Results 51 to 60 of about 1,725,284 (283)
Entropy, 2019 The principle of maximum entropy (Maxent) is often used to obtain prior probability distributions as a method to obtain a Gibbs measure under some restriction giving the probability that a system will be in a certain state compared to the rest of the ...
Hector Zenil +2 more
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Toward a Simulation Model Complexity Measure
Information, 2023 Is it possible to develop a meaningful measure for the complexity of a simulation model? Algorithmic information theory provides concepts that have been applied in other areas of research for the practical measurement of object complexity.
J. Scott Thompson +4 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Computational complexity, algorithmic scope, and evolution
Journal of Physics: ComplexityBiological systems are widely regarded as performing computations. It is much less clear, however, what exactly is computed and how biological computation fits within the framework of standard computer science.
Leonhard Sidl +7 more
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Engineering Proceedings, 2023 This paper is devoted to the evaluation of the hardware resources of computer systems for solving a computationally expensive problem such as the calculation of the probability distributions of statistics by the second multiplicity method based on Δ ...
Andrey Melnikov +3 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Pattern-oriented algorithmic complexity: towards compression-based information retrieval [PDF]
, 2010 The assimilation of informational content to computational complexity is more than 50 years old, but a way of exploiting practically this idea came only recently with the definition of compression-based similarity measures, which estimate the amount of ...
Cerra, Daniele
core
STUDY OF SOLUTION REPRESENTATION LANGUAGE INFLUENCE ON EFFICIENCY OF INTEGER SEQUENCES PREDICTION [PDF]
Научно-технический вестник информационных технологий, механики и оптики, 2015 Methods based on genetic programming for the problem solution of integer sequences extrapolation are the subjects for study in the paper. In order to check the hypothesis about the influence of language expression of program representation on the ...
A. S. Potapov +2 more
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Quantifying evoked responses through information-theoretical measures
Frontiers in Neuroinformatics, 2023 Information theory is a viable candidate to advance our understanding of how the brain processes information generated in the internal or external environment. With its universal applicability, information theory enables the analysis of complex data sets,
Julian Fuhrer +13 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source