Results 21 to 30 of about 8,117 (256)
Algorithmic Bias: Identification of Algorithmic Bias, Its Interference in Corporate Governance, and Board‑Level Remedies – In Indian Boards [PDF]
ITM Web of ConferencesAlgorithmic decision-making (ADM) systems increasingly shape Corporate Governance processes, from hiring and performance evaluation to Financial Risk Management.
Sundararajan Narendran, V Ramesh
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Towards Just AI: Challenges and Solution Framework for Algorithmic Discrimination in Judicial System
International Journal of Digital Law and GovernanceWith the rapid development of technologies like big data, artificial intelligence (herein after AI), and blockchain, society is ushering into a new era of digital civilization.
Dou Landuo, Dou Xiaodong
doaj +1 more source
Defence and criticism of algorithmic governance
Revista CIDOB d'Afers InternacionalsThe problem of the relationship between algorithmic governance and democracy represents at once continuity and a break with traditional forms of bureaucratic administration.
Daniel Innerarity
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
University rankings and governance by metrics and algorithms [PDF]
, 2021 This paper looks closely at how data analytic providers leverage rankings as a part of their strategies to further extract rent and assets from the university beyond their traditional roles as publishers and citation data providers. Multinational publishers such as Elsevier, with over 2,500 journals in its portfolio, has transitioned to become a data ...
Chen, George, Chan, Leslie
openaire +2 more sources
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source