Results 51 to 60 of about 21,469 (254)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Secure Blockchain Integration Approach for Knowledge Discovery in Industrial Internet of Things

IEEE Open Journal of the Communications Society
The field of Industrial Internet of Things (IIoT) is now being duly recognized as a revolutionary area in industrial automation. With the budding interest of knowledge discovery that helps the businesses in applying technology on a large scale ...
Rohan Tripathi, Ritam Rao, Vivekananda Bhat K., Abhishek Kumar Pandey, Ashok Kumar Das   +4 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Provably Secure and Efficient Authentication Protocol for Roaming Service in Global Mobility Networks

IEEE Access, 2017
In global mobility networks, a mobile user can access roaming services using a mobile device at anytime and anywhere. However, mobile users can be vulnerable to various attacks by adversaries, because the roaming services are provided through public ...
Kisung Park, Youngho Park, Yohan Park, Alavalapati Goutham Reddy, Ashok Kumar Das   +4 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

A Secure Anonymous Authentication Protocol for Mobile Services on Elliptic Curve Cryptography

IEEE Access, 2016
Mobile user authentication is an essential topic to consider in the current communications technology due to greater deployment of handheld devices and advanced technologies. Memon et al.
Alavalapati Goutham Reddy, Ashok Kumar Das, Eun-Jun Yoon, Kee-Young Yoo   +3 more
doaj   +1 more source

A Tutorial and Future Research for Building a Blockchain-Based Secure Communication Scheme for Internet of Intelligent Things

IEEE Access, 2020
The Internet of Intelligent Things (IoIT) communication environment can be utilized in various types of applications (for example, intelligent battlefields, smart healthcare systems, the industrial internet, home automation, and many more ...
Mohammad Wazid, Ashok Kumar Das, Sachin Shetty, Minho Jo   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Algorithmic Information Theory: Open Problems

J. Univers. Comput. Sci., 1996
JUCS - Journal of Universal Computer Science Volume Nr.
openaire   +3 more sources

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source