +8 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Algorithmic bias and the Value Sensitive Design approach

open access: yesInternet Policy Review, 2020
Recently, amid growing awareness that computer algorithms are not neutral tools but can cause harm by reproducing and amplifying bias, attempts to detect and prevent such biases have intensified.
Judith Simon   +2 more
doaj   +1 more source

An Algorithmic Approach to Information and Meaning [PDF]

open access: yes, 2011
I will survey some matters of relevance to a philosophical discussion of information, taking into account developments in algorithmic information theory (AIT).
Zenil, Hector
core   +4 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Lagrange Multivariate Polynomial Interpolation: A Random Algorithmic Approach

open access: yesJournal of Applied Mathematics, 2022
The problems of polynomial interpolation with several variables present more difficulties than those of one-dimensional interpolation. The first problem is to study the regularity of the interpolation schemes.
A. Essanhaji, M. Errachid
doaj   +1 more source

Unleashing Creative Synergies: A Mixed-Method Case Study in Music Education Classrooms

open access: yesApplied Sciences, 2023
Algorithmic music composition has been gaining prominence and recognition as an innovative approach to music education, providing students with opportunities to explore creativity, computational thinking, and musical knowledge.
Mário Anibal Cardoso   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

An algorithmic approach to chronic dyspnea [PDF]

open access: yesRespiratory Medicine, 2011
The objective of the study was to prospectively evaluate an algorithmic approach to the cause(s) of chronic dyspnea. MATERIALS/PATIENTS/METHODS: Prospective observational study. The study group consisted of 123 patients with a chief complaint of dyspnea of unknown cause present for >8 weeks.
Pratter, Melvin R.   +4 more
openaire   +2 more sources

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